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TORC2 signaling is antagonized by protein phosphatase 2A and the Far complex in Saccharomyces cerevisiae.

Pracheil T, Thornton J, Liu Z.

Genetics. 2012 Apr;190(4):1325-39. doi: 10.1534/genetics.111.138305.


Tiered assembly of the yeast Far3-7-8-9-10-11 complex at the endoplasmic reticulum.

Pracheil T, Liu Z.

J Biol Chem. 2013 Jun 7;288(23):16986-97. doi: 10.1074/jbc.M113.451674.


Molecular organization of target of rapamycin complex 2.

Wullschleger S, Loewith R, Oppliger W, Hall MN.

J Biol Chem. 2005 Sep 2;280(35):30697-704.


Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control.

Loewith R, Jacinto E, Wullschleger S, Lorberg A, Crespo JL, Bonenfant D, Oppliger W, Jenoe P, Hall MN.

Mol Cell. 2002 Sep;10(3):457-68.


Rapamycin inhibits yeast nucleotide excision repair independently of tor kinases.

Limson MV, Sweder KS.

Toxicol Sci. 2010 Jan;113(1):77-84. doi: 10.1093/toxsci/kfp238.


Involvement of Saccharomyces cerevisiae Avo3p/Tsc11p in maintaining TOR complex 2 integrity and coupling to downstream signaling.

Ho HL, Lee HY, Liao HC, Chen MY.

Eukaryot Cell. 2008 Aug;7(8):1328-43. doi: 10.1128/EC.00065-08.


Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization.

Kamada Y, Fujioka Y, Suzuki NN, Inagaki F, Wullschleger S, Loewith R, Hall MN, Ohsumi Y.

Mol Cell Biol. 2005 Aug;25(16):7239-48.


Insight into Tor2, a budding yeast microdomain protein.

Bartlett K, Kim K.

Eur J Cell Biol. 2014 Mar;93(3):87-97. doi: 10.1016/j.ejcb.2014.01.004. Review.


PP2A phosphatase activity is required for stress and Tor kinase regulation of yeast stress response factor Msn2p.

Santhanam A, Hartley A, Düvel K, Broach JR, Garrett S.

Eukaryot Cell. 2004 Oct;3(5):1261-71.


Selective ATP-competitive inhibitors of TOR suppress rapamycin-insensitive function of TORC2 in Saccharomyces cerevisiae.

Liu Q, Ren T, Fresques T, Oppliger W, Niles BJ, Hur W, Sabatini DM, Hall MN, Powers T, Gray NS.

ACS Chem Biol. 2012 Jun 15;7(6):982-7. doi: 10.1021/cb300058v.


Intranuclear function for protein phosphatase 2A: Pph21 and Pph22 are required for rapamycin-induced GATA factor binding to the DAL5 promoter in yeast.

Georis I, Tate JJ, Feller A, Cooper TG, Dubois E.

Mol Cell Biol. 2011 Jan;31(1):92-104. doi: 10.1128/MCB.00482-10.


Molecular Basis of the Rapamycin Insensitivity of Target Of Rapamycin Complex 2.

Gaubitz C, Oliveira TM, Prouteau M, Leitner A, Karuppasamy M, Konstantinidou G, Rispal D, Eltschinger S, Robinson GC, Thore S, Aebersold R, Schaffitzel C, Loewith R.

Mol Cell. 2015 Jun 18;58(6):977-88. doi: 10.1016/j.molcel.2015.04.031.


The Saccharomyces cerevisiae homologue YPA1 of the mammalian phosphotyrosyl phosphatase activator of protein phosphatase 2A controls progression through the G1 phase of the yeast cell cycle.

Van Hoof C, Janssens V, De Baere I, de Winde JH, Winderickx J, Dumortier F, Thevelein JM, Merlevede W, Goris J.

J Mol Biol. 2000 Sep 8;302(1):103-20.


Suppressors of ipl1-2 in components of a Glc7 phosphatase complex, Cdc48 AAA ATPase, TORC1, and the kinetochore.

Robinson LC, Phillips J, Brou L, Boswell EP, Tatchell K.

G3 (Bethesda). 2012 Dec;2(12):1687-701. doi: 10.1534/g3.112.003814.


The TEA transcription factor Tec1 links TOR and MAPK pathways to coordinate yeast development.

Brückner S, Kern S, Birke R, Saugar I, Ulrich HD, Mösch HU.

Genetics. 2011 Oct;189(2):479-94. doi: 10.1534/genetics.111.133629.


Chemical genetics of rapamycin-insensitive TORC2 in S. cerevisiae.

Kliegman JI, Fiedler D, Ryan CJ, Xu YF, Su XY, Thomas D, Caccese MC, Cheng A, Shales M, Rabinowitz JD, Krogan NJ, Shokat KM.

Cell Rep. 2013 Dec 26;5(6):1725-36. doi: 10.1016/j.celrep.2013.11.040.

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