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Items: 1 to 20 of 116

1.

The unmet need in the elderly: how immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccines.

McElhaney JE, Zhou X, Talbot HK, Soethout E, Bleackley RC, Granville DJ, Pawelec G.

Vaccine. 2012 Mar 9;30(12):2060-7. doi: 10.1016/j.vaccine.2012.01.015. Epub 2012 Jan 27. Review.

2.

Cytomegalovirus Seropositivity Predicts a Decline in the T Cell But Not the Antibody Response to Influenza in Vaccinated Older Adults Independent of Type 2 Diabetes Status.

Haq K, Fulop T, Tedder G, Gentleman B, Garneau H, Meneilly GS, Kleppinger A, Pawelec G, McElhaney JE.

J Gerontol A Biol Sci Med Sci. 2017 Sep 1;72(9):1163-1170. doi: 10.1093/gerona/glw216.

PMID:
27789617
3.

The unmet need in the elderly: designing new influenza vaccines for older adults.

McElhaney JE.

Vaccine. 2005 Jul 8;23 Suppl 1:S10-25.

PMID:
15908062
4.

Immunosenescence: Implications for response to infection and vaccination in older people.

Pera A, Campos C, López N, Hassouneh F, Alonso C, Tarazona R, Solana R.

Maturitas. 2015 Sep;82(1):50-5. doi: 10.1016/j.maturitas.2015.05.004. Epub 2015 May 18. Review.

PMID:
26044074
5.

Latent infection with cytomegalovirus is associated with poor memory CD4 responses to influenza A core proteins in the elderly.

Derhovanessian E, Maier AB, Hähnel K, McElhaney JE, Slagboom EP, Pawelec G.

J Immunol. 2014 Oct 1;193(7):3624-31. doi: 10.4049/jimmunol.1303361. Epub 2014 Sep 3.

6.

Immunosenescence: role and measurement in influenza vaccine response among the elderly.

Targonski PV, Jacobson RM, Poland GA.

Vaccine. 2007 Apr 20;25(16):3066-9. Epub 2007 Jan 16. Review.

PMID:
17275144
7.

Cytomegalovirus infection and responsiveness to influenza vaccination in elderly residents of long-term care facilities.

den Elzen WP, Vossen AC, Cools HJ, Westendorp RG, Kroes AC, Gussekloo J.

Vaccine. 2011 Jun 24;29(29-30):4869-74. doi: 10.1016/j.vaccine.2011.03.086. Epub 2011 Apr 15.

PMID:
21497631
8.

[The role of anti-influenza vaccination in elderly persons].

Myśliwska J.

Przegl Epidemiol. 2002;56 Suppl 1:91-9. Review. Polish.

PMID:
12194236
9.

Low expression of activation marker CD69 and chemokine receptors CCR5 and CXCR3 on memory T cells after 2009 H1N1 influenza A antigen stimulation in vitro following H1N1 vaccination of HIV-infected individuals.

Chawansuntati K, Chotirosniramit N, Sugandhavesa P, Aurpibul L, Thetket S, Kosashunhanan N, Supindham T, Kaewthip O, Sroysuwan P, Sirisanthana T, Suparatpinyo K, Wipasa J.

Hum Vaccin Immunother. 2015;11(9):2253-65. doi: 10.1080/21645515.2015.1051275. Epub 2015 Jun 19.

10.

Impaired antibody response to influenza vaccine in HIV-infected and uninfected aging women is associated with immune activation and inflammation.

Parmigiani A, Alcaide ML, Freguja R, Pallikkuth S, Frasca D, Fischl MA, Pahwa S.

PLoS One. 2013 Nov 13;8(11):e79816. doi: 10.1371/journal.pone.0079816. eCollection 2013.

11.

Cytomegalovirus-associated accumulation of late-differentiated CD4 T-cells correlates with poor humoral response to influenza vaccination.

Derhovanessian E, Theeten H, Hähnel K, Van Damme P, Cools N, Pawelec G.

Vaccine. 2013 Jan 11;31(4):685-90. doi: 10.1016/j.vaccine.2012.11.041. Epub 2012 Nov 26.

PMID:
23196209
12.

Induction of alphadelta- and alphabeta-mediated T cell responses in healthy elderly subjects after influenza vaccination.

Re F, Donnini A, Provinciali M.

Biogerontology. 2006 Aug;7(4):249-59. Epub 2006 Jul 5.

PMID:
16821115
13.

Association between cytomegalovirus infection, enhanced proinflammatory response and low level of anti-hemagglutinins during the anti-influenza vaccination--an impact of immunosenescence.

Trzonkowski P, Myśliwska J, Szmit E, Wieckiewicz J, Lukaszuk K, Brydak LB, Machała M, Myśliwski A.

Vaccine. 2003 Sep 8;21(25-26):3826-36.

PMID:
12922116
14.

Aging and impaired immunity to influenza viruses: implications for vaccine development.

Liu WM, van der Zeijst BA, Boog CJ, Soethout EC.

Hum Vaccin. 2011 Jan-Feb;7 Suppl:94-8. Epub 2011 Jan 1. Review.

PMID:
21301210
15.

HIV infection Worsens Age-Associated Defects in Antibody Responses to Influenza Vaccine.

George VK, Pallikkuth S, Parmigiani A, Alcaide M, Fischl M, Arheart KL, Pahwa S.

J Infect Dis. 2015 Jun 15;211(12):1959-68. doi: 10.1093/infdis/jiu840. Epub 2015 Jan 2.

16.

Immunologic correlates of protection and potential role for adjuvants to improve influenza vaccines in older adults.

McElhaney JE, Coler RN, Baldwin SL.

Expert Rev Vaccines. 2013 Jul;12(7):759-66. doi: 10.1586/14760584.2013.811193. Review.

PMID:
23885821
17.

T cell responses are better correlates of vaccine protection in the elderly.

McElhaney JE, Xie D, Hager WD, Barry MB, Wang Y, Kleppinger A, Ewen C, Kane KP, Bleackley RC.

J Immunol. 2006 May 15;176(10):6333-9.

18.

Influenza vaccine-mediated protection in older adults: Impact of influenza infection, cytomegalovirus serostatus and vaccine dosage.

Merani S, Kuchel GA, Kleppinger A, McElhaney JE.

Exp Gerontol. 2017 Sep 27. pii: S0531-5565(17)30456-4. doi: 10.1016/j.exger.2017.09.015. [Epub ahead of print]

PMID:
28958701
19.

Improving immunogenicity and effectiveness of influenza vaccine in older adults.

Cao W, Kim JH, Chirkova T, Reber AJ, Biber R, Shay DK, Sambhara S.

Expert Rev Vaccines. 2011 Nov;10(11):1529-37. doi: 10.1586/erv.11.137. Review.

PMID:
22043953

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