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Items: 1 to 20 of 210

1.

Cartilage-specific RBPjκ-dependent and -independent Notch signals regulate cartilage and bone development.

Kohn A, Dong Y, Mirando AJ, Jesse AM, Honjo T, Zuscik MJ, O'Keefe RJ, Hilton MJ.

Development. 2012 Mar;139(6):1198-212. doi: 10.1242/dev.070649.

2.

RBPjkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development.

Dong Y, Jesse AM, Kohn A, Gunnell LM, Honjo T, Zuscik MJ, O'Keefe RJ, Hilton MJ.

Development. 2010 May;137(9):1461-71. doi: 10.1242/dev.042911. Epub 2010 Mar 24.

3.

Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development.

Mead TJ, Yutzey KE.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14420-5. doi: 10.1073/pnas.0902306106. Epub 2009 Jul 9.

4.

Cartilage-specific β-catenin signaling regulates chondrocyte maturation, generation of ossification centers, and perichondrial bone formation during skeletal development.

Dao DY, Jonason JH, Zhang Y, Hsu W, Chen D, Hilton MJ, O'Keefe RJ.

J Bone Miner Res. 2012 Aug;27(8):1680-94. doi: 10.1002/jbmr.1639.

5.

Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development.

Hosaka Y, Saito T, Sugita S, Hikata T, Kobayashi H, Fukai A, Taniguchi Y, Hirata M, Akiyama H, Chung UI, Kawaguchi H.

Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1875-80. doi: 10.1073/pnas.1207458110. Epub 2013 Jan 14.

6.

Notch/Rbpjκ signaling regulates progenitor maintenance and differentiation of hypothalamic arcuate neurons.

Aujla PK, Naratadam GT, Xu L, Raetzman LT.

Development. 2013 Sep;140(17):3511-21. doi: 10.1242/dev.098681. Epub 2013 Jul 24.

8.

Notch signaling in postnatal joint chondrocytes, but not subchondral osteoblasts, is required for articular cartilage and joint maintenance.

Liu Z, Ren Y, Mirando AJ, Wang C, Zuscik MJ, O'Keefe RJ, Hilton MJ.

Osteoarthritis Cartilage. 2016 Apr;24(4):740-51. doi: 10.1016/j.joca.2015.10.015. Epub 2015 Oct 30.

9.

Notch inhibits chondrogenic differentiation of mesenchymal progenitor cells by targeting Twist1.

Tian Y, Xu Y, Fu Q, Chang M, Wang Y, Shang X, Wan C, Marymont JV, Dong Y.

Mol Cell Endocrinol. 2015 Mar 5;403:30-8. doi: 10.1016/j.mce.2015.01.015. Epub 2015 Jan 14.

10.

RBP-Jκ-dependent Notch signaling is required for murine articular cartilage and joint maintenance.

Mirando AJ, Liu Z, Moore T, Lang A, Kohn A, Osinski AM, O'Keefe RJ, Mooney RA, Zuscik MJ, Hilton MJ.

Arthritis Rheum. 2013 Oct;65(10):2623-33. doi: 10.1002/art.38076.

11.

Systemic inhibition of canonical Notch signaling results in sustained callus inflammation and alters multiple phases of fracture healing.

Dishowitz MI, Mutyaba PL, Takacs JD, Barr AM, Engiles JB, Ahn J, Hankenson KD.

PLoS One. 2013 Jul 3;8(7):e68726. doi: 10.1371/journal.pone.0068726. Print 2013.

12.

ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development.

Zhang D, Schwarz EM, Rosier RN, Zuscik MJ, Puzas JE, O'Keefe RJ.

J Bone Miner Res. 2003 Sep;18(9):1593-604.

13.

Notch gain of function inhibits chondrocyte differentiation via Rbpj-dependent suppression of Sox9.

Chen S, Tao J, Bae Y, Jiang MM, Bertin T, Chen Y, Yang T, Lee B.

J Bone Miner Res. 2013 Mar;28(3):649-59. doi: 10.1002/jbmr.1770.

14.

Canonical Notch activation in osteocytes causes osteopetrosis.

Canalis E, Bridgewater D, Schilling L, Zanotti S.

Am J Physiol Endocrinol Metab. 2016 Jan 15;310(2):E171-82. doi: 10.1152/ajpendo.00395.2015. Epub 2015 Nov 17.

15.

Canonical Notch signaling is not necessary for prosensory induction in the mouse cochlea: insights from a conditional mutant of RBPjkappa.

Basch ML, Ohyama T, Segil N, Groves AK.

J Neurosci. 2011 Jun 1;31(22):8046-58. doi: 10.1523/JNEUROSCI.6671-10.2011.

16.

Notch-Nrf2 axis: regulation of Nrf2 gene expression and cytoprotection by notch signaling.

Wakabayashi N, Skoko JJ, Chartoumpekis DV, Kimura S, Slocum SL, Noda K, Palliyaguru DL, Fujimuro M, Boley PA, Tanaka Y, Shigemura N, Biswal S, Yamamoto M, Kensler TW.

Mol Cell Biol. 2014 Feb;34(4):653-63. doi: 10.1128/MCB.01408-13. Epub 2013 Dec 2.

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RBPJkappa-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus.

Ehm O, Göritz C, Covic M, Schäffner I, Schwarz TJ, Karaca E, Kempkes B, Kremmer E, Pfrieger FW, Espinosa L, Bigas A, Giachino C, Taylor V, Frisén J, Lie DC.

J Neurosci. 2010 Oct 13;30(41):13794-807. doi: 10.1523/JNEUROSCI.1567-10.2010.

20.

The hedgehog target Vlk genetically interacts with Gli3 to regulate chondrocyte differentiation during mouse long bone development.

Probst S, Zeller R, Zuniga A.

Differentiation. 2013 Apr-Jun;85(4-5):121-30. doi: 10.1016/j.diff.2013.03.002. Epub 2013 Jun 19.

PMID:
23792766

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