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Items: 1 to 20 of 81

1.

The selective inhibition of nuclear PKCζ restores the effectiveness of chemotherapeutic agents in chemoresistant cells.

Rimessi A, Zecchini E, Siviero R, Giorgi C, Leo S, Rizzuto R, Pinton P.

Cell Cycle. 2012 Mar 1;11(5):1040-8. doi: 10.4161/cc.11.5.19520. Epub 2012 Mar 1.

2.

Atypical protein kinase C zeta as a target for chemosensitization of tumor cells.

Filomenko R, Poirson-Bichat F, Billerey C, Belon JP, Garrido C, Solary E, Bettaieb A.

Cancer Res. 2002 Mar 15;62(6):1815-21.

3.

Overexpression of protein kinase Czeta confers protection against antileukemic drugs by inhibiting the redox-dependent sphingomyelinase activation.

Bezombes C, de Thonel A, Apostolou A, Louat T, Jaffrézou JP, Laurent G, Quillet-Mary A.

Mol Pharmacol. 2002 Dec;62(6):1446-55.

4.

Aspirin prevention of NMDA-induced neuronal death by direct protein kinase Czeta inhibition.

Crisanti P, Leon A, Lim DM, Omri B.

J Neurochem. 2005 Jun;93(6):1587-93.

5.

Parthenolide sensitizes ultraviolet (UV)-B-induced apoptosis via protein kinase C-dependent pathways.

Won YK, Ong CN, Shen HM.

Carcinogenesis. 2005 Dec;26(12):2149-56. Epub 2005 Jul 28.

PMID:
16051639
6.

PKCzeta protects against UV-C-induced apoptosis by inhibiting acid sphingomyelinase-dependent ceramide production.

Charruyer A, Jean C, Colomba A, Jaffrézou JP, Quillet-Mary A, Laurent G, Bezombes C.

Biochem J. 2007 Jul 1;405(1):77-83.

7.
8.

Protein kinase C ζ regulates survivin expression and inhibits apoptosis in colon cancer.

Umemori Y, Kuribayashi K, Nirasawa S, Kondoh T, Tanaka M, Kobayashi D, Watanabe N.

Int J Oncol. 2014 Sep;45(3):1043-50. doi: 10.3892/ijo.2014.2489. Epub 2014 Jun 10.

PMID:
24920238
9.

p62 binding to protein kinase C ζ regulates tumor necrosis factor α-induced apoptotic pathway in endothelial cells.

Kim GY, Nigro P, Fujiwara K, Abe J, Berk BC.

Arterioscler Thromb Vasc Biol. 2012 Dec;32(12):2974-80. doi: 10.1161/ATVBAHA.112.300054. Epub 2012 Sep 27.

10.

Protein kinase C ζ is a positive modulator of canonical Wnt signaling pathway in tumoral colon cell lines.

Luna-Ulloa LB, Hernández-Maqueda JG, Santoyo-Ramos P, Castañeda-Patlán MC, Robles-Flores M.

Carcinogenesis. 2011 Nov;32(11):1615-24. doi: 10.1093/carcin/bgr190. Epub 2011 Aug 22.

PMID:
21859831
11.

Role of protein kinase Czeta in thrombin-induced RhoA activation and inter-endothelial gap formation of human dermal microvessel endothelial cell monolayers.

Minshall RD, Vandenbroucke EE, Holinstat M, Place AT, Tiruppathi C, Vogel SM, van Nieuw Amerongen GP, Mehta D, Malik AB.

Microvasc Res. 2010 Sep;80(2):240-9. doi: 10.1016/j.mvr.2010.04.007. Epub 2010 Apr 24.

12.
14.

Protein kinase C zeta mediates epidermal growth factor-induced growth of head and neck tumor cells by regulating mitogen-activated protein kinase.

Cohen EE, Lingen MW, Zhu B, Zhu H, Straza MW, Pierce C, Martin LE, Rosner MR.

Cancer Res. 2006 Jun 15;66(12):6296-303.

15.

Activation of atypical protein kinase C zeta by caspase processing and degradation by the ubiquitin-proteasome system.

Smith L, Chen L, Reyland ME, DeVries TA, Talanian RV, Omura S, Smith JB.

J Biol Chem. 2000 Dec 22;275(51):40620-7.

16.

Atypical protein kinase C zeta exhibits a proapoptotic function in ovarian cancer.

Nazarenko I, Jenny M, Keil J, Gieseler C, Weisshaupt K, Sehouli J, Legewie S, Herbst L, Weichert W, Darb-Esfahani S, Dietel M, Schäfer R, Ueberall F, Sers C.

Mol Cancer Res. 2010 Jun;8(6):919-34. doi: 10.1158/1541-7786.MCR-09-0358. Epub 2010 May 25.

17.

Protein kinase C-zeta mediates retinal degeneration in response to TNF.

Liang H, Baudouin C, Behar-Cohen F, Crisanti P, Omri B.

J Neuroimmunol. 2007 Feb;183(1-2):104-10. Epub 2007 Jan 3.

PMID:
17207538
18.

A small molecule inhibitor of atypical protein kinase C signaling inhibits pancreatic cancer cell transformed growth and invasion.

Butler AM, Scotti Buzhardt ML, Erdogan E, Li S, Inman KS, Fields AP, Murray NR.

Oncotarget. 2015 Jun 20;6(17):15297-310.

19.
20.

Protein kinase Czeta activation mediates glucagon-like peptide-1-induced pancreatic beta-cell proliferation.

Buteau J, Foisy S, Rhodes CJ, Carpenter L, Biden TJ, Prentki M.

Diabetes. 2001 Oct;50(10):2237-43.

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