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Inhibition of Wnt/β-catenin signaling by a soluble collagen-derived frizzled domain interacting with Wnt3a and the receptors frizzled 1 and 8.

Hendaoui I, Lavergne E, Lee HS, Hong SH, Kim HZ, Parent C, Heuzé-Vourc'h N, Clément B, Musso O.

PLoS One. 2012;7(1):e30601. doi: 10.1371/journal.pone.0030601. Epub 2012 Jan 27. Erratum in: PLoS One. 2012;7(3). doi:10.1371/annotation/bd37b3ad-c242-4e77-9ef3-8e92d1f105f5.


A cryptic frizzled module in cell surface collagen 18 inhibits Wnt/beta-catenin signaling.

Quélard D, Lavergne E, Hendaoui I, Elamaa H, Tiirola U, Heljasvaara R, Pihlajaniemi T, Clément B, Musso O.

PLoS One. 2008 Apr 2;3(4):e1878. doi: 10.1371/journal.pone.0001878.


Blocking Wnt signaling by SFRP-like molecules inhibits in vivo cell proliferation and tumor growth in cells carrying active β-catenin.

Lavergne E, Hendaoui I, Coulouarn C, Ribault C, Leseur J, Eliat PA, Mebarki S, Corlu A, Clément B, Musso O.

Oncogene. 2011 Jan 27;30(4):423-33. doi: 10.1038/onc.2010.432. Epub 2010 Sep 20.


Secreted Frizzled-related protein potentiation versus inhibition of Wnt3a/β-catenin signaling.

Xavier CP, Melikova M, Chuman Y, Üren A, Baljinnyam B, Rubin JS.

Cell Signal. 2014 Jan;26(1):94-101. doi: 10.1016/j.cellsig.2013.09.016. Epub 2013 Sep 28.


Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6.

Bourhis E, Tam C, Franke Y, Bazan JF, Ernst J, Hwang J, Costa M, Cochran AG, Hannoush RN.

J Biol Chem. 2010 Mar 19;285(12):9172-9. doi: 10.1074/jbc.M109.092130. Epub 2010 Jan 21.


Wnt-4 activates the canonical beta-catenin-mediated Wnt pathway and binds Frizzled-6 CRD: functional implications of Wnt/beta-catenin activity in kidney epithelial cells.

Lyons JP, Mueller UW, Ji H, Everett C, Fang X, Hsieh JC, Barth AM, McCrea PD.

Exp Cell Res. 2004 Aug 15;298(2):369-87.


Murine Frizzled-1 behaves as an antagonist of the canonical Wnt/beta-catenin signaling.

Roman-Roman S, Shi DL, Stiot V, Haÿ E, Vayssière B, Garcia T, Baron R, Rawadi G.

J Biol Chem. 2004 Feb 13;279(7):5725-33. Epub 2003 Nov 24.


Soluble Frizzled-7 receptor inhibits Wnt signaling and sensitizes hepatocellular carcinoma cells towards doxorubicin.

Wei W, Chua MS, Grepper S, So SK.

Mol Cancer. 2011 Feb 11;10:16. doi: 10.1186/1476-4598-10-16.


Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains.

Dann CE, Hsieh JC, Rattner A, Sharma D, Nathans J, Leahy DJ.

Nature. 2001 Jul 5;412(6842):86-90.


Stably overexpressed human Frizzled-2 signals through the beta-catenin pathway and does not activate Ca2+-mobilization in Human Embryonic Kidney 293 cells.

Verkaar F, van Rosmalen JW, Smits JF, Blankesteijn WM, Zaman GJ.

Cell Signal. 2009 Jan;21(1):22-33. doi: 10.1016/j.cellsig.2008.09.008. Epub 2008 Sep 25.


Frizzled-1 is involved in the neuroprotective effect of Wnt3a against Abeta oligomers.

Chacón MA, Varela-Nallar L, Inestrosa NC.

J Cell Physiol. 2008 Oct;217(1):215-27. doi: 10.1002/jcp.21497.


Binding of sFRP-3 to EGF in the extra-cellular space affects proliferation, differentiation and morphogenetic events regulated by the two molecules.

Scardigli R, Gargioli C, Tosoni D, Borello U, Sampaolesi M, Sciorati C, Cannata S, Clementi E, Brunelli S, Cossu G.

PLoS One. 2008 Jun 18;3(6):e2471. doi: 10.1371/journal.pone.0002471.


Effects of secreted frizzled-related protein 3 on osteoblasts in vitro.

Chung YS, Baylink DJ, Srivastava AK, Amaar Y, Tapia B, Kasukawa Y, Mohan S.

J Bone Miner Res. 2004 Sep;19(9):1395-402. Epub 2004 May 3.


Activation of the canonical wingless/T-cell factor signaling pathway promotes invasive differentiation of human trophoblast.

Pollheimer J, Loregger T, Sonderegger S, Saleh L, Bauer S, Bilban M, Czerwenka K, Husslein P, Knöfler M.

Am J Pathol. 2006 Apr;168(4):1134-47.


Wnt3-frizzled 1 chimera as a model to study canonical Wnt signaling.

Bhat RA, Stauffer B, Della Pietra A, Bodine PV.

J Cell Biochem. 2010 Apr 1;109(5):876-84. doi: 10.1002/jcb.22447.


Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function.

Varela-Nallar L, Grabowski CP, Alfaro IE, Alvarez AR, Inestrosa NC.

Neural Dev. 2009 Nov 2;4:41. doi: 10.1186/1749-8104-4-41.

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