Similar articles for PMID: 22319457

Year	Number of Results
2000	1
2001	1
2002	1
2003	2
2004	1
2005	1
2006	6
2007	7
2008	4
2009	11
2010	6
2011	5
2012	9
2013	13
2014	12
2015	7
2016	10
2017	8
2018	10
2019	1
2020	1
2021	2
2022	1
2023	3
2024	0

1

Down-regulating sphingolipid synthesis increases yeast lifespan.

Huang X, Liu J, Dickson RC. Huang X, et al. PLoS Genet. 2012 Feb;8(2):e1002493. doi: 10.1371/journal.pgen.1002493. Epub 2012 Feb 2. PLoS Genet. 2012. PMID: 22319457 Free PMC article.

2

The protein kinase Sch9 is a key regulator of sphingolipid metabolism in Saccharomyces cerevisiae.

Swinnen E, Wilms T, Idkowiak-Baldys J, Smets B, De Snijder P, Accardo S, Ghillebert R, Thevissen K, Cammue B, De Vos D, Bielawski J, Hannun YA, Winderickx J. Swinnen E, et al. Mol Biol Cell. 2014 Jan;25(1):196-211. doi: 10.1091/mbc.E13-06-0340. Epub 2013 Nov 6. Mol Biol Cell. 2014. PMID: 24196832 Free PMC article.

3

Molecular mechanisms linking the evolutionary conserved TORC1-Sch9 nutrient signalling branch to lifespan regulation in Saccharomyces cerevisiae.

Swinnen E, Ghillebert R, Wilms T, Winderickx J. Swinnen E, et al. FEMS Yeast Res. 2014 Feb;14(1):17-32. doi: 10.1111/1567-1364.12097. Epub 2013 Oct 11. FEMS Yeast Res. 2014. PMID: 24102693 Review.

4

Caffeine extends yeast lifespan by targeting TORC1.

Wanke V, Cameroni E, Uotila A, Piccolis M, Urban J, Loewith R, De Virgilio C. Wanke V, et al. Mol Microbiol. 2008 Jul;69(1):277-85. doi: 10.1111/j.1365-2958.2008.06292.x. Epub 2008 May 26. Mol Microbiol. 2008. PMID: 18513215 Free article.

5

Reducing sphingolipid synthesis orchestrates global changes to extend yeast lifespan.

Liu J, Huang X, Withers BR, Blalock E, Liu K, Dickson RC. Liu J, et al. Aging Cell. 2013 Oct;12(5):833-41. doi: 10.1111/acel.12107. Epub 2013 Jul 8. Aging Cell. 2013. PMID: 23725375 Free PMC article.

6

Reducing signs of aging and increasing lifespan by drug synergy.

Huang X, Liu J, Withers BR, Samide AJ, Leggas M, Dickson RC. Huang X, et al. Aging Cell. 2013 Aug;12(4):652-60. doi: 10.1111/acel.12090. Epub 2013 May 15. Aging Cell. 2013. PMID: 23601176 Free PMC article.

7

Tor1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension.

Wei M, Fabrizio P, Madia F, Hu J, Ge H, Li LM, Longo VD. Wei M, et al. PLoS Genet. 2009 May;5(5):e1000467. doi: 10.1371/journal.pgen.1000467. Epub 2009 May 8. PLoS Genet. 2009. PMID: 19424415 Free PMC article.

8

Protection against cisplatin in calorie-restricted Saccharomyces cerevisiae is mediated by the nutrient-sensor proteins Ras2, Tor1, or Sch9 through its target glutathione.

Mariani D, Castro FA, Almeida LG, Fonseca FL, Pereira MD. Mariani D, et al. FEMS Yeast Res. 2014 Dec;14(8):1147-59. doi: 10.1111/1567-1364.12214. Epub 2014 Oct 21. FEMS Yeast Res. 2014. PMID: 25238629

9

Orm family proteins mediate sphingolipid homeostasis.

Breslow DK, Collins SR, Bodenmiller B, Aebersold R, Simons K, Shevchenko A, Ejsing CS, Weissman JS. Breslow DK, et al. Nature. 2010 Feb 25;463(7284):1048-53. doi: 10.1038/nature08787. Nature. 2010. PMID: 20182505 Free PMC article.

10

Sphingolipid signalling mediates mitochondrial dysfunctions and reduced chronological lifespan in the yeast model of Niemann-Pick type C1.

Vilaça R, Silva E, Nadais A, Teixeira V, Matmati N, Gaifem J, Hannun YA, Sá Miranda MC, Costa V. Vilaça R, et al. Mol Microbiol. 2014 Feb;91(3):438-51. doi: 10.1111/mmi.12470. Epub 2013 Dec 12. Mol Microbiol. 2014. PMID: 24286211 Free PMC article.

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