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Items: 1 to 20 of 390

1.

The B-cell specific transcription factor, Oct-2, promotes Epstein-Barr virus latency by inhibiting the viral immediate-early protein, BZLF1.

Robinson AR, Kwek SS, Kenney SC.

PLoS Pathog. 2012 Feb;8(2):e1002516. doi: 10.1371/journal.ppat.1002516. Epub 2012 Feb 9.

2.

The B-cell-specific transcription factor and master regulator Pax5 promotes Epstein-Barr virus latency by negatively regulating the viral immediate early protein BZLF1.

Raver RM, Panfil AR, Hagemeier SR, Kenney SC.

J Virol. 2013 Jul;87(14):8053-63. doi: 10.1128/JVI.00546-13. Epub 2013 May 15.

3.

Cellular transcription factor Oct-1 interacts with the Epstein-Barr virus BRLF1 protein to promote disruption of viral latency.

Robinson AR, Kwek SS, Hagemeier SR, Wille CK, Kenney SC.

J Virol. 2011 Sep;85(17):8940-53. doi: 10.1128/JVI.00569-11. Epub 2011 Jun 22.

4.

Hypoxia-inducible factor-1α plays roles in Epstein-Barr virus's natural life cycle and tumorigenesis by inducing lytic infection through direct binding to the immediate-early BZLF1 gene promoter.

Kraus RJ, Yu X, Cordes BA, Sathiamoorthi S, Iempridee T, Nawandar DM, Ma S, Romero-Masters JC, McChesney KG, Lin Z, Makielski KR, Lee DL, Lambert PF, Johannsen EC, Kenney SC, Mertz JE.

PLoS Pathog. 2017 Jun 15;13(6):e1006404. doi: 10.1371/journal.ppat.1006404. eCollection 2017 Jun.

5.

Cellular differentiation regulator BLIMP1 induces Epstein-Barr virus lytic reactivation in epithelial and B cells by activating transcription from both the R and Z promoters.

Reusch JA, Nawandar DM, Wright KL, Kenney SC, Mertz JE.

J Virol. 2015 Feb;89(3):1731-43. doi: 10.1128/JVI.02781-14. Epub 2014 Nov 19.

6.

BZLF1 governs CpG-methylated chromatin of Epstein-Barr Virus reversing epigenetic repression.

Woellmer A, Arteaga-Salas JM, Hammerschmidt W.

PLoS Pathog. 2012 Sep;8(9):e1002902. doi: 10.1371/journal.ppat.1002902. Epub 2012 Sep 6.

7.

Viral genome methylation differentially affects the ability of BZLF1 versus BRLF1 to activate Epstein-Barr virus lytic gene expression and viral replication.

Wille CK, Nawandar DM, Panfil AR, Ko MM, Hagemeier SR, Kenney SC.

J Virol. 2013 Jan;87(2):935-50. doi: 10.1128/JVI.01790-12. Epub 2012 Nov 7.

8.

The lytic phase of epstein-barr virus requires a viral genome with 5-methylcytosine residues in CpG sites.

Kalla M, Göbel C, Hammerschmidt W.

J Virol. 2012 Jan;86(1):447-58. doi: 10.1128/JVI.06314-11. Epub 2011 Oct 26.

9.

Shutoff of BZLF1 gene expression is necessary for immortalization of primary B cells by Epstein-Barr virus.

Yu X, McCarthy PJ, Wang Z, Gorlen DA, Mertz JE.

J Virol. 2012 Aug;86(15):8086-96. doi: 10.1128/JVI.00234-12. Epub 2012 May 23.

10.
11.

PARP1 restricts Epstein Barr Virus lytic reactivation by binding the BZLF1 promoter.

Lupey-Green LN, Moquin SA, Martin KA, McDevitt SM, Hulse M, Caruso LB, Pomerantz RT, Miranda JL, Tempera I.

Virology. 2017 Jul;507:220-230. doi: 10.1016/j.virol.2017.04.006. Epub 2017 Apr 26.

12.

Either ZEB1 or ZEB2/SIP1 can play a central role in regulating the Epstein-Barr virus latent-lytic switch in a cell-type-specific manner.

Ellis AL, Wang Z, Yu X, Mertz JE.

J Virol. 2010 Jun;84(12):6139-52. doi: 10.1128/JVI.02706-09. Epub 2010 Apr 7.

13.

Epstein-Barr virus utilizes Ikaros in regulating its latent-lytic switch in B cells.

Iempridee T, Reusch JA, Riching A, Johannsen EC, Dovat S, Kenney SC, Mertz JE.

J Virol. 2014 May;88(9):4811-27. doi: 10.1128/JVI.03706-13. Epub 2014 Feb 12.

14.

Identification of a novel element involved in regulation of the lytic switch BZLF1 gene promoter of Epstein-Barr virus.

Kraus RJ, Mirocha SJ, Stephany HM, Puchalski JR, Mertz JE.

J Virol. 2001 Jan;75(2):867-77.

15.

MicroRNA miR-BART20-5p stabilizes Epstein-Barr virus latency by directly targeting BZLF1 and BRLF1.

Jung YJ, Choi H, Kim H, Lee SK.

J Virol. 2014 Aug;88(16):9027-37. doi: 10.1128/JVI.00721-14. Epub 2014 Jun 4.

16.

Sumoylation of the Epstein-Barr virus BZLF1 protein inhibits its transcriptional activity and is regulated by the virus-encoded protein kinase.

Hagemeier SR, Dickerson SJ, Meng Q, Yu X, Mertz JE, Kenney SC.

J Virol. 2010 May;84(9):4383-94. doi: 10.1128/JVI.02369-09. Epub 2010 Feb 24.

17.

Valpromide Inhibits Lytic Cycle Reactivation of Epstein-Barr Virus.

Gorres KL, Daigle D, Mohanram S, McInerney GE, Lyons DE, Miller G.

MBio. 2016 Mar 1;7(2):e00113. doi: 10.1128/mBio.00113-16.

18.

5-hydroxymethylation of the EBV genome regulates the latent to lytic switch.

Wille CK, Nawandar DM, Henning AN, Ma S, Oetting KM, Lee D, Lambert P, Johannsen EC, Kenney SC.

Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):E7257-65. doi: 10.1073/pnas.1513432112. Epub 2015 Dec 9.

19.

Methylation profiling of Epstein-Barr virus immediate-early gene promoters, BZLF1 and BRLF1 in tumors of epithelial, NK- and B-cell origins.

Li L, Su X, Choi GC, Cao Y, Ambinder RF, Tao Q.

BMC Cancer. 2012 Mar 29;12:125. doi: 10.1186/1471-2407-12-125.

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