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Items: 1 to 20 of 179


Target- and resistance-based mechanistic studies with TP-434, a novel fluorocycline antibiotic.

Grossman TH, Starosta AL, Fyfe C, O'Brien W, Rothstein DM, Mikolajka A, Wilson DN, Sutcliffe JA.

Antimicrob Agents Chemother. 2012 May;56(5):2559-64. doi: 10.1128/AAC.06187-11. Epub 2012 Feb 21. Erratum in: Antimicrob Agents Chemother. 2015 Sep;59(9):5870.


Propionibacterium acnes is developing gradual increase in resistance to oral tetracyclines.

Nakase K, Nakaminami H, Takenaka Y, Hayashi N, Kawashima M, Noguchi N.

J Med Microbiol. 2017 Jan;66(1):8-12. doi: 10.1099/jmm.0.000392.


Host mutations (miaA and rpsL) reduce tetracycline resistance mediated by Tet(O) and Tet(M).

Taylor DE, Trieber CA, Trescher G, Bekkering M.

Antimicrob Agents Chemother. 1998 Jan;42(1):59-64.


In vitro and in vivo antibacterial activities of a novel glycylcycline, the 9-t-butylglycylamido derivative of minocycline (GAR-936).

Petersen PJ, Jacobus NV, Weiss WJ, Sum PE, Testa RT.

Antimicrob Agents Chemother. 1999 Apr;43(4):738-44.


Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome.

Olivier NB, Altman RB, Noeske J, Basarab GS, Code E, Ferguson AD, Gao N, Huang J, Juette MF, Livchak S, Miller MD, Prince DB, Cate JH, Buurman ET, Blanchard SC.

Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16274-9. doi: 10.1073/pnas.1414401111. Epub 2014 Nov 3.


Glycylcyclines bind to the high-affinity tetracycline ribosomal binding site and evade Tet(M)- and Tet(O)-mediated ribosomal protection.

Bergeron J, Ammirati M, Danley D, James L, Norcia M, Retsema J, Strick CA, Su WG, Sutcliffe J, Wondrack L.

Antimicrob Agents Chemother. 1996 Sep;40(9):2226-8.


Occurrence of tetracycline resistance genes among Escherichia coli isolates from the phase 3 clinical trials for tigecycline.

Tuckman M, Petersen PJ, Howe AY, Orlowski M, Mullen S, Chan K, Bradford PA, Jones CH.

Antimicrob Agents Chemother. 2007 Sep;51(9):3205-11. Epub 2007 Jul 9.


Distribution and transferability of tetracycline resistance determinants in Escherichia coli isolated from meat and meat products.

Koo HJ, Woo GJ.

Int J Food Microbiol. 2011 Feb 28;145(2-3):407-13. doi: 10.1016/j.ijfoodmicro.2011.01.003. Epub 2011 Jan 15.


In vitro and in vivo antibacterial activities of the glycylcyclines, a new class of semisynthetic tetracyclines.

Testa RT, Petersen PJ, Jacobus NV, Sum PE, Lee VJ, Tally FP.

Antimicrob Agents Chemother. 1993 Nov;37(11):2270-7.


Mechanism of action of the novel aminomethylcycline antibiotic omadacycline.

Draper MP, Weir S, Macone A, Donatelli J, Trieber CA, Tanaka SK, Levy SB.

Antimicrob Agents Chemother. 2014;58(3):1279-83. doi: 10.1128/AAC.01066-13. Epub 2013 Sep 16.


Effects of efflux transporter genes on susceptibility of Escherichia coli to tigecycline (GAR-936).

Hirata T, Saito A, Nishino K, Tamura N, Yamaguchi A.

Antimicrob Agents Chemother. 2004 Jun;48(6):2179-84.


16S rRNA gene mutations associated with decreased susceptibility to tetracycline in Mycoplasma bovis.

Amram E, Mikula I, Schnee C, Ayling RD, Nicholas RA, Rosales RS, Harrus S, Lysnyansky I.

Antimicrob Agents Chemother. 2015 Feb;59(2):796-802. doi: 10.1128/AAC.03876-14. Epub 2014 Nov 17.


Prevalence of tetracycline resistance genes and identification of tet(M) in clinical isolates of Escherichia coli from sick ducks in China.

Hu GZ, Pan YS, Wu H, Hu H, Xu R, Yuan L, Liu JH, Feng JK.

J Med Microbiol. 2013 Jun;62(Pt 6):851-8. doi: 10.1099/jmm.0.051896-0. Epub 2013 Mar 8.


Characterization of tetracycline resistance genes in Escherichia coli isolated from feedlot cattle administered therapeutic or subtherapeutic levels of tetracycline.

Alexander TW, Jin X, Li Q, Cook S, McAllister TA.

Can J Microbiol. 2013 Apr;59(4):287-90. doi: 10.1139/cjm-2012-0660. Epub 2013 Feb 19.


Susceptibility of tetracyclines to Tet(a) resistance is independent of interdomain loop sequence.

Fyfe C, Sutcliffe JA, Grossman TH.

Antimicrob Agents Chemother. 2013 May;57(5):2430-1. doi: 10.1128/AAC.00393-13. Epub 2013 Mar 11. No abstract available.


Distribution of tetracycline resistance genes in genotypically related and unrelated multiresistant Acinetobacter baumannii strains from different European hospitals.

Huys G, Cnockaert M, Vaneechoutte M, Woodford N, Nemec A, Dijkshoorn L, Swings J.

Res Microbiol. 2005 Apr;156(3):348-55. Epub 2004 Dec 15.


In vitro and in vivo antibacterial activities of omadacycline, a novel aminomethylcycline.

Macone AB, Caruso BK, Leahy RG, Donatelli J, Weir S, Draper MP, Tanaka SK, Levy SB.

Antimicrob Agents Chemother. 2014;58(2):1127-35. doi: 10.1128/AAC.01242-13. Epub 2013 Dec 2.


High-level tetracycline resistance mediated by efflux pumps Tet(A) and Tet(A)-1 with two start codons.

Wang W, Guo Q, Xu X, Sheng ZK, Ye X, Wang M.

J Med Microbiol. 2014 Nov;63(Pt 11):1454-9. doi: 10.1099/jmm.0.078063-0. Epub 2014 Aug 7.


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