Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 124

1.

Contribution of host nucleoporin 62 in HIV-1 integrase chromatin association and viral DNA integration.

Ao Z, Jayappa KD, Wang B, Zheng Y, Wang X, Peng J, Yao X.

J Biol Chem. 2012 Mar 23;287(13):10544-55. doi: 10.1074/jbc.M111.317057. Epub 2012 Feb 3.

2.

Peptides derived from the HIV-1 integrase promote HIV-1 infection and multi-integration of viral cDNA in LEDGF/p75-knockdown cells.

Levin A, Hayouka Z, Friedler A, Loyter A.

Virol J. 2010 Aug 2;7:177. doi: 10.1186/1743-422X-7-177.

3.

New class of HIV-1 integrase (IN) inhibitors with a dual mode of action.

Tsiang M, Jones GS, Niedziela-Majka A, Kan E, Lansdon EB, Huang W, Hung M, Samuel D, Novikov N, Xu Y, Mitchell M, Guo H, Babaoglu K, Liu X, Geleziunas R, Sakowicz R.

J Biol Chem. 2012 Jun 15;287(25):21189-203. doi: 10.1074/jbc.M112.347534. Epub 2012 Apr 25.

4.

Differential effects of human immunodeficiency virus type 1 capsid and cellular factors nucleoporin 153 and LEDGF/p75 on the efficiency and specificity of viral DNA integration.

Koh Y, Wu X, Ferris AL, Matreyek KA, Smith SJ, Lee K, KewalRamani VN, Hughes SH, Engelman A.

J Virol. 2013 Jan;87(1):648-58. doi: 10.1128/JVI.01148-12. Epub 2012 Oct 24.

5.
6.

An essential role for LEDGF/p75 in HIV integration.

Llano M, Saenz DT, Meehan A, Wongthida P, Peretz M, Walker WH, Teo W, Poeschla EM.

Science. 2006 Oct 20;314(5798):461-4. Epub 2006 Sep 7.

7.

Structural and functional role of INI1 and LEDGF in the HIV-1 preintegration complex.

Maillot B, Lévy N, Eiler S, Crucifix C, Granger F, Richert L, Didier P, Godet J, Pradeau-Aubreton K, Emiliani S, Nazabal A, Lesbats P, Parissi V, Mely Y, Moras D, Schultz P, Ruff M.

PLoS One. 2013 Apr 11;8(4):e60734. doi: 10.1371/journal.pone.0060734. Print 2013.

8.

Zinc finger endonuclease targeting PSIP1 inhibits HIV-1 integration.

Badia R, Pauls E, Riveira-Munoz E, Clotet B, Esté JA, Ballana E.

Antimicrob Agents Chemother. 2014 Aug;58(8):4318-27. doi: 10.1128/AAC.02690-14. Epub 2014 May 12.

9.

A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin.

Sowd GA, Serrao E, Wang H, Wang W, Fadel HJ, Poeschla EM, Engelman AN.

Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):E1054-63. doi: 10.1073/pnas.1524213113. Epub 2016 Feb 8.

10.

Integrase mutants defective for interaction with LEDGF/p75 are impaired in chromosome tethering and HIV-1 replication.

Emiliani S, Mousnier A, Busschots K, Maroun M, Van Maele B, Tempé D, Vandekerckhove L, Moisant F, Ben-Slama L, Witvrouw M, Christ F, Rain JC, Dargemont C, Debyser Z, Benarous R.

J Biol Chem. 2005 Jul 8;280(27):25517-23. Epub 2005 Apr 25.

11.

LEDGIN-mediated Inhibition of Integrase-LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV.

Vranckx LS, Demeulemeester J, Saleh S, Boll A, Vansant G, Schrijvers R, Weydert C, Battivelli E, Verdin E, Cereseto A, Christ F, Gijsbers R, Debyser Z.

EBioMedicine. 2016 Jun;8:248-264. doi: 10.1016/j.ebiom.2016.04.039. Epub 2016 May 13.

12.

Nuclear architecture dictates HIV-1 integration site selection.

Marini B, Kertesz-Farkas A, Ali H, Lucic B, Lisek K, Manganaro L, Pongor S, Luzzati R, Recchia A, Mavilio F, Giacca M, Lusic M.

Nature. 2015 May 14;521(7551):227-31. doi: 10.1038/nature14226. Epub 2015 Mar 2.

PMID:
25731161
13.

Transient and stable knockdown of the integrase cofactor LEDGF/p75 reveals its role in the replication cycle of human immunodeficiency virus.

Vandekerckhove L, Christ F, Van Maele B, De Rijck J, Gijsbers R, Van den Haute C, Witvrouw M, Debyser Z.

J Virol. 2006 Feb;80(4):1886-96.

14.

LEDGF/p75 proteins with alternative chromatin tethers are functional HIV-1 cofactors.

Meehan AM, Saenz DT, Morrison JH, Garcia-Rivera JA, Peretz M, Llano M, Poeschla EM.

PLoS Pathog. 2009 Jul;5(7):e1000522. doi: 10.1371/journal.ppat.1000522. Epub 2009 Jul 17.

15.

Multimode, cooperative mechanism of action of allosteric HIV-1 integrase inhibitors.

Kessl JJ, Jena N, Koh Y, Taskent-Sezgin H, Slaughter A, Feng L, de Silva S, Wu L, Le Grice SF, Engelman A, Fuchs JR, Kvaratskhelia M.

J Biol Chem. 2012 May 11;287(20):16801-11. doi: 10.1074/jbc.M112.354373. Epub 2012 Mar 21.

16.

A role for LEDGF/p75 in targeting HIV DNA integration.

Ciuffi A, Llano M, Poeschla E, Hoffmann C, Leipzig J, Shinn P, Ecker JR, Bushman F.

Nat Med. 2005 Dec;11(12):1287-9. Epub 2005 Nov 27.

PMID:
16311605
17.

Implication of serine residues 271, 273, and 275 in the human immunodeficiency virus type 1 cofactor activity of lens epithelium-derived growth factor/p75.

Garcia-Rivera JA, Bueno MT, Morales E, Kugelman JR, Rodriguez DF, Llano M.

J Virol. 2010 Jan;84(2):740-52. doi: 10.1128/JVI.01043-09. Epub 2009 Nov 4.

18.

Role of the PWWP domain of lens epithelium-derived growth factor (LEDGF)/p75 cofactor in lentiviral integration targeting.

Gijsbers R, Vets S, De Rijck J, Ocwieja KE, Ronen K, Malani N, Bushman FD, Debyser Z.

J Biol Chem. 2011 Dec 2;286(48):41812-25. doi: 10.1074/jbc.M111.255711. Epub 2011 Oct 10. Retraction in: J Biol Chem. 2018 Jan 5;293(1):114.

19.

Virus evolution reveals an exclusive role for LEDGF/p75 in chromosomal tethering of HIV.

Hombrouck A, De Rijck J, Hendrix J, Vandekerckhove L, Voet A, De Maeyer M, Witvrouw M, Engelborghs Y, Christ F, Gijsbers R, Debyser Z.

PLoS Pathog. 2007 Mar;3(3):e47.

20.

Host factors for retroviral integration site selection.

Debyser Z, Christ F, De Rijck J, Gijsbers R.

Trends Biochem Sci. 2015 Feb;40(2):108-16. doi: 10.1016/j.tibs.2014.12.001. Epub 2014 Dec 31. Review.

PMID:
25555456

Supplemental Content

Support Center