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Items: 1 to 20 of 132

1.

Expression of hypoxia-inducible factor-1α, vascular endothelial growth factor, and matrix metalloproteinases 1, 3, and 9 in hypertrophied ligamentum flavum.

Lakemeier S, Schofer MD, Foltz L, Schmid R, Efe T, Rohlfs J, Fuchs-Winkelmann S, El-Zayat BF, Paletta JR, Foelsch C.

J Spinal Disord Tech. 2013 Oct;26(7):400-6. doi: 10.1097/BSD.0b013e3182495b88.

PMID:
22323068
2.

Increased expression of CD44 in hypertrophied ligamentum flavum and relevance of splice variants CD44v5 and CD44v6.

Lakemeier S, Schmid R, Foltz L, Rohlfs J, Fuchs-Winkelmann S, Efe T, Foelsch C, Paletta JR.

Acta Neurochir (Wien). 2012 Feb;154(2):359-65; discussion 365. doi: 10.1007/s00701-011-1206-z. Epub 2011 Nov 4.

PMID:
22052472
3.

Is platelet-derived growth factor-BB expression proportional to fibrosis in the hypertrophied lumber ligamentum flavum?

Zhang Y, Chen J, Zhong ZM, Yang D, Zhu Q.

Spine (Phila Pa 1976). 2010 Dec 1;35(25):E1479-86. doi: 10.1097/BRS.0b013e3181f3d2df.

PMID:
21102276
4.

Factors associated with the thickness of the ligamentum flavum: is ligamentum flavum thickening due to hypertrophy or buckling?

Altinkaya N, Yildirim T, Demir S, Alkan O, Sarica FB.

Spine (Phila Pa 1976). 2011 Jul 15;36(16):E1093-7. doi: 10.1097/BRS.0b013e318203e2b5.

PMID:
21343862
5.

Hypertrophy of ligamentum flavum in lumbar spine stenosis associated with the increased expression of connective tissue growth factor.

Zhong ZM, Zha DS, Xiao WD, Wu SH, Wu Q, Zhang Y, Liu FQ, Chen JT.

J Orthop Res. 2011 Oct;29(10):1592-7. doi: 10.1002/jor.21431. Epub 2011 Apr 11.

6.

Cellularity and cartilage matrix increased in hypertrophied ligamentum flavum: histopathological analysis focusing on the mechanical stress and bone morphogenetic protein signaling.

Shafaq N, Suzuki A, Terai H, Wakitani S, Nakamura H.

J Spinal Disord Tech. 2012 Apr;25(2):107-15. doi: 10.1097/BSD.0b013e31820bb76e.

PMID:
21430570
7.

The increased expression of matrix metalloproteinases associated with elastin degradation and fibrosis of the ligamentum flavum in patients with lumbar spinal stenosis.

Park JB, Kong CG, Suhl KH, Chang ED, Riew KD.

Clin Orthop Surg. 2009 Jun;1(2):81-9. doi: 10.4055/cios.2009.1.2.81. Epub 2009 May 27.

8.

Pathomechanism of loss of elasticity and hypertrophy of lumbar ligamentum flavum in elderly patients with lumbar spinal canal stenosis.

Kosaka H, Sairyo K, Biyani A, Leaman D, Yeasting R, Higashino K, Sakai T, Katoh S, Sano T, Goel VK, Yasui N.

Spine (Phila Pa 1976). 2007 Dec 1;32(25):2805-11. doi: 10.1097/BRS.0b013e31815b650f.

PMID:
18246001
9.

Increased expression of vascular endothelial growth factor is associated with hypertrophic ligamentum flavum in lumbar spinal canal stenosis.

Jirathanathornnukul N, Limthongkul W, Yingsakmongkol W, Singhatanadgige W, Parkpian V, Honsawek S.

J Investig Med. 2016 Apr;64(4):882-7. doi: 10.1136/jim-2015-000024. Epub 2016 Mar 8.

PMID:
26956787
10.

Hypertrophy and Fibrosis of the Ligamentum Flavum in Lumbar Spinal Stenosis is Associated With Increased Expression of LPA and LPAR1.

Zhang K, Sun W, Liu XY, Zhao CQ, Li H, Sun XJ, You-Zhuan X, Ding W, Zhao J.

Clin Spine Surg. 2017 Apr;30(3):E189-E191. doi: 10.1097/BSD.0000000000000048.

PMID:
28323698
11.

Chondrogenic and fibrotic process in the ligamentum flavum of patients with lumbar spinal canal stenosis.

Yabe Y, Hagiwara Y, Ando A, Tsuchiya M, Minowa T, Takemura T, Honda M, Hatori K, Sonofuchi K, Kanazawa K, Koide M, Sekiguchi T, Itoi E.

Spine (Phila Pa 1976). 2015 Apr 1;40(7):429-35. doi: 10.1097/BRS.0000000000000795.

PMID:
25627290
12.

[Over-expression of platelet-derived growth factor-BB in degenerative hypertrophied ligamentum flavum].

Zhang Y, Xu XM, Wu SP, Xia XZ, Li CT, Dedg CL, Chen JT.

Nan Fang Yi Ke Da Xue Xue Bao. 2011 Jun;31(7):1268-72. Chinese.

PMID:
21764712
13.

Hypertrophy of the ligamentum flavum in lumbar spinal canal stenosis is associated with increased bFGF expression.

Honsawek S, Poonpukdee J, Chalermpanpipat C, Payungporn S, Limthongkul W, Yingsakmongkol W, Thanakit V, Parkpian V.

Int Orthop. 2013 Jul;37(7):1387-92. doi: 10.1007/s00264-013-1864-y. Epub 2013 Mar 22.

14.

Pathomechanism of ligamentum flavum hypertrophy: a multidisciplinary investigation based on clinical, biomechanical, histologic, and biologic assessments.

Sairyo K, Biyani A, Goel V, Leaman D, Booth R Jr, Thomas J, Gehling D, Vishnubhotla L, Long R, Ebraheim N.

Spine (Phila Pa 1976). 2005 Dec 1;30(23):2649-56.

PMID:
16319751
15.

Lumbar ligamentum flavum hypertrophy is due to accumulation of inflammation-related scar tissue.

Sairyo K, Biyani A, Goel VK, Leaman DW, Booth R Jr, Thomas J, Ebraheim NA, Cowgill IA, Mohan SE.

Spine (Phila Pa 1976). 2007 May 15;32(11):E340-7.

PMID:
17495768
16.
17.

The Mechanism of Ligamentum Flavum Hypertrophy: Introducing Angiogenesis as a Critical Link That Couples Mechanical Stress and Hypertrophy.

Hur JW, Kim BJ, Park JH, Kim JH, Park YK, Kwon TH, Moon HJ.

Neurosurgery. 2015 Aug;77(2):274-81; discussion 281-2. doi: 10.1227/NEU.0000000000000755.

PMID:
25850600
18.

Matrix metalloproteinase-3 on ligamentum flavum in degenerative lumbar spondylolisthesis.

Oh IS, Ha KY.

Spine (Phila Pa 1976). 2009 Jul 15;34(16):E552-7. doi: 10.1097/BRS.0b013e3181aa0232.

PMID:
19770597
19.

Expression of the JAK/STAT signaling pathway in the ligamentum flavum of patients with lumbar spinal canal stenosis.

Yamahata H, Osuka K, Aoyama T, Yasuda M, Tokimura H, Arita K, Takayasu M.

J Orthop Sci. 2017 Mar;22(2):190-196. doi: 10.1016/j.jos.2016.11.005. Epub 2016 Nov 23.

PMID:
27889106
20.

MiR-21 promotes fibrosis and hypertrophy of ligamentum flavum in lumbar spinal canal stenosis by activating IL-6 expression.

Sun C, Tian J, Liu X, Guan G.

Biochem Biophys Res Commun. 2017 Aug 26;490(3):1106-1111. doi: 10.1016/j.bbrc.2017.06.182. Epub 2017 Jun 29.

PMID:
28669725

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