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Items: 1 to 20 of 97

1.

Evaluation of direct in vivo gene transfer in an equine metacarpal IV ostectomy model using an adenoviral vector encoding the bone morphogenetic protein-2 and protein-7 gene.

Southwood LL, Kawcak CE, Hidaka C, McIlwraith CW, Werpy N, Macleay J, Frisbie DD.

Vet Surg. 2012 Apr;41(3):345-54. doi: 10.1111/j.1532-950X.2011.00947.x. Epub 2012 Feb 6.

PMID:
22308976
2.

Osteogenic gene regulation and relative acceleration of healing by adenoviral-mediated transfer of human BMP-2 or -6 in equine osteotomy and ostectomy models.

Ishihara A, Shields KM, Litsky AS, Mattoon JS, Weisbrode SE, Bartlett JS, Bertone AL.

J Orthop Res. 2008 Jun;26(6):764-71. doi: 10.1002/jor.20585.

3.

Direct delayed human adenoviral BMP-2 or BMP-6 gene therapy for bone and cartilage regeneration in a pony osteochondral model.

Menendez MI, Clark DJ, Carlton M, Flanigan DC, Jia G, Sammet S, Weisbrode SE, Knopp MV, Bertone AL.

Osteoarthritis Cartilage. 2011 Aug;19(8):1066-75. doi: 10.1016/j.joca.2011.05.007. Epub 2011 Jun 2.

4.

Adenoviral-mediated transfer of human BMP-6 gene accelerates healing in a rabbit ulnar osteotomy model.

Bertone AL, Pittman DD, Bouxsein ML, Li J, Clancy B, Seeherman HJ.

J Orthop Res. 2004 Nov;22(6):1261-70.

5.

Comparative efficacy of dermal fibroblast-mediated and direct adenoviral bone morphogenetic protein-2 gene therapy for bone regeneration in an equine rib model.

Ishihara A, Zekas LJ, Weisbrode SE, Bertone AL.

Gene Ther. 2010 Jun;17(6):733-44. doi: 10.1038/gt.2010.13. Epub 2010 Mar 11.

PMID:
20220786
6.

Assessment of the mineral density and mineral content of the equine third metacarpal and first phalanx bone by dual energy x-ray absorptiometry.

Tóth P, Horváth C, Ferencz V, Nagy K, Gligor N, Szenci O, Bodó G.

Acta Vet Hung. 2010 Sep;58(3):317-29. doi: 10.1556/AVet.58.2010.3.5.

PMID:
20713323
7.

Direct percutaneous gene delivery to enhance healing of segmental bone defects.

Betz OB, Betz VM, Nazarian A, Pilapil CG, Vrahas MS, Bouxsein ML, Gerstenfeld LC, Einhorn TA, Evans CH.

J Bone Joint Surg Am. 2006 Feb;88(2):355-65.

PMID:
16452748
8.

Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer.

Steinert AF, Proffen B, Kunz M, Hendrich C, Ghivizzani SC, Nöth U, Rethwilm A, Eulert J, Evans CH.

Arthritis Res Ther. 2009;11(5):R148. doi: 10.1186/ar2822. Epub 2009 Oct 2.

9.

Healing of large segmental bone defects induced by expedited bone morphogenetic protein-2 gene-activated, syngeneic muscle grafts.

Betz OB, Betz VM, Abdulazim A, Penzkofer R, Schmitt B, Schröder C, Augat P, Jansson V, Müller PE.

Hum Gene Ther. 2009 Dec;20(12):1589-96. doi: 10.1089/hum.2009.037.

PMID:
19572783
10.

Synergistic effect of bone morphogenetic proteins 2 and 7 by ex vivo gene therapy in a rat spinal fusion model.

Kaito T, Johnson J, Ellerman J, Tian H, Aydogan M, Chatsrinopkun M, Ngo S, Choi C, Wang JC.

J Bone Joint Surg Am. 2013 Sep 4;95(17):1612-9. doi: 10.2106/JBJS.L.01396.

PMID:
24005203
11.

Evaluation of Ad-BMP-2 for enhancing fracture healing in an infected defect fracture rabbit model.

Southwood LL, Frisbie DD, Kawcak CE, Ghivizzani SC, Evans CH, McIlwraith CW.

J Orthop Res. 2004 Jan;22(1):66-72.

12.

Influence of short-term adenoviral vector and prolonged lentiviral vector mediated bone morphogenetic protein-2 expression on the quality of bone repair in a rat femoral defect model.

Virk MS, Conduah A, Park SH, Liu N, Sugiyama O, Cuomo A, Kang C, Lieberman JR.

Bone. 2008 May;42(5):921-31. doi: 10.1016/j.bone.2007.12.216. Epub 2008 Jan 5.

PMID:
18295562
13.

Bone regeneration in critical size defects by cell-mediated BMP-2 gene transfer: a comparison of adenoviral vectors and liposomes.

Park J, Ries J, Gelse K, Kloss F, von der Mark K, Wiltfang J, Neukam FW, Schneider H.

Gene Ther. 2003 Jul;10(13):1089-98.

PMID:
12808439
14.

Effect of BMP-2 gene transfer on bone healing in sheep.

Egermann M, Lill CA, Griesbeck K, Evans CH, Robbins PD, Schneider E, Baltzer AW.

Gene Ther. 2006 Sep;13(17):1290-9. Epub 2006 Apr 27.

PMID:
16642029
15.

The effects of lentiviral gene therapy with bone morphogenetic protein-2-producing bone marrow cells on spinal fusion in rats.

Miyazaki M, Sugiyama O, Tow B, Zou J, Morishita Y, Wei F, Napoli A, Sintuu C, Lieberman JR, Wang JC.

J Spinal Disord Tech. 2008 Jul;21(5):372-9. doi: 10.1097/BSD.0b013e31814cf51d.

PMID:
18600149
16.

Healing of segmental bone defects by direct percutaneous gene delivery: effect of vector dose.

Betz VM, Betz OB, Glatt V, Gerstenfeld LC, Einhorn TA, Bouxsein ML, Vrahas MS, Evans CH.

Hum Gene Ther. 2007 Oct;18(10):907-15.

PMID:
17910523
17.

Dermal fibroblast-mediated BMP2 therapy to accelerate bone healing in an equine osteotomy model.

Ishihara A, Zekas LJ, Litsky AS, Weisbrode SE, Bertone AL.

J Orthop Res. 2010 Mar;28(3):403-11. doi: 10.1002/jor.20978.

18.

Angiopoiesis and bone regeneration via co-expression of the hVEGF and hBMP genes from an adeno-associated viral vector in vitro and in vivo.

Zhang C, Wang KZ, Qiang H, Tang YL, Li Q, Li M, Dang XQ.

Acta Pharmacol Sin. 2010 Jul;31(7):821-30. doi: 10.1038/aps.2010.67. Epub 2010 Jun 28.

19.

Effects of a novel hydrogel on equine bone healing: a pilot study.

Cohen JM, Southwood LL, Engiles J, Leitch M, Nunamaker DM.

Vet Comp Orthop Traumatol. 2012;25(3):184-91. doi: 10.3415/VCOT-11-01-0006. Epub 2012 Feb 27.

PMID:
22366873
20.

Large-scale bicortical skull bone regeneration using ex vivo replication-defective adenoviral-mediated bone morphogenetic protein-2 gene-transferred bone marrow stromal cells and composite biomaterials.

Chang SC, Lin TM, Chung HY, Chen PK, Lin FH, Lou J, Jeng LB.

Neurosurgery. 2009 Dec;65(6 Suppl):75-81; discussion 81-3. doi: 10.1227/01.NEU.0000345947.33730.91.

PMID:
19935005

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