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Items: 1 to 20 of 71

1.

Mediator complex regulates alternative mRNA processing via the MED23 subunit.

Huang Y, Li W, Yao X, Lin QJ, Yin JW, Liang Y, Heiner M, Tian B, Hui J, Wang G.

Mol Cell. 2012 Feb 24;45(4):459-69. doi: 10.1016/j.molcel.2011.12.022. Epub 2012 Jan 19.

2.

Mediator MED23 regulates basal transcription in vivo via an interaction with P-TEFb.

Wang W, Yao X, Huang Y, Hu X, Liu R, Hou D, Chen R, Wang G.

Transcription. 2013 Jan-Feb;4(1):39-51. doi: 10.4161/trns.22874.

3.

Diverse roles of hnRNP L in mammalian mRNA processing: a combined microarray and RNAi analysis.

Hung LH, Heiner M, Hui J, Schreiner S, Benes V, Bindereif A.

RNA. 2008 Feb;14(2):284-96. Epub 2007 Dec 11.

4.

The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination.

Yao X, Tang Z, Fu X, Yin J, Liang Y, Li C, Li H, Tian Q, Roeder RG, Wang G.

EMBO J. 2015 Dec 2;34(23):2885-902. doi: 10.15252/embj.201591279. Epub 2015 Sep 1.

5.

HnRNP C, YB-1 and hnRNP L coordinately enhance skipping of human MUSK exon 10 to generate a Wnt-insensitive MuSK isoform.

Nasrin F, Rahman MA, Masuda A, Ohe K, Takeda J, Ohno K.

Sci Rep. 2014 Oct 30;4:6841. doi: 10.1038/srep06841.

7.

HnRNP L represses exon splicing via a regulated exonic splicing silencer.

Rothrock CR, House AE, Lynch KW.

EMBO J. 2005 Aug 3;24(15):2792-802. Epub 2005 Jul 7.

8.

hnRNP U enhances caspase-9 splicing and is modulated by AKT-dependent phosphorylation of hnRNP L.

Vu NT, Park MA, Shultz JC, Goehe RW, Hoeferlin LA, Shultz MD, Smith SA, Lynch KW, Chalfant CE.

J Biol Chem. 2013 Mar 22;288(12):8575-84. doi: 10.1074/jbc.M112.443333. Epub 2013 Feb 8.

9.

HnRNP L stimulates splicing of the eNOS gene by binding to variable-length CA repeats.

Hui J, Stangl K, Lane WS, Bindereif A.

Nat Struct Biol. 2003 Jan;10(1):33-7.

PMID:
12447348
10.

hnRNP L regulates the tumorigenic capacity of lung cancer xenografts in mice via caspase-9 pre-mRNA processing.

Goehe RW, Shultz JC, Murudkar C, Usanovic S, Lamour NF, Massey DH, Zhang L, Camidge DR, Shay JW, Minna JD, Chalfant CE.

J Clin Invest. 2010 Nov;120(11):3923-39. doi: 10.1172/JCI43552. Epub 2010 Oct 25.

11.

hnRNP L and hnRNP A1 induce extended U1 snRNA interactions with an exon to repress spliceosome assembly.

Chiou NT, Shankarling G, Lynch KW.

Mol Cell. 2013 Mar 7;49(5):972-82. doi: 10.1016/j.molcel.2012.12.025. Epub 2013 Feb 7.

12.

HnRNP L and L-like cooperate in multiple-exon regulation of CD45 alternative splicing.

Preussner M, Schreiner S, Hung LH, Porstner M, Jäck HM, Benes V, Rätsch G, Bindereif A.

Nucleic Acids Res. 2012 Jul;40(12):5666-78. doi: 10.1093/nar/gks221. Epub 2012 Mar 8.

14.

hnRNP A1 and the SR proteins ASF/SF2 and SC35 have antagonistic functions in splicing of beta-tropomyosin exon 6B.

Expert-Bezançon A, Sureau A, Durosay P, Salesse R, Groeneveld H, Lecaer JP, Marie J.

J Biol Chem. 2004 Sep 10;279(37):38249-59. Epub 2004 Jun 18.

15.

Alternative splicing controlled by heterogeneous nuclear ribonucleoprotein L regulates development, proliferation, and migration of thymic pre-T cells.

Gaudreau MC, Heyd F, Bastien R, Wilhelm B, Möröy T.

J Immunol. 2012 Jun 1;188(11):5377-88. doi: 10.4049/jimmunol.1103142. Epub 2012 Apr 20.

16.

Mediator subunit 23 overexpression as a novel target for suppressing proliferation and tumorigenesis in hepatocellular carcinoma.

Guo Y, Wang J, Li H, Liu W, Chen D, Zhao K, Liang X, Zhang Q, Yang Y, Chen G.

J Gastroenterol Hepatol. 2015 Jun;30(6):1094-103. doi: 10.1111/jgh.12923.

PMID:
25684393
17.

Adenovirus L-E1A activates transcription through mediator complex-dependent recruitment of the super elongation complex.

Vijayalingam S, Chinnadurai G.

J Virol. 2013 Mar;87(6):3425-34. doi: 10.1128/JVI.03046-12. Epub 2013 Jan 9.

18.

Transcriptome-wide RNA interaction profiling reveals physical and functional targets of hnRNP L in human T cells.

Shankarling G, Cole BS, Mallory MJ, Lynch KW.

Mol Cell Biol. 2014 Jan;34(1):71-83. doi: 10.1128/MCB.00740-13. Epub 2013 Oct 28.

19.

T-cells null for the MED23 subunit of mediator express decreased levels of KLF2 and inefficiently populate the peripheral lymphoid organs.

Kasper LH, Fukuyama T, Brindle PK.

PLoS One. 2014 Jul 23;9(7):e102076. doi: 10.1371/journal.pone.0102076. eCollection 2014.

20.

hnRNP L regulates differences in expression of mouse integrin alpha2beta1.

Cheli Y, Kunicki TJ.

Blood. 2006 Jun 1;107(11):4391-8. Epub 2006 Feb 2.

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