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Items: 1 to 20 of 99

1.

What is complex about complex disorders?

Mitchell KJ.

Genome Biol. 2012 Jan 23;13(1):237. doi: 10.1186/gb-2012-13-1-237.

2.

Genome-wide association studies (GWAS) in complex diseases: advantages and limitations.

Riancho JA.

Reumatol Clin. 2012 Mar-Apr;8(2):56-7. doi: 10.1016/j.reuma.2011.07.005. Epub 2011 Nov 15. No abstract available.

3.

The role of genes in disease: beware of simplistic interpretations!

[No authors listed]

Prescrire Int. 2009 Dec;18(104):279-82.

PMID:
20027720
4.

Genome-wide association studies for complex traits: consensus, uncertainty and challenges.

McCarthy MI, Abecasis GR, Cardon LR, Goldstein DB, Little J, Ioannidis JP, Hirschhorn JN.

Nat Rev Genet. 2008 May;9(5):356-69. doi: 10.1038/nrg2344. Review.

PMID:
18398418
5.

Genomics and medicine. Dissecting human disease in the postgenomic era.

Peltonen L, McKusick VA.

Science. 2001 Feb 16;291(5507):1224-9. No abstract available.

PMID:
11233446
6.

[Genes and environment].

Feingold J.

J Soc Biol. 2000;194(1):5-8. Review. French.

PMID:
11107542
7.

[Genetic analyses for identifying molecular mechanisms in autism spectrum disorders].

Chiocchetti A, Klauck SM.

Z Kinder Jugendpsychiatr Psychother. 2011 Mar;39(2):101-11. doi: 10.1024/1422-4917/a000096. Review. German.

PMID:
21442598
8.

Common disorders are quantitative traits.

Plomin R, Haworth CM, Davis OS.

Nat Rev Genet. 2009 Dec;10(12):872-8. doi: 10.1038/nrg2670. Epub 2009 Oct 27. Review.

PMID:
19859063
9.

The contribution of genetic variants to disease depends on the ruler.

Witte JS, Visscher PM, Wray NR.

Nat Rev Genet. 2014 Nov;15(11):765-76. doi: 10.1038/nrg3786. Epub 2014 Sep 16. Review.

10.

From monogenic to polygenic obesity: recent advances.

Hinney A, Vogel CI, Hebebrand J.

Eur Child Adolesc Psychiatry. 2010 Mar;19(3):297-310. doi: 10.1007/s00787-010-0096-6. Epub 2010 Feb 3. Review.

11.

Genome-wide association studies for common diseases and complex traits.

Hirschhorn JN, Daly MJ.

Nat Rev Genet. 2005 Feb;6(2):95-108. Review.

PMID:
15716906
12.

Lessons from model organisms: phenotypic robustness and missing heritability in complex disease.

Queitsch C, Carlson KD, Girirajan S.

PLoS Genet. 2012;8(11):e1003041. doi: 10.1371/journal.pgen.1003041. Epub 2012 Nov 15.

13.

Mathematical model for polygenic diseases.

Datta SS.

Med Hypotheses. 2005;64(6):1240-1. No abstract available.

PMID:
15823728
14.

Height matters-from monogenic disorders to normal variation.

Durand C, Rappold GA.

Nat Rev Endocrinol. 2013 Mar;9(3):171-7. doi: 10.1038/nrendo.2012.251. Epub 2013 Jan 22. Review.

PMID:
23337954
15.

Finding genes influencing susceptibility to complex diseases in the post-genome era.

Rannala B.

Am J Pharmacogenomics. 2001;1(3):203-21. Review.

PMID:
12083968
16.

Genetic-linkage mapping of complex hereditary disorders to a whole-genome molecular-interaction network.

Iossifov I, Zheng T, Baron M, Gilliam TC, Rzhetsky A.

Genome Res. 2008 Jul;18(7):1150-62. doi: 10.1101/gr.075622.107. Epub 2008 Apr 16.

17.

Genetics of endometriosis: heritability and candidate genes.

Bischoff F, Simpson JL.

Best Pract Res Clin Obstet Gynaecol. 2004 Apr;18(2):219-32. Review.

PMID:
15157639
18.

Genetics of complex diseases: variations on a theme.

Mellerup E, Møller GL, Koefoed P.

Med Hypotheses. 2012 Jun;78(6):732-4. doi: 10.1016/j.mehy.2012.02.019. Epub 2012 Mar 17.

PMID:
22424717
19.

Heterozygosity for a Mendelian disorder as a risk factor for complex disease.

Sidransky E.

Clin Genet. 2006 Oct;70(4):275-82. Review.

PMID:
16965318
20.

Nicotinic acetylcholine receptors in human genetic disease.

Schaaf CP.

Genet Med. 2014 Sep;16(9):649-56. doi: 10.1038/gim.2014.9. Epub 2014 Feb 20. Review.

PMID:
24556925

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