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AT2 receptor non-peptide agonist C21 promotes natriuresis in obese Zucker rats.

Ali Q, Hussain T.

Hypertens Res. 2012 Jun;35(6):654-60. doi: 10.1038/hr.2012.13. Epub 2012 Feb 2.


Angiotensin II Type 2 Receptor and Receptor Mas Are Colocalized and Functionally Interdependent in Obese Zucker Rat Kidney.

Patel SN, Ali Q, Samuel P, Steckelings UM, Hussain T.

Hypertension. 2017 Oct;70(4):831-838. doi: 10.1161/HYPERTENSIONAHA.117.09679. Epub 2017 Aug 21.


Inhibition of NAD(P)H oxidase potentiates AT2 receptor agonist-induced natriuresis in Sprague-Dawley rats.

Sabuhi R, Asghar M, Hussain T.

Am J Physiol Renal Physiol. 2010 Oct;299(4):F815-20. doi: 10.1152/ajprenal.00310.2010. Epub 2010 Jul 28.


ATâ‚‚ receptor activation induces natriuresis and lowers blood pressure.

Kemp BA, Howell NL, Gildea JJ, Keller SR, Padia SH, Carey RM.

Circ Res. 2014 Jul 18;115(3):388-99. doi: 10.1161/CIRCRESAHA.115.304110. Epub 2014 Jun 5.


Diminished natriuretic response to dopamine D1 receptor agonist, SKF-38393 in obese Zucker rats.

Marwaha A, Lokhandwala MF.

Clin Exp Hypertens. 2003 Nov;25(8):509-15.


Intrarenal aminopeptidase N inhibition restores defective angiontesin II type 2-mediated natriuresis in spontaneously hypertensive rats.

Padia SH, Howell NL, Kemp BA, Fournie-Zaluski MC, Roques BP, Carey RM.

Hypertension. 2010 Feb;55(2):474-80. doi: 10.1161/HYPERTENSIONAHA.109.144956. Epub 2009 Dec 7.


Angiotensin AT2 receptor agonist prevents salt-sensitive hypertension in obese Zucker rats.

Ali Q, Patel S, Hussain T.

Am J Physiol Renal Physiol. 2015 Jun 15;308(12):F1379-85. doi: 10.1152/ajprenal.00002.2015. Epub 2015 Apr 8.


Renal angiotensin II AT2 receptors promote natriuresis in streptozotocin-induced diabetic rats.

Hakam AC, Siddiqui AH, Hussain T.

Am J Physiol Renal Physiol. 2006 Feb;290(2):F503-8. Epub 2005 Oct 4.


The subtype 2 of angiotensin II receptors and pressure-natriuresis in adult rat kidneys.

Liu KL, Lo M, Grouzmann E, Mutter M, Sassard J.

Br J Pharmacol. 1999 Feb;126(3):826-32.


Renal angiotensin type 2 receptors mediate natriuresis via angiotensin III in the angiotensin II type 1 receptor-blocked rat.

Padia SH, Howell NL, Siragy HM, Carey RM.

Hypertension. 2006 Mar;47(3):537-44. Epub 2005 Dec 27.


Intrarenal angiotensin III infusion induces natriuresis and angiotensin type 2 receptor translocation in Wistar-Kyoto but not in spontaneously hypertensive rats.

Padia SH, Kemp BA, Howell NL, Gildea JJ, Keller SR, Carey RM.

Hypertension. 2009 Feb;53(2):338-43. doi: 10.1161/HYPERTENSIONAHA.108.124198. Epub 2008 Dec 15.


Angiotensin II AT2 receptors inhibit proximal tubular Na+-K+-ATPase activity via a NO/cGMP-dependent pathway.

Hakam AC, Hussain T.

Am J Physiol Renal Physiol. 2006 Jun;290(6):F1430-6. Epub 2005 Dec 27.


Intrarenal angiotensin III is the predominant agonist for proximal tubule angiotensin type 2 receptors.

Kemp BA, Bell JF, Rottkamp DM, Howell NL, Shao W, Navar LG, Padia SH, Carey RM.

Hypertension. 2012 Aug;60(2):387-95. doi: 10.1161/HYPERTENSIONAHA.112.191403. Epub 2012 Jun 11.


Angiotensin II Type 2-Receptor Agonist C21 Reduces Proteinuria and Oxidative Stress in Kidney of High-Salt-Fed Obese Zucker Rats.

Patel SN, Ali Q, Hussain T.

Hypertension. 2016 May;67(5):906-15. doi: 10.1161/HYPERTENSIONAHA.115.06881. Epub 2016 Mar 28.


Chronic candesartan alters expression and activity of NKCC2, NCC, and ENaC in the obese Zucker rat.

Madala Halagappa VK, Tiwari S, Riazi S, Hu X, Ecelbarger CM.

Am J Physiol Renal Physiol. 2008 May;294(5):F1222-31. doi: 10.1152/ajprenal.00604.2007. Epub 2008 Feb 27.


Endothelin induces diuresis and natriuresis in the rat by acting on proximal tubular cells through a mechanism mediated by lipoxygenase products.

Perico N, Cornejo RP, Benigni A, Malanchini B, Ladny JR, Remuzzi G.

J Am Soc Nephrol. 1991 Jul;2(1):57-69.


AT2 Receptor Activation Prevents Sodium Retention and Reduces Blood Pressure in Angiotensin II-Dependent Hypertension.

Kemp BA, Howell NL, Keller SR, Gildea JJ, Padia SH, Carey RM.

Circ Res. 2016 Aug 5;119(4):532-43. doi: 10.1161/CIRCRESAHA.116.308384. Epub 2016 Jun 20.


Aldosterone infusion with high-NaCl diet increases blood pressure in obese but not lean Zucker rats.

Riazi S, Khan O, Hu X, Ecelbarger CA.

Am J Physiol Renal Physiol. 2006 Sep;291(3):F597-605. Epub 2006 Apr 4.

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