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Items: 1 to 20 of 84

1.

Optimality in the development of intestinal crypts.

Itzkovitz S, Blat IC, Jacks T, Clevers H, van Oudenaarden A.

Cell. 2012 Feb 3;148(3):608-19. doi: 10.1016/j.cell.2011.12.025.

2.

Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells.

Snippert HJ, van der Flier LG, Sato T, van Es JH, van den Born M, Kroon-Veenboer C, Barker N, Klein AM, van Rheenen J, Simons BD, Clevers H.

Cell. 2010 Oct 1;143(1):134-44. doi: 10.1016/j.cell.2010.09.016.

3.

Expansion of intestinal epithelial stem cells during murine development.

Dehmer JJ, Garrison AP, Speck KE, Dekaney CM, Van Landeghem L, Sun X, Henning SJ, Helmrath MA.

PLoS One. 2011;6(11):e27070. doi: 10.1371/journal.pone.0027070. Epub 2011 Nov 10.

4.

A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable.

Tian H, Biehs B, Warming S, Leong KG, Rangell L, Klein OD, de Sauvage FJ.

Nature. 2011 Sep 18;478(7368):255-9. doi: 10.1038/nature10408. Erratum in: Nature. 2012 Feb 2;482(7383):120.

5.

Robust cre-mediated recombination in small intestinal stem cells utilizing the olfm4 locus.

Schuijers J, van der Flier LG, van Es J, Clevers H.

Stem Cell Reports. 2014 Aug 12;3(2):234-41. doi: 10.1016/j.stemcr.2014.05.018. Epub 2014 Jun 26.

6.

Effects of dose rates on radiation-induced replenishment of intestinal stem cells determined by Lgr5 lineage tracing.

Otsuka K, Iwasaki T.

J Radiat Res. 2015 Jul;56(4):615-22. doi: 10.1093/jrr/rrv012. Epub 2015 Apr 1.

7.

Very long-term self-renewal of small intestine, colon, and hair follicles from cycling Lgr5+ve stem cells.

Barker N, van Es JH, Jaks V, Kasper M, Snippert H, Toftgård R, Clevers H.

Cold Spring Harb Symp Quant Biol. 2008;73:351-6. doi: 10.1101/sqb.2008.72.003.

PMID:
19478326
8.

Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells.

Kim TH, Escudero S, Shivdasani RA.

Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3932-7. doi: 10.1073/pnas.1113890109. Epub 2012 Feb 21.

9.

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche.

Sato T, Vries RG, Snippert HJ, van de Wetering M, Barker N, Stange DE, van Es JH, Abo A, Kujala P, Peters PJ, Clevers H.

Nature. 2009 May 14;459(7244):262-5. doi: 10.1038/nature07935. Epub 2009 Mar 29.

PMID:
19329995
10.

Single-cell messenger RNA sequencing reveals rare intestinal cell types.

Grün D, Lyubimova A, Kester L, Wiebrands K, Basak O, Sasaki N, Clevers H, van Oudenaarden A.

Nature. 2015 Sep 10;525(7568):251-5. doi: 10.1038/nature14966. Epub 2015 Aug 19.

PMID:
26287467
11.

Identification of stem cells in small intestine and colon by marker gene Lgr5.

Barker N, van Es JH, Kuipers J, Kujala P, van den Born M, Cozijnsen M, Haegebarth A, Korving J, Begthel H, Peters PJ, Clevers H.

Nature. 2007 Oct 25;449(7165):1003-7. Epub 2007 Oct 14.

PMID:
17934449
12.

Single-molecule transcript counting of stem-cell markers in the mouse intestine.

Itzkovitz S, Lyubimova A, Blat IC, Maynard M, van Es J, Lees J, Jacks T, Clevers H, van Oudenaarden A.

Nat Cell Biol. 2011 Nov 27;14(1):106-14. doi: 10.1038/ncb2384.

13.

Enriched Intestinal Stem Cell Seeding Improves the Architecture of Tissue-Engineered Intestine.

Liu Y, Rager T, Johnson J, Enmark J, Besner GE.

Tissue Eng Part C Methods. 2015 Aug;21(8):816-24. doi: 10.1089/ten.TEC.2014.0389. Epub 2015 Mar 12.

PMID:
25603285
14.

Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters.

Tetteh PW, Basak O, Farin HF, Wiebrands K, Kretzschmar K, Begthel H, van den Born M, Korving J, de Sauvage F, van Es JH, van Oudenaarden A, Clevers H.

Cell Stem Cell. 2016 Feb 4;18(2):203-13. doi: 10.1016/j.stem.2016.01.001. Epub 2016 Jan 28.

15.

Small intestinal stem cell markers.

Montgomery RK, Breault DT.

J Anat. 2008 Jul;213(1):52-8. doi: 10.1111/j.1469-7580.2008.00925.x. Review.

16.

Frizzled7 functions as a Wnt receptor in intestinal epithelial Lgr5(+) stem cells.

Flanagan DJ, Phesse TJ, Barker N, Schwab RH, Amin N, Malaterre J, Stange DE, Nowell CJ, Currie SA, Saw JT, Beuchert E, Ramsay RG, Sansom OJ, Ernst M, Clevers H, Vincan E.

Stem Cell Reports. 2015 May 12;4(5):759-67. doi: 10.1016/j.stemcr.2015.03.003. Epub 2015 Apr 16.

17.

Primary mouse small intestinal epithelial cell cultures.

Sato T, Clevers H.

Methods Mol Biol. 2013;945:319-28. doi: 10.1007/978-1-62703-125-7_19.

PMID:
23097115
18.

The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers.

Muñoz J, Stange DE, Schepers AG, van de Wetering M, Koo BK, Itzkovitz S, Volckmann R, Kung KS, Koster J, Radulescu S, Myant K, Versteeg R, Sansom OJ, van Es JH, Barker N, van Oudenaarden A, Mohammed S, Heck AJ, Clevers H.

EMBO J. 2012 Jun 12;31(14):3079-91. doi: 10.1038/emboj.2012.166.

19.

Krüppel-like factor 5 is essential for proliferation and survival of mouse intestinal epithelial stem cells.

Nandan MO, Ghaleb AM, Bialkowska AB, Yang VW.

Stem Cell Res. 2015 Jan;14(1):10-9. doi: 10.1016/j.scr.2014.10.008. Epub 2014 Nov 6.

20.

Loss of caveolin-1 causes the hyper-proliferation of intestinal crypt stem cells, with increased sensitivity to whole body gamma-radiation.

Li J, Hassan GS, Williams TM, Minetti C, Pestell RG, Tanowitz HB, Frank PG, Sotgia F, Lisanti MP.

Cell Cycle. 2005 Dec;4(12):1817-25. Epub 2005 Dec 22.

PMID:
16294037

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