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Items: 1 to 20 of 179

1.

Genetic signatures of exceptional longevity in humans.

Sebastiani P, Solovieff N, Dewan AT, Walsh KM, Puca A, Hartley SW, Melista E, Andersen S, Dworkis DA, Wilk JB, Myers RH, Steinberg MH, Montano M, Baldwin CT, Hoh J, Perls TT.

PLoS One. 2012;7(1):e29848. doi: 10.1371/journal.pone.0029848. Epub 2012 Jan 18.

2.

Genetic signatures of exceptional longevity in humans.

Sebastiani P, Solovieff N, Puca A, Hartley SW, Melista E, Andersen S, Dworkis DA, Wilk JB, Myers RH, Steinberg MH, Montano M, Baldwin CT, Perls TT.

Science. 2010 Jul 1;2010. doi: 10.1126/science.1190532. Epub 2010 Jul 1. Retraction in: Sebastiani P, Solovieff N, Puca A, Hartley SW, Melista E, Andersen S, Dworkis DA, Wilk JB, Myers RH, Steinberg MH, Montano M, Baldwin CT, Perls TT. Science. 2011 Jul 22;333(6041):404.

3.

Genetic variation and human longevity.

Soerensen M.

Dan Med J. 2012 May;59(5):B4454.

PMID:
22549493
4.

Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.

Deelen J, Beekman M, Uh HW, Helmer Q, Kuningas M, Christiansen L, Kremer D, van der Breggen R, Suchiman HE, Lakenberg N, van den Akker EB, Passtoors WM, Tiemeier H, van Heemst D, de Craen AJ, Rivadeneira F, de Geus EJ, Perola M, van der Ouderaa FJ, Gunn DA, Boomsma DI, Uitterlinden AG, Christensen K, van Duijn CM, Heijmans BT, Houwing-Duistermaat JJ, Westendorp RG, Slagboom PE.

Aging Cell. 2011 Aug;10(4):686-98. doi: 10.1111/j.1474-9726.2011.00705.x. Epub 2011 May 6.

5.

FNDC5 (irisin) gene and exceptional longevity: a functional replication study with rs16835198 and rs726344 SNPs.

Sanchis-Gomar F, Garatachea N, He ZH, Pareja-Galeano H, Fuku N, Tian Y, Arai Y, Abe Y, Murakami H, Miyachi M, Yvert T, Santiago C, Venturini L, Fiuza-Luces C, Santos-Lozano A, Rodríguez-Romo G, Ricevuti G, Hirose N, Emanuele E, Lucia A.

Age (Dordr). 2014;36(6):9733. doi: 10.1007/s11357-014-9733-1. Epub 2014 Nov 27.

6.

Genome-Wide Scan Informed by Age-Related Disease Identifies Loci for Exceptional Human Longevity.

Fortney K, Dobriban E, Garagnani P, Pirazzini C, Monti D, Mari D, Atzmon G, Barzilai N, Franceschi C, Owen AB, Kim SK.

PLoS Genet. 2015 Dec 17;11(12):e1005728. doi: 10.1371/journal.pgen.1005728. eCollection 2015 Dec.

7.

Genetic variants in PVRL2-TOMM40-APOE region are associated with human longevity in a Han Chinese population.

Lu F, Guan H, Gong B, Liu X, Zhu R, Wang Y, Qian J, Zhou T, Lan X, Wang P, Lin Y, Ma S, Lin H, Zhu X, Chen R, Zhu X, Shi Y, Yang Z.

PLoS One. 2014 Jun 12;9(6):e99580. doi: 10.1371/journal.pone.0099580. eCollection 2014.

8.

Meta‐analysis of genetic variants associated with human exceptional longevity.

Sebastiani P, Bae H, Sun FX, Andersen SL, Daw EW, Malovini A, Kojima T, Hirose N, Schupf N, Puca A, Perls TT.

Aging (Albany NY). 2013 Sep;5(9):653-61.

9.

Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study.

Lunetta KL, D'Agostino RB Sr, Karasik D, Benjamin EJ, Guo CY, Govindaraju R, Kiel DP, Kelly-Hayes M, Massaro JM, Pencina MJ, Seshadri S, Murabito JM.

BMC Med Genet. 2007 Sep 19;8 Suppl 1:S13.

10.

Are centenarians genetically predisposed to lower disease risk?

Ruiz JR, Fiuza-Luces C, Buxens A, Cano-Nieto A, Gómez-Gallego F, Santiago C, Rodríguez-Romo G, Garatachea N, Lao JI, Morán M, Lucia A.

Age (Dordr). 2012 Oct;34(5):1269-83. Epub 2011 Sep 6.

11.

Variations of the angiotensin II type 1 receptor gene are associated with extreme human longevity.

Benigni A, Orisio S, Noris M, Iatropoulos P, Castaldi D, Kamide K, Rakugi H, Arai Y, Todeschini M, Ogliari G, Imai E, Gondo Y, Hirose N, Mari D, Remuzzi G.

Age (Dordr). 2013 Jun;35(3):993-1005. doi: 10.1007/s11357-012-9408-8. Epub 2012 May 9.

12.

Paraoxonase polymorphisms PON1 192 and 55 and longevity in Italian centenarians and Irish nonagenarians. A pooled analysis.

Rea IM, McKeown PP, McMaster D, Young IS, Patterson C, Savage MJ, Belton C, Marchegiani F, Olivieri F, Bonafe M, Franceschi C.

Exp Gerontol. 2004 Apr;39(4):629-35.

PMID:
15050299
13.

Genetic predisposition to elevated serum thyrotropin is associated with exceptional longevity.

Atzmon G, Barzilai N, Surks MI, Gabriely I.

J Clin Endocrinol Metab. 2009 Dec;94(12):4768-75. doi: 10.1210/jc.2009-0808. Epub 2009 Oct 16.

14.

Genetics of healthy aging and longevity.

Brooks-Wilson AR.

Hum Genet. 2013 Dec;132(12):1323-38. doi: 10.1007/s00439-013-1342-z. Epub 2013 Aug 8. Review.

15.

The rs1333049 polymorphism on locus 9p21.3 and extreme longevity in Spanish and Japanese cohorts.

Pinós T, Fuku N, Cámara Y, Arai Y, Abe Y, Rodríguez-Romo G, Garatachea N, Santos-Lozano A, Miro-Casas E, Ruiz-Meana M, Otaegui I, Murakami H, Miyachi M, Garcia-Dorado D, Hinohara K, Andreu AL, Kimura A, Hirose N, Lucia A.

Age (Dordr). 2014 Apr;36(2):933-43. doi: 10.1007/s11357-013-9593-0. Epub 2013 Oct 28.

16.

Interleukin 6-174 G/C promoter gene polymorphism in centenarians: no evidence of association with human longevity or interaction with apolipoprotein E alleles.

Capurso C, Solfrizzi V, D'Introno A, Colacicco AM, Capurso SA, Semeraro C, Capurso A, Panza F.

Exp Gerontol. 2004 Jul;39(7):1109-14.

PMID:
15236771
17.

Polygenic effects of common single-nucleotide polymorphisms on life span: when association meets causality.

Yashin AI, Wu D, Arbeev KG, Ukraintseva SV.

Rejuvenation Res. 2012 Aug;15(4):381-94. doi: 10.1089/rej.2011.1257. Epub 2012 Apr 25.

18.

PTK2 rs7460 and rs7843014 polymorphisms and exceptional longevity: a functional replication study.

Garatachea N, Fuku N, He ZH, Tian Y, Arai Y, Abe Y, Murakami H, Miyachi M, Yvert T, Venturini L, Santiago C, Santos-Lozano A, Rodríguez G, Ricevuti G, Pareja-Galeano H, Sanchis-Gomar F, Emanuele E, Hirose N, Lucia A.

Rejuvenation Res. 2014 Oct;17(5):430-8. doi: 10.1089/rej.2014.1570.

19.

Buffering mechanisms in aging: a systems approach toward uncovering the genetic component of aging.

Bergman A, Atzmon G, Ye K, MacCarthy T, Barzilai N.

PLoS Comput Biol. 2007 Aug;3(8):e170. Epub 2007 Jul 18.

20.

The genetics of exceptional longevity: Insights from centenarians.

Santos-Lozano A, Santamarina A, Pareja-Galeano H, Sanchis-Gomar F, Fiuza-Luces C, Cristi-Montero C, Bernal-Pino A, Lucia A, Garatachea N.

Maturitas. 2016 Aug;90:49-57. doi: 10.1016/j.maturitas.2016.05.006. Epub 2016 May 10. Review.

PMID:
27282794

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