Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 121

1.

Evolutionary and functional analyses of the interaction between the myeloid restriction factor SAMHD1 and the lentiviral Vpx protein.

Laguette N, Rahm N, Sobhian B, Chable-Bessia C, Münch J, Snoeck J, Sauter D, Switzer WM, Heneine W, Kirchhoff F, Delsuc F, Telenti A, Benkirane M.

Cell Host Microbe. 2012 Feb 16;11(2):205-17. doi: 10.1016/j.chom.2012.01.007. Epub 2012 Feb 1.

2.

Evolutionary toggling of Vpx/Vpr specificity results in divergent recognition of the restriction factor SAMHD1.

Fregoso OI, Ahn J, Wang C, Mehrens J, Skowronski J, Emerman M.

PLoS Pathog. 2013;9(7):e1003496. doi: 10.1371/journal.ppat.1003496. Epub 2013 Jul 18.

3.

The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx.

Lim ES, Fregoso OI, McCoy CO, Matsen FA, Malik HS, Emerman M.

Cell Host Microbe. 2012 Feb 16;11(2):194-204. doi: 10.1016/j.chom.2012.01.004. Epub 2012 Jan 26.

4.

Degradation of SAMHD1 by Vpx Is Independent of Uncoating.

Jáuregui P, Logue EC, Schultz ML, Fung S, Landau NR.

J Virol. 2015 May;89(10):5701-13. doi: 10.1128/JVI.03575-14. Epub 2015 Mar 11.

5.

HIV/simian immunodeficiency virus (SIV) accessory virulence factor Vpx loads the host cell restriction factor SAMHD1 onto the E3 ubiquitin ligase complex CRL4DCAF1.

Ahn J, Hao C, Yan J, DeLucia M, Mehrens J, Wang C, Gronenborn AM, Skowronski J.

J Biol Chem. 2012 Apr 6;287(15):12550-8. doi: 10.1074/jbc.M112.340711. Epub 2012 Feb 23.

6.

Variation of two primate lineage-specific residues in human SAMHD1 confers resistance to N terminus-targeted SIV Vpx proteins.

Wei W, Guo H, Gao Q, Markham R, Yu XF.

J Virol. 2014 Jan;88(1):583-91. doi: 10.1128/JVI.02866-13. Epub 2013 Oct 30.

7.

Structural Basis of Clade-specific Engagement of SAMHD1 (Sterile α Motif and Histidine/Aspartate-containing Protein 1) Restriction Factors by Lentiviral Viral Protein X (Vpx) Virulence Factors.

Wu Y, Koharudin LM, Mehrens J, DeLucia M, Byeon CH, Byeon IJ, Calero G, Ahn J, Gronenborn AM.

J Biol Chem. 2015 Jul 17;290(29):17935-45. doi: 10.1074/jbc.M115.665513. Epub 2015 Jun 4.

8.

HIV-2 and SIVmac accessory virulence factor Vpx down-regulates SAMHD1 enzyme catalysis prior to proteasome-dependent degradation.

DeLucia M, Mehrens J, Wu Y, Ahn J.

J Biol Chem. 2013 Jun 28;288(26):19116-26. doi: 10.1074/jbc.M113.469007. Epub 2013 May 15.

9.

Co-evolution of primate SAMHD1 and lentivirus Vpx leads to the loss of the vpx gene in HIV-1 ancestor.

Zhang C, de Silva S, Wang JH, Wu L.

PLoS One. 2012;7(5):e37477. doi: 10.1371/journal.pone.0037477. Epub 2012 May 4.

10.

The efficiency of Vpx-mediated SAMHD1 antagonism does not correlate with the potency of viral control in HIV-2-infected individuals.

Yu H, Usmani SM, Borch A, Krämer J, Stürzel CM, Khalid M, Li X, Krnavek D, van der Ende ME, Osterhaus AD, Gruters RA, Kirchhoff F.

Retrovirology. 2013 Mar 5;10:27. doi: 10.1186/1742-4690-10-27.

11.

Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac.

Brandariz-Nuñez A, Valle-Casuso JC, White TE, Laguette N, Benkirane M, Brojatsch J, Diaz-Griffero F.

Retrovirology. 2012 Jun 12;9:49. doi: 10.1186/1742-4690-9-49.

12.

A novel DCAF1-binding motif required for Vpx-mediated degradation of nuclear SAMHD1 and Vpr-induced G2 arrest.

Wei W, Guo H, Han X, Liu X, Zhou X, Zhang W, Yu XF.

Cell Microbiol. 2012 Nov;14(11):1745-56. doi: 10.1111/j.1462-5822.2012.01835.x. Epub 2012 Aug 9.

PMID:
22776683
13.

Functional analysis of the relationship between Vpx and the restriction factor SAMHD1.

Berger G, Turpin J, Cordeil S, Tartour K, Nguyen XN, Mahieux R, Cimarelli A.

J Biol Chem. 2012 Nov 30;287(49):41210-7. doi: 10.1074/jbc.M112.403816. Epub 2012 Oct 17.

14.

Nucleotide embargo by SAMHD1: a strategy to block retroviral infection.

Pauls E, Ballana E, Esté JA.

Antiviral Res. 2013 Feb;97(2):180-2. doi: 10.1016/j.antiviral.2012.12.009. Epub 2012 Dec 21.

PMID:
23266292
15.

Molecular determinants for recognition of divergent SAMHD1 proteins by the lentiviral accessory protein Vpx.

Schwefel D, Boucherit VC, Christodoulou E, Walker PA, Stoye JP, Bishop KN, Taylor IA.

Cell Host Microbe. 2015 Apr 8;17(4):489-99. doi: 10.1016/j.chom.2015.03.004.

16.

Mutational analysis of HIV-2 Vpx shows that proline residue 109 in the poly-proline motif regulates degradation of SAMHD1.

Ciftci HI, Fujino H, Koga R, Yamamoto M, Kawamura S, Tateishi H, Iwatani Y, Otsuka M, Fujita M.

FEBS Lett. 2015 Jun 4;589(13):1505-14. doi: 10.1016/j.febslet.2015.04.038. Epub 2015 Apr 30.

17.

Characterization of the interactions between SIVrcm Vpx and red-capped mangabey SAMHD1.

Li J, Xu F, Hu S, Zhou J, Mei S, Zhao X, Cen S, Jin Q, Liang C, Guo F.

Biochem J. 2015 Jun 1;468(2):303-13. doi: 10.1042/BJ20141331.

PMID:
25791246
18.

Lentivirus Vpr and Vpx accessory proteins usurp the cullin4-DDB1 (DCAF1) E3 ubiquitin ligase.

Romani B, Cohen EA.

Curr Opin Virol. 2012 Dec;2(6):755-63. doi: 10.1016/j.coviro.2012.09.010. Epub 2012 Oct 10. Review.

19.

Identification of critical regions in human SAMHD1 required for nuclear localization and Vpx-mediated degradation.

Guo H, Wei W, Wei Z, Liu X, Evans SL, Yang W, Wang H, Guo Y, Zhao K, Zhou JY, Yu XF.

PLoS One. 2013 Jul 11;8(7):e66201. doi: 10.1371/journal.pone.0066201. Print 2013.

20.

SAMHD1 specifically affects the antiviral potency of thymidine analog HIV reverse transcriptase inhibitors.

Ballana E, Badia R, Terradas G, Torres-Torronteras J, Ruiz A, Pauls E, Riveira-Muñoz E, Clotet B, Martí R, Esté JA.

Antimicrob Agents Chemother. 2014 Aug;58(8):4804-13. doi: 10.1128/AAC.03145-14. Epub 2014 Jun 9.

Supplemental Content

Support Center