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Items: 1 to 20 of 87

1.

Global kinetic analysis of proteolysis via quantitative targeted proteomics.

Agard NJ, Mahrus S, Trinidad JC, Lynn A, Burlingame AL, Wells JA.

Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):1913-8. doi: 10.1073/pnas.1117158109. Epub 2012 Jan 23.

2.

Inflammatory stimuli regulate caspase substrate profiles.

Agard NJ, Maltby D, Wells JA.

Mol Cell Proteomics. 2010 May;9(5):880-93. doi: 10.1074/mcp.M900528-MCP200. Epub 2010 Feb 20.

3.

Complementary proteomic tools for the dissection of apoptotic proteolysis events.

Pham VC, Pitti R, Anania VG, Bakalarski CE, Bustos D, Jhunjhunwala S, Phung QT, Yu K, Forrest WF, Kirkpatrick DS, Ashkenazi A, Lill JR.

J Proteome Res. 2012 May 4;11(5):2947-54. doi: 10.1021/pr300035k. Epub 2012 Mar 29.

PMID:
22432722
4.

Quantitative MS-based enzymology of caspases reveals distinct protein substrate specificities, hierarchies, and cellular roles.

Julien O, Zhuang M, Wiita AP, O'Donoghue AJ, Knudsen GM, Craik CS, Wells JA.

Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):E2001-10. doi: 10.1073/pnas.1524900113. Epub 2016 Mar 22.

5.

Complementary methods for the identification of substrates of proteolysis.

Pham VC, Anania VG, Phung QT, Lill JR.

Methods Enzymol. 2014;544:359-80. doi: 10.1016/B978-0-12-417158-9.00014-5.

PMID:
24974297
6.

Specific proteolysis of the A-kinase-anchoring protein 149 at the Asp582 residue by caspases during apoptosis.

Yoo H, Cha HJ, Lee J, Yu EO, Bae S, Jung JH, Sohn I, Lee SJ, Yang KH, Woo SH, Seo SK, Park IC, Kim CS, Jin YW, Ahn SK.

Oncol Rep. 2008 Jun;19(6):1577-82.

PMID:
18497968
7.

Global analysis of cellular proteolysis by selective enzymatic labeling of protein N-termini.

Wiita AP, Seaman JE, Wells JA.

Methods Enzymol. 2014;544:327-58. doi: 10.1016/B978-0-12-417158-9.00013-3.

8.
9.

The DegraBase: a database of proteolysis in healthy and apoptotic human cells.

Crawford ED, Seaman JE, Agard N, Hsu GW, Julien O, Mahrus S, Nguyen H, Shimbo K, Yoshihara HA, Zhuang M, Chalkley RJ, Wells JA.

Mol Cell Proteomics. 2013 Mar;12(3):813-24. doi: 10.1074/mcp.O112.024372. Epub 2012 Dec 20.

10.

Caspase-specific and nonspecific in vivo protein processing during Fas-induced apoptosis.

Van Damme P, Martens L, Van Damme J, Hugelier K, Staes A, Vandekerckhove J, Gevaert K.

Nat Methods. 2005 Oct;2(10):771-7.

PMID:
16179924
13.

Staurosporine-induced apoptosis in cardiomyocytes: A potential role of caspase-3.

Yue TL, Wang C, Romanic AM, Kikly K, Keller P, DeWolf WE Jr, Hart TK, Thomas HC, Storer B, Gu JL, Wang X, Feuerstein GZ.

J Mol Cell Cardiol. 1998 Mar;30(3):495-507.

PMID:
9515027
14.
15.
16.

Silibinin triggers apoptotic signaling pathways and autophagic survival response in human colon adenocarcinoma cells and their derived metastatic cells.

Kauntz H, Bousserouel S, Gossé F, Raul F.

Apoptosis. 2011 Oct;16(10):1042-53. doi: 10.1007/s10495-011-0631-z.

PMID:
21779837
17.

Biomarkers of breast cancer apoptosis induced by chemotherapy and TRAIL.

Leong S, McKay MJ, Christopherson RI, Baxter RC.

J Proteome Res. 2012 Feb 3;11(2):1240-50. doi: 10.1021/pr200935y. Epub 2011 Dec 14.

PMID:
22133146
18.
19.

The alkylphospholipid perifosine induces apoptosis of human lung cancer cells requiring inhibition of Akt and activation of the extrinsic apoptotic pathway.

Elrod HA, Lin YD, Yue P, Wang X, Lonial S, Khuri FR, Sun SY.

Mol Cancer Ther. 2007 Jul;6(7):2029-38. Epub 2007 Jun 29.

20.

Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand.

Varfolomeev E, Maecker H, Sharp D, Lawrence D, Renz M, Vucic D, Ashkenazi A.

J Biol Chem. 2005 Dec 9;280(49):40599-608. Epub 2005 Oct 15.

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