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Items: 1 to 20 of 108

1.

Expression profiling of uterine leiomyomata cytogenetic subgroups reveals distinct signatures in matched myometrium: transcriptional profilingof the t(12;14) and evidence in support of predisposing genetic heterogeneity.

Hodge JC, Kim TM, Dreyfuss JM, Somasundaram P, Christacos NC, Rousselle M, Quade BJ, Park PJ, Stewart EA, Morton CC.

Hum Mol Genet. 2012 May 15;21(10):2312-29. doi: 10.1093/hmg/dds051. Epub 2012 Feb 17.

2.

Identifying the molecular signature of the interstitial deletion 7q subgroup of uterine leiomyomata using a paired analysis.

Hodge JC, Park PJ, Dreyfuss JM, Assil-Kishawi I, Somasundaram P, Semere LG, Quade BJ, Lynch AM, Stewart EA, Morton CC.

Genes Chromosomes Cancer. 2009 Oct;48(10):865-85. doi: 10.1002/gcc.20692.

3.

Molecular and cytogenetic characterization of plexiform leiomyomata provide further evidence for genetic heterogeneity underlying uterine fibroids.

Hodge JC, Quade BJ, Rubin MA, Stewart EA, Dal Cin P, Morton CC.

Am J Pathol. 2008 May;172(5):1403-10. doi: 10.2353/ajpath.2008.071102. Epub 2008 Apr 10.

4.

HMGA2 expression in uterine leiomyomata and myometrium: quantitative analysis and tissue culture studies.

Gross KL, Neskey DM, Manchanda N, Weremowicz S, Kleinman MS, Nowak RA, Ligon AH, Rogalla P, Drechsler K, Bullerdiek J, Morton CC.

Genes Chromosomes Cancer. 2003 Sep;38(1):68-79.

PMID:
12874787
5.

Uterine leiomyomata with deletions of Ip represent a distinct cytogenetic subgroup associated with unusual histologic features.

Christacos NC, Quade BJ, Dal Cin P, Morton CC.

Genes Chromosomes Cancer. 2006 Mar;45(3):304-12.

PMID:
16320247
7.

Identification and characterization of novel human transcripts embedded within HMGA2 in t(12;14)(q15;q24.1) uterine leiomyoma.

Ingraham SE, Lynch RA, Surti U, Rutter JL, Buckler AJ, Khan SA, Menon AG, Lepont P.

Mutat Res. 2006 Dec 1;602(1-2):43-53. Epub 2006 Oct 12.

PMID:
17045619
8.

HMGA2 and the p19Arf-TP53-CDKN1A axis: a delicate balance in the growth of uterine leiomyomas.

Markowski DN, von Ahsen I, Nezhad MH, Wosniok W, Helmke BM, Bullerdiek J.

Genes Chromosomes Cancer. 2010 Aug;49(8):661-8. doi: 10.1002/gcc.20777.

PMID:
20544840
9.

Genetic heterogeneity among uterine leiomyomata: insights into malignant progression.

Hodge JC, Morton CC.

Hum Mol Genet. 2007 Apr 15;16 Spec No 1:R7-13. Review.

PMID:
17613550
10.

Uterine leiomyomata and decreased height: a common HMGA2 predisposition allele.

Hodge JC, T Cuenco K, Huyck KL, Somasundaram P, Panhuysen CI, Stewart EA, Morton CC.

Hum Genet. 2009 Apr;125(3):257-63. doi: 10.1007/s00439-008-0621-6. Epub 2009 Jan 9.

11.

The genetic heterogeneity of uterine leiomyomata.

Lobel MK, Somasundaram P, Morton CC.

Obstet Gynecol Clin North Am. 2006 Mar;33(1):13-39. Review.

PMID:
16504804
12.

Gene expression profiling of multiple leiomyomata uteri and matched normal tissue from a single patient.

Dimitrova IK, Richer JK, Rudolph MC, Spoelstra NS, Reno EM, Medina TM, Bradford AP.

Fertil Steril. 2009 Jun;91(6):2650-63. doi: 10.1016/j.fertnstert.2008.03.071. Epub 2008 Jul 30.

13.

Characteristic chromosome abnormalities, including rearrangements of 6p, del(7q), +12, and t(12;14), in 44 uterine leiomyomas.

Nilbert M, Heim S, Mandahl N, Flodérus UM, Willén H, Mitelman F.

Hum Genet. 1990 Oct;85(6):605-11.

PMID:
2227952
14.

Translocations in 7q22 define a critical region in uterine leiomyomata.

Sargent MS, Weremowicz S, Rein MS, Morton CC.

Cancer Genet Cytogenet. 1994 Oct;77(1):65-8.

PMID:
7923086
15.

Gene expression analysis reveals an angiogenic profile in uterine leiomyoma pseudocapsule.

Di Tommaso S, Massari S, Malvasi A, Bozzetti MP, Tinelli A.

Mol Hum Reprod. 2013 Jun;19(6):380-7. doi: 10.1093/molehr/gat007. Epub 2013 Jan 25.

PMID:
23355533
16.

Cytogenetic abnormalities in uterine leiomyomata.

Rein MS, Friedman AJ, Barbieri RL, Pavelka K, Fletcher JA, Morton CC.

Obstet Gynecol. 1991 Jun;77(6):923-6.

PMID:
2030869
17.

Overexpression of HMGA2 in uterine leiomyomas points to its general role for the pathogenesis of the disease.

Klemke M, Meyer A, Nezhad MH, Bartnitzke S, Drieschner N, Frantzen C, Schmidt EH, Belge G, Bullerdiek J.

Genes Chromosomes Cancer. 2009 Feb;48(2):171-8. doi: 10.1002/gcc.20627.

PMID:
18980243
18.

Molecular pathogenesis of uterine smooth muscle tumors from transcriptional profiling.

Quade BJ, Wang TY, Sornberger K, Dal Cin P, Mutter GL, Morton CC.

Genes Chromosomes Cancer. 2004 Jun;40(2):97-108.

PMID:
15101043
19.
20.

Physical mapping of distinct 7q22 deletions in uterine leiomyoma and analysis of a recently annotated 7q22 candidate gene.

Ptacek T, Song C, Walker CL, Sell SM.

Cancer Genet Cytogenet. 2007 Apr 15;174(2):116-20.

PMID:
17452252

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