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Items: 1 to 20 of 124

1.

UHRF1 coordinates peroxisome proliferator activated receptor gamma (PPARG) epigenetic silencing and mediates colorectal cancer progression.

Sabatino L, Fucci A, Pancione M, Carafa V, Nebbioso A, Pistore C, Babbio F, Votino C, Laudanna C, Ceccarelli M, Altucci L, Bonapace IM, Colantuoni V.

Oncogene. 2012 Dec 6;31(49):5061-72. doi: 10.1038/onc.2012.3. Epub 2012 Jan 30.

PMID:
22286757
2.

Epigenetic silencing of peroxisome proliferator-activated receptor γ is a biomarker for colorectal cancer progression and adverse patients' outcome.

Pancione M, Sabatino L, Fucci A, Carafa V, Nebbioso A, Forte N, Febbraro A, Parente D, Ambrosino C, Normanno N, Altucci L, Colantuoni V.

PLoS One. 2010 Dec 3;5(12):e14229. doi: 10.1371/journal.pone.0014229. Erratum in: PLoS One. 2011;6(1). doi: 10.1371/annotation/07419a37-33f1-4e4a-adc9-b186f305bae5.

3.

UHRF1 promotes proliferation of gastric cancer via mediating tumor suppressor gene hypermethylation.

Zhou L, Shang Y, Jin Z, Zhang W, Lv C, Zhao X, Liu Y, Li N, Liang J.

Cancer Biol Ther. 2015;16(8):1241-51. doi: 10.1080/15384047.2015.1056411. Epub 2015 Jul 6.

4.

The SRA protein UHRF1 promotes epigenetic crosstalks and is involved in prostate cancer progression.

Babbio F, Pistore C, Curti L, Castiglioni I, Kunderfranco P, Brino L, Oudet P, Seiler R, Thalman GN, Roggero E, Sarti M, Pinton S, Mello-Grand M, Chiorino G, Catapano CV, Carbone GM, Bonapace IM.

Oncogene. 2012 Nov 15;31(46):4878-87. doi: 10.1038/onc.2011.641. Epub 2012 Feb 13.

PMID:
22330138
5.

Epigenetic repression of regulator of G-protein signaling 2 by ubiquitin-like with PHD and ring-finger domain 1 promotes bladder cancer progression.

Ying L, Lin J, Qiu F, Cao M, Chen H, Liu Z, Huang Y.

FEBS J. 2015 Jan;282(1):174-82. doi: 10.1111/febs.13116. Epub 2014 Dec 3.

6.

UHRF1 promotes cell growth and metastasis through repression of p16(ink⁴a) in colorectal cancer.

Wang F, Yang YZ, Shi CZ, Zhang P, Moyer MP, Zhang HZ, Zou Y, Qin HL.

Ann Surg Oncol. 2012 Aug;19(8):2753-62. doi: 10.1245/s10434-011-2194-1. Epub 2012 Jan 5.

PMID:
22219067
7.

UHRF1 expression is upregulated and associated with cellular proliferation in colorectal cancer.

Kofunato Y, Kumamoto K, Saitou K, Hayase S, Okayama H, Miyamoto K, Sato Y, Katakura K, Nakamura I, Ohki S, Koyama Y, Unoki M, Takenoshita S.

Oncol Rep. 2012 Dec;28(6):1997-2002. doi: 10.3892/or.2012.2064. Epub 2012 Sep 27.

PMID:
23023523
8.

UHRF1 is associated with epigenetic silencing of BRCA1 in sporadic breast cancer.

Jin W, Chen L, Chen Y, Xu SG, Di GH, Yin WJ, Wu J, Shao ZM.

Breast Cancer Res Treat. 2010 Sep;123(2):359-73. doi: 10.1007/s10549-009-0652-2. Epub 2009 Nov 27.

PMID:
19943104
9.

Epigenetic silencing of HOPX promotes cancer progression in colorectal cancer.

Katoh H, Yamashita K, Waraya M, Margalit O, Ooki A, Tamaki H, Sakagami H, Kokubo K, Sidransky D, Watanabe M.

Neoplasia. 2012 Jul;14(7):559-71.

10.

Upregulated UHRF1 promotes bladder cancer cell invasion by epigenetic silencing of KiSS1.

Zhang Y, Huang Z, Zhu Z, Zheng X, Liu J, Han Z, Ma X, Zhang Y.

PLoS One. 2014 Oct 1;9(10):e104252. doi: 10.1371/journal.pone.0104252. eCollection 2014.

11.

Regulation of UHRF1 by microRNA-9 modulates colorectal cancer cell proliferation and apoptosis.

Zhu M, Xu Y, Ge M, Gui Z, Yan F.

Cancer Sci. 2015 Jul;106(7):833-9. doi: 10.1111/cas.12689. Epub 2015 Jun 17.

12.

Epigenetic changes in colorectal cancer.

Kondo Y, Issa JP.

Cancer Metastasis Rev. 2004 Jan-Jun;23(1-2):29-39. Review.

PMID:
15000147
13.

Colorectal cancer expression of peroxisome proliferator-activated receptor gamma (PPARG, PPARgamma) is associated with good prognosis.

Ogino S, Shima K, Baba Y, Nosho K, Irahara N, Kure S, Chen L, Toyoda S, Kirkner GJ, Wang YL, Giovannucci EL, Fuchs CS.

Gastroenterology. 2009 Apr;136(4):1242-50. doi: 10.1053/j.gastro.2008.12.048. Epub 2008 Dec 24.

14.

Regulation of UHRF1 by miR-146a/b modulates gastric cancer invasion and metastasis.

Zhou L, Zhao X, Han Y, Lu Y, Shang Y, Liu C, Li T, Jin Z, Fan D, Wu K.

FASEB J. 2013 Dec;27(12):4929-39. doi: 10.1096/fj.13-233387. Epub 2013 Aug 27.

15.

Negative modulation of the epigenetic regulator, UHRF1, by thyroid hormone receptors suppresses liver cancer cell growth.

Wu SM, Cheng WL, Liao CJ, Chi HC, Lin YH, Tseng YH, Tsai CY, Chen CY, Lin SL, Chen WJ, Yeh YH, Huang CY, Chen MH, Yeh YC, Lin KH.

Int J Cancer. 2015 Jul 1;137(1):37-49. doi: 10.1002/ijc.29368. Epub 2014 Dec 10.

16.

Reduced beta-catenin and peroxisome proliferator-activated receptor-gamma expression levels are associated with colorectal cancer metastatic progression: correlation with tumor-associated macrophages, cyclooxygenase 2, and patient outcome.

Pancione M, Forte N, Sabatino L, Tomaselli E, Parente D, Febbraro A, Colantuoni V.

Hum Pathol. 2009 May;40(5):714-25. doi: 10.1016/j.humpath.2008.08.019. Epub 2009 Jan 3.

PMID:
19121846
17.

Drug discovery targeting epigenetic codes: the great potential of UHRF1, which links DNA methylation and histone modifications, as a drug target in cancers and toxoplasmosis.

Unoki M, Brunet J, Mousli M.

Biochem Pharmacol. 2009 Nov 15;78(10):1279-88. doi: 10.1016/j.bcp.2009.05.035. Epub 2009 Jun 6. Review.

PMID:
19501055
18.

CD47 activation-induced UHRF1 over-expression is associated with silencing of tumor suppressor gene p16INK4A in glioblastoma cells.

Boukhari A, Alhosin M, Bronner C, Sagini K, Truchot C, Sick E, Schini-Kerth VB, André P, Mély Y, Mousli M, Gies JP.

Anticancer Res. 2015 Jan;35(1):149-57.

PMID:
25550546
19.

Epigenetic inactivation of T-box transcription factor 5, a novel tumor suppressor gene, is associated with colon cancer.

Yu J, Ma X, Cheung KF, Li X, Tian L, Wang S, Wu CW, Wu WK, He M, Wang M, Ng SS, Sung JJ.

Oncogene. 2010 Dec 9;29(49):6464-74. doi: 10.1038/onc.2010.370. Epub 2010 Aug 30.

PMID:
20802524
20.

The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer.

Akino K, Toyota M, Suzuki H, Mita H, Sasaki Y, Ohe-Toyota M, Issa JP, Hinoda Y, Imai K, Tokino T.

Gastroenterology. 2005 Jul;129(1):156-69.

PMID:
16012945

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