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Items: 1 to 20 of 69

1.

Filaggrin mutations increase the risk for persistent dry skin and eczema independent of sensitization.

Böhme M, Söderhäll C, Kull I, Bergström A, van Hage M, Wahlgren CF.

J Allergy Clin Immunol. 2012 Apr;129(4):1153-5. doi: 10.1016/j.jaci.2011.11.032. Epub 2012 Feb 22. No abstract available.

PMID:
22360978
2.

Predictive value of food sensitization and filaggrin mutations in children with eczema.

Filipiak-Pittroff B, Schnopp C, Berdel D, Naumann A, Sedlmeier S, Onken A, Rodriguez E, Fölster-Holst R, Baurecht H, Ollert M, Ring J, Cramer C, von Berg A, Bauer CP, Herbarth O, Lehmann I, Schaaf B, Koletzko S, Wichmann HE, Heinrich J, Weidinger S; GINIplus and LISAplus study groups.

J Allergy Clin Immunol. 2011 Dec;128(6):1235-1241.e5. doi: 10.1016/j.jaci.2011.09.014. Epub 2011 Oct 26.

PMID:
22030464
3.

Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march.

Marenholz I, Nickel R, Rüschendorf F, Schulz F, Esparza-Gordillo J, Kerscher T, Grüber C, Lau S, Worm M, Keil T, Kurek M, Zaluga E, Wahn U, Lee YA.

J Allergy Clin Immunol. 2006 Oct;118(4):866-71. Epub 2006 Sep 1.

PMID:
17030239
4.

Risk analysis of early childhood eczema.

Bisgaard H, Halkjaer LB, Hinge R, Giwercman C, Palmer C, Silveira L, Strand M.

J Allergy Clin Immunol. 2009 Jun;123(6):1355-60.e5. doi: 10.1016/j.jaci.2009.03.046.

PMID:
19501236
5.

Filaggrin gene mutations are associated with asthma and eczema in later life.

Rice NE, Patel BD, Lang IA, Kumari M, Frayling TM, Murray A, Melzer D.

J Allergy Clin Immunol. 2008 Oct;122(4):834-6. doi: 10.1016/j.jaci.2008.07.027. Epub 2008 Aug 29. No abstract available.

6.

[Filaggrin gene mutations are frequent and increase the risk of skin disease].

Meyer MW, Thyssen JP.

Ugeskr Laeger. 2011 Oct 24;173(43):2705-8. Danish.

PMID:
22027225
7.

Interplay of filaggrin loss-of-function variants, allergic sensitization, and eczema in a longitudinal study covering infancy to 18 years of age.

Ziyab AH, Karmaus W, Yousefi M, Ewart S, Schauberger E, Holloway JW, Zhang H, Arshad SH.

PLoS One. 2012;7(3):e32721. doi: 10.1371/journal.pone.0032721. Epub 2012 Mar 5.

8.

Filaggrin null mutations increase the risk and persistence of hand eczema in subjects with atopic dermatitis: results from a general population study.

Thyssen JP, Carlsen BC, Menné T, Linneberg A, Nielsen NH, Meldgaard M, Szecsi PB, Stender S, Johansen JD.

Br J Dermatol. 2010 Jul;163(1):115-20. doi: 10.1111/j.1365-2133.2010.09822.x. Epub 2010 Apr 23.

PMID:
20426775
9.

An interaction between filaggrin mutations and early food sensitization improves the prediction of childhood asthma.

Marenholz I, Kerscher T, Bauerfeind A, Esparza-Gordillo J, Nickel R, Keil T, Lau S, Rohde K, Wahn U, Lee YA.

J Allergy Clin Immunol. 2009 Apr;123(4):911-6. doi: 10.1016/j.jaci.2009.01.051.

PMID:
19348926
10.

The hands in health and disease of individuals with filaggrin loss-of-function mutations: clinical reflections on the hand eczema phenotype.

Kaae J, Menné T, Carlsen BC, Zachariae C, Thyssen JP.

Contact Dermatitis. 2012 Sep;67(3):119-24. doi: 10.1111/j.1600-0536.2012.02130.x.

PMID:
22897780
11.

The multifunctional role of filaggrin in allergic skin disease.

McAleer MA, Irvine AD.

J Allergy Clin Immunol. 2013 Feb;131(2):280-91. doi: 10.1016/j.jaci.2012.12.668. Review.

PMID:
23374260
12.

Filaggrin gene variants and atopic diseases in early childhood assessed longitudinally from birth.

Bønnelykke K, Pipper CB, Tavendale R, Palmer CN, Bisgaard H.

Pediatr Allergy Immunol. 2010 Sep;21(6):954-61. doi: 10.1111/j.1399-3038.2010.01073.x. Epub 2010 Jun 21.

PMID:
20573035
13.

Filaggrin haploinsufficiency among patients with dermatitis from a tertiary referral centre: early findings and possible phenotype.

Thyssen JP, Carlsen BC, Johansen JD, Meldgaard M, Szecsi PB, Stender S, Menné T.

Contact Dermatitis. 2010 Mar;62(3):182-3. doi: 10.1111/j.1600-0536.2009.01687.x. No abstract available.

PMID:
20565506
14.

[Mutations in the gene encoding filaggrin cause ichthyosis vulgaris].

Prasad SC, Rasmussen K, Bygum A.

Ugeskr Laeger. 2011 Feb 14;173(7):507-8. Danish.

PMID:
21320417
15.

Filaggrin loss-of-function mutation R501X and 2282del4 carrier status is associated with fissured skin on the hands: results from a cross-sectional population study.

Thyssen JP, Ross-Hansen K, Johansen JD, Zachariae C, Carlsen BC, Linneberg A, Bisgaard H, Carson CG, Nielsen NH, Meldgaard M, Szecsi PB, Stender S, Menné T.

Br J Dermatol. 2012 Jan;166(1):46-53. doi: 10.1111/j.1365-2133.2011.10530.x. Epub 2011 Nov 2.

PMID:
21777221
16.
17.

Gene-environment interaction in the onset of eczema in infancy: filaggrin loss-of-function mutations enhanced by neonatal cat exposure.

Bisgaard H, Simpson A, Palmer CN, Bønnelykke K, McLean I, Mukhopadhyay S, Pipper CB, Halkjaer LB, Lipworth B, Hankinson J, Woodcock A, Custovic A.

PLoS Med. 2008 Jun 24;5(6):e131. doi: 10.1371/journal.pmed.0050131.

18.

Loss-of-function variants of the filaggrin gene are associated with atopic eczema and associated phenotypes in Swedish families.

Ekelund E, Liedén A, Link J, Lee SP, D'Amato M, Palmer CN, Kockum I, Bradley M.

Acta Derm Venereol. 2008;88(1):15-9. doi: 10.2340/00015555-0383.

19.

Meta-analysis of filaggrin polymorphisms in eczema and asthma: robust risk factors in atopic disease.

Rodríguez E, Baurecht H, Herberich E, Wagenpfeil S, Brown SJ, Cordell HJ, Irvine AD, Weidinger S.

J Allergy Clin Immunol. 2009 Jun;123(6):1361-70.e7. doi: 10.1016/j.jaci.2009.03.036.

PMID:
19501237
20.

Eczema genetics: current state of knowledge and future goals.

Brown SJ, McLean WH.

J Invest Dermatol. 2009 Mar;129(3):543-52. doi: 10.1038/jid.2008.413. Review.

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