Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 88

1.

Notch activation by the metalloproteinase ADAM17 regulates myeloproliferation and atopic barrier immunity by suppressing epithelial cytokine synthesis.

Murthy A, Shao YW, Narala SR, Molyneux SD, Zúñiga-Pflücker JC, Khokha R.

Immunity. 2012 Jan 27;36(1):105-19. doi: 10.1016/j.immuni.2012.01.005.

2.

The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling.

Weber S, Niessen MT, Prox J, Lüllmann-Rauch R, Schmitz A, Schwanbeck R, Blobel CP, Jorissen E, de Strooper B, Niessen CM, Saftig P.

Development. 2011 Feb;138(3):495-505. doi: 10.1242/dev.055210.

3.

Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation.

Franzke CW, Cobzaru C, Triantafyllopoulou A, Löffek S, Horiuchi K, Threadgill DW, Kurz T, van Rooijen N, Bruckner-Tuderman L, Blobel CP.

J Exp Med. 2012 Jun 4;209(6):1105-19. doi: 10.1084/jem.20112258. Epub 2012 May 7. Erratum in: J Exp Med. 2012 Dec 17;209(13):2517.

4.

The potential role of impaired Notch signalling in atopic dermatitis.

Melnik BC.

Acta Derm Venereol. 2015 Jan;95(1):5-11. doi: 10.2340/00015555-1898. Review.

5.

Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin.

Dumortier A, Durham AD, Di Piazza M, Vauclair S, Koch U, Ferrand G, Ferrero I, Demehri S, Song LL, Farr AG, Leonard WJ, Kopan R, Miele L, Hohl D, Finke D, Radtke F.

PLoS One. 2010 Feb 18;5(2):e9258. doi: 10.1371/journal.pone.0009258.

6.

ADAM10 and ADAM17 have opposite roles during sprouting angiogenesis.

Caolo V, Swennen G, Chalaris A, Wagenaar A, Verbruggen S, Rose-John S, Molin DG, Vooijs M, Post MJ.

Angiogenesis. 2015 Jan;18(1):13-22. doi: 10.1007/s10456-014-9443-4. Epub 2014 Sep 14.

PMID:
25218057
7.

Selective use of ADAM10 and ADAM17 in activation of Notch1 signaling.

Bozkulak EC, Weinmaster G.

Mol Cell Biol. 2009 Nov;29(21):5679-95. doi: 10.1128/MCB.00406-09. Epub 2009 Aug 24.

8.

Smooth muscle cells relay acute pulmonary inflammation via distinct ADAM17/ErbB axes.

Dreymueller D, Martin C, Schumacher J, Groth E, Boehm JK, Reiss LK, Uhlig S, Ludwig A.

J Immunol. 2014 Jan 15;192(2):722-31. doi: 10.4049/jimmunol.1302496. Epub 2013 Dec 16.

9.

Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice.

Chalaris A, Adam N, Sina C, Rosenstiel P, Lehmann-Koch J, Schirmacher P, Hartmann D, Cichy J, Gavrilova O, Schreiber S, Jostock T, Matthews V, Häsler R, Becker C, Neurath MF, Reiss K, Saftig P, Scheller J, Rose-John S.

J Exp Med. 2010 Aug 2;207(8):1617-24. doi: 10.1084/jem.20092366. Epub 2010 Jul 5.

10.

A disintegrin and metalloproteinase 17 regulates TNF and TNFR1 levels in inflammation and liver regeneration in mice.

McMahan RS, Riehle KJ, Fausto N, Campbell JS.

Am J Physiol Gastrointest Liver Physiol. 2013 Jul 1;305(1):G25-34. doi: 10.1152/ajpgi.00326.2012. Epub 2013 May 2.

11.

Epidermal ADAM17 is dispensable for notch activation.

Groot AJ, Cobzaru C, Weber S, Saftig P, Blobel CP, Kopan R, Vooijs M, Franzke CW.

J Invest Dermatol. 2013 Sep;133(9):2286-8. doi: 10.1038/jid.2013.162. Epub 2013 Apr 3. No abstract available.

12.

TSLP expression: cellular sources, triggers, and regulatory mechanisms.

Takai T.

Allergol Int. 2012 Mar;61(1):3-17. doi: 10.2332/allergolint.11-RAI-0395. Epub 2012 Jan 25. Review.

13.

Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity.

Demehri S, Liu Z, Lee J, Lin MH, Crosby SD, Roberts CJ, Grigsby PW, Miner JH, Farr AG, Kopan R.

PLoS Biol. 2008 May 27;6(5):e123. doi: 10.1371/journal.pbio.0060123.

14.

TSLP expression induced via Toll-like receptor pathways in human keratinocytes.

Takai T, Chen X, Xie Y, Vu AT, Le TA, Kinoshita H, Kawasaki J, Kamijo S, Hara M, Ushio H, Baba T, Hiramatsu K, Ikeda S, Ogawa H, Okumura K.

Methods Enzymol. 2014;535:371-87. doi: 10.1016/B978-0-12-397925-4.00021-3.

PMID:
24377934
15.

Antagonistic effect of the inflammasome on thymic stromal lymphopoietin expression in the skin.

Schuepbach-Mallepell S, Philippe V, Brüggen MC, Watanabe H, Roques S, Baldeschi C, Gaide O.

J Allergy Clin Immunol. 2013 Dec;132(6):1348-57. doi: 10.1016/j.jaci.2013.06.033. Epub 2013 Aug 13.

PMID:
23953709
16.

Skin Barrier Defects Caused by Keratinocyte-Specific Deletion of ADAM17 or EGFR Are Based on Highly Similar Proteome and Degradome Alterations.

Tholen S, Wolf C, Mayer B, Knopf JD, Löffek S, Qian Y, Kizhakkedathu JN, Biniossek ML, Franzke CW, Schilling O.

J Proteome Res. 2016 May 6;15(5):1402-17. doi: 10.1021/acs.jproteome.5b00691. Epub 2016 Apr 21.

PMID:
27089454
17.

Constitutive expression and regulated release of the transmembrane chemokine CXCL16 in human and murine skin.

Scholz F, Schulte A, Adamski F, Hundhausen C, Mittag J, Schwarz A, Kruse ML, Proksch E, Ludwig A.

J Invest Dermatol. 2007 Jun;127(6):1444-55. Epub 2007 Mar 15.

18.

The ADAM family: Insights into Notch proteolysis.

Christian LM.

Fly (Austin). 2012 Jan-Mar;6(1):30-4. doi: 10.4161/fly.18823. Epub 2012 Jan 1. Review.

PMID:
22513479
19.

The role of metalloproteinase ADAM17 in regulating ICOS ligand-mediated humoral immune responses.

Marczynska J, Ozga A, Wlodarczyk A, Majchrzak-Gorecka M, Kulig P, Banas M, Michalczyk-Wetula D, Majewski P, Hutloff A, Schwarz J, Chalaris A, Scheller J, Rose-John S, Cichy J.

J Immunol. 2014 Sep 15;193(6):2753-63. doi: 10.4049/jimmunol.1302893. Epub 2014 Aug 8.

20.

Inducible deletion of the Blimp-1 gene in adult epidermis causes granulocyte-dominated chronic skin inflammation in mice.

Chiang MF, Yang SY, Lin IY, Hong JB, Lin SJ, Ying HY, Chen CM, Wu SY, Liu FT, Lin KI.

Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6476-81. doi: 10.1073/pnas.1219462110. Epub 2013 Apr 1.

Supplemental Content

Support Center