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Items: 1 to 20 of 92

1.

Whole genome sequences of a male and female supercentenarian, ages greater than 114 years.

Sebastiani P, Riva A, Montano M, Pham P, Torkamani A, Scherba E, Benson G, Milton JN, Baldwin CT, Andersen S, Schork NJ, Steinberg MH, Perls TT.

Front Genet. 2012 Jan 3;2:90. doi: 10.3389/fgene.2011.00090. eCollection 2011.

2.

Whole-genome sequencing of the world's oldest people.

Gierman HJ, Fortney K, Roach JC, Coles NS, Li H, Glusman G, Markov GJ, Smith JD, Hood L, Coles LS, Kim SK.

PLoS One. 2014 Nov 12;9(11):e112430. doi: 10.1371/journal.pone.0112430. eCollection 2014.

3.

Genetic Investigation of an Iranian Supercentenarian by Whole Exome Sequencing.

Akhtarkhavari T, Joghataei MT, Fattahi Z, Akbari MR, Larti F, Najmabadi H, Kahrizi K.

Arch Iran Med. 2015 Oct;18(10):688-97. doi: 0151810/AIM.009.

4.

Genetics of healthy aging and longevity.

Brooks-Wilson AR.

Hum Genet. 2013 Dec;132(12):1323-38. doi: 10.1007/s00439-013-1342-z. Epub 2013 Aug 8. Review.

5.

Whole genome sequences of 2 octogenarians with sustained cognitive abilities.

Nickles D, Madireddy L, Patel N, Isobe N, Miller BL, Baranzini SE, Kramer JH, Oksenberg JR.

Neurobiol Aging. 2015 Mar;36(3):1435-8. doi: 10.1016/j.neurobiolaging.2014.11.003. Epub 2014 Dec 16.

6.

Demographic, phenotypic, and genetic characteristics of centenarians in Okinawa and Honshu, Japan: Part 2 Honshu, Japan.

Arai Y, Sasaki T, Hirose N.

Mech Ageing Dev. 2017 Feb 16. pii: S0047-6374(16)30235-4. doi: 10.1016/j.mad.2017.02.005. [Epub ahead of print] Review.

PMID:
28214534
7.

Burden of Common Complex Disease Variants in the Exomes of Two Healthy Centenarian Brothers.

Tindale LC, Zeng A, Bretherick KL, Leach S, Thiessen N, Brooks-Wilson AR.

Gerontology. 2015;62(1):58-62. doi: 10.1159/000430462. Epub 2015 Jun 10.

PMID:
26066993
8.

Genetic variation and human longevity.

Soerensen M.

Dan Med J. 2012 May;59(5):B4454.

PMID:
22549493
9.

Four Genome-Wide Association Studies Identify New Extreme Longevity Variants.

Sebastiani P, Gurinovich A, Bae H, Andersen S, Malovini A, Atzmon G, Villa F, Kraja AT, Ben-Avraham D, Barzilai N, Puca A, Perls TT.

J Gerontol A Biol Sci Med Sci. 2017 Mar 15. doi: 10.1093/gerona/glx027. [Epub ahead of print]

PMID:
28329165
10.

Whole-Genome Sequencing of a Healthy Aging Cohort.

Erikson GA, Bodian DL, Rueda M, Molparia B, Scott ER, Scott-Van Zeeland AA, Topol SE, Wineinger NE, Niederhuber JE, Topol EJ, Torkamani A.

Cell. 2016 May 5;165(4):1002-11. doi: 10.1016/j.cell.2016.03.022. Epub 2016 Apr 21.

11.

Models to explore genetics of human aging.

Karasik D, Newman A.

Adv Exp Med Biol. 2015;847:141-61. doi: 10.1007/978-1-4939-2404-2_7. Review.

PMID:
25916590
12.

Exome and whole genome sequencing in aging and longevity.

van den Akker EB, Deelen J, Slagboom PE, Beekman M.

Adv Exp Med Biol. 2015;847:127-39. doi: 10.1007/978-1-4939-2404-2_6. Review.

PMID:
25916589
13.

The genetics of aging.

Perls T, Kunkel L, Puca A.

Curr Opin Genet Dev. 2002 Jun;12(3):362-9. Review.

PMID:
12076681
14.

Discovery of novel non-synonymous SNP variants in 988 candidate genes from 6 centenarians by target capture and next-generation sequencing.

Han J, Ryu S, Moskowitz DM, Rothenberg D, Leahy DJ, Atzmon G, Barzilai N, Suh Y.

Mech Ageing Dev. 2013 Oct;134(10):478-85. doi: 10.1016/j.mad.2013.01.005. Epub 2013 Feb 1.

15.

Neuropathology of supercentenarians - four autopsy case studies.

Takao M, Hirose N, Arai Y, Mihara B, Mimura M.

Acta Neuropathol Commun. 2016 Sep 2;4(1):97. doi: 10.1186/s40478-016-0368-6.

16.

Variations of the angiotensin II type 1 receptor gene are associated with extreme human longevity.

Benigni A, Orisio S, Noris M, Iatropoulos P, Castaldi D, Kamide K, Rakugi H, Arai Y, Todeschini M, Ogliari G, Imai E, Gondo Y, Hirose N, Mari D, Remuzzi G.

Age (Dordr). 2013 Jun;35(3):993-1005. doi: 10.1007/s11357-012-9408-8. Epub 2012 May 9.

17.

Genetics of aging, health, and survival: dynamic regulation of human longevity related traits.

Yashin AI, Wu D, Arbeeva LS, Arbeev KG, Kulminski AM, Akushevich I, Kovtun M, Culminskaya I, Stallard E, Li M, Ukraintseva SV.

Front Genet. 2015 Apr 13;6:122. doi: 10.3389/fgene.2015.00122. eCollection 2015.

18.

Buffering mechanisms in aging: a systems approach toward uncovering the genetic component of aging.

Bergman A, Atzmon G, Ye K, MacCarthy T, Barzilai N.

PLoS Comput Biol. 2007 Aug;3(8):e170. Epub 2007 Jul 18.

19.

Meta‐analysis of genetic variants associated with human exceptional longevity.

Sebastiani P, Bae H, Sun FX, Andersen SL, Daw EW, Malovini A, Kojima T, Hirose N, Schupf N, Puca A, Perls TT.

Aging (Albany NY). 2013 Sep;5(9):653-61.

20.

Genetic determinants of exceptional human longevity: insights from the Okinawa Centenarian Study.

Willcox DC, Willcox BJ, Hsueh WC, Suzuki M.

Age (Dordr). 2006 Dec;28(4):313-32. doi: 10.1007/s11357-006-9020-x. Epub 2006 Dec 8.

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