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Items: 1 to 20 of 141

1.

Structural and inhibition studies of the RNase H function of xenotropic murine leukemia virus-related virus reverse transcriptase.

Kirby KA, Marchand B, Ong YT, Ndongwe TP, Hachiya A, Michailidis E, Leslie MD, Sietsema DV, Fetterly TL, Dorst CA, Singh K, Wang Z, Parniak MA, Sarafianos SG.

Antimicrob Agents Chemother. 2012 Apr;56(4):2048-61. doi: 10.1128/AAC.06000-11. Epub 2012 Jan 17.

2.

Biochemical, inhibition and inhibitor resistance studies of xenotropic murine leukemia virus-related virus reverse transcriptase.

Ndongwe TP, Adedeji AO, Michailidis E, Ong YT, Hachiya A, Marchand B, Ryan EM, Rai DK, Kirby KA, Whatley AS, Burke DH, Johnson M, Ding S, Zheng YM, Liu SL, Kodama E, Delviks-Frankenberry KA, Pathak VK, Mitsuya H, Parniak MA, Singh K, Sarafianos SG.

Nucleic Acids Res. 2012 Jan;40(1):345-59. doi: 10.1093/nar/gkr694. Epub 2011 Sep 8.

3.

Intrinsic DNA synthesis fidelity of xenotropic murine leukemia virus-related virus reverse transcriptase.

Barrioluengo V, Wang Y, Le Grice SF, Menéndez-Arias L.

FEBS J. 2012 Apr;279(8):1433-44. doi: 10.1111/j.1742-4658.2012.08532.x. Epub 2012 Mar 16.

4.

Crystal structure of xenotropic murine leukaemia virus-related virus (XMRV) ribonuclease H.

Kim JH, Kang S, Jung SK, Yu KR, Chung SJ, Chung BH, Erikson RL, Kim BY, Kim SJ.

Biosci Rep. 2012 Oct;32(5):455-63. doi: 10.1042/BSR20120028.

5.

RNase H activity: structure, specificity, and function in reverse transcription.

Schultz SJ, Champoux JJ.

Virus Res. 2008 Jun;134(1-2):86-103. doi: 10.1016/j.virusres.2007.12.007. Epub 2008 Feb 7. Review.

6.

Murine leukemia virus reverse transcriptase: structural comparison with HIV-1 reverse transcriptase.

Coté ML, Roth MJ.

Virus Res. 2008 Jun;134(1-2):186-202. doi: 10.1016/j.virusres.2008.01.001. Epub 2008 Feb 21. Review.

9.

Crystal structures of the reverse transcriptase-associated ribonuclease H domain of xenotropic murine leukemia-virus related virus.

Zhou D, Chung S, Miller M, Grice SF, Wlodawer A.

J Struct Biol. 2012 Mar;177(3):638-45. doi: 10.1016/j.jsb.2012.02.006. Epub 2012 Feb 16.

10.

Inhibition of the ribonuclease H and DNA polymerase activities of HIV-1 reverse transcriptase by N-(4-tert-butylbenzoyl)-2-hydroxy-1-naphthaldehyde hydrazone.

Borkow G, Fletcher RS, Barnard J, Arion D, Motakis D, Dmitrienko GI, Parniak MA.

Biochemistry. 1997 Mar 18;36(11):3179-85.

PMID:
9115994
12.

Mutational analysis of Tyr-501 of HIV-1 reverse transcriptase. Effects on ribonuclease H activity and inhibition of this activity by N-acylhydrazones.

Arion D, Sluis-Cremer N, Min KL, Abram ME, Fletcher RS, Parniak MA.

J Biol Chem. 2002 Jan 11;277(2):1370-4. Epub 2001 Oct 29.

14.

Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6.

Corona A, Meleddu R, Esposito F, Distinto S, Bianco G, Masaoka T, Maccioni E, Menéndez-Arias L, Alcaro S, Le Grice SF, Tramontano E.

PLoS One. 2016 Jan 22;11(1):e0147225. doi: 10.1371/journal.pone.0147225. eCollection 2016.

15.

Inhibition of HIV-1 reverse transcriptase-catalyzed DNA strand transfer reactions by 4-chlorophenylhydrazone of mesoxalic acid.

Davis WR, Tomsho J, Nikam S, Cook EM, Somand D, Peliska JA.

Biochemistry. 2000 Nov 21;39(46):14279-91.

PMID:
11087377
16.

Structural models of ribonuclease H domains in reverse transcriptases from retroviruses.

Nakamura H, Katayanagi K, Morikawa K, Ikehara M.

Nucleic Acids Res. 1991 Apr 25;19(8):1817-23.

17.

Metal binding and activation of the ribonuclease H domain from moloney murine leukemia virus.

Goedken ER, Marqusee S.

Protein Eng. 1999 Nov;12(11):975-80.

PMID:
10585503
18.

Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases.

Esposito F, Kharlamova T, Distinto S, Zinzula L, Cheng YC, Dutschman G, Floris G, Markt P, Corona A, Tramontano E.

FEBS J. 2011 May;278(9):1444-57. doi: 10.1111/j.1742-4658.2011.08057.x. Epub 2011 Mar 16.

19.

Dissecting the effects of DNA polymerase and ribonuclease H inhibitor combinations on HIV-1 reverse-transcriptase activities.

Shaw-Reid CA, Feuston B, Munshi V, Getty K, Krueger J, Hazuda DJ, Parniak MA, Miller MD, Lewis D.

Biochemistry. 2005 Feb 8;44(5):1595-606.

PMID:
15683243
20.

Design, synthesis, biochemical, and antiviral evaluations of C6 benzyl and C6 biarylmethyl substituted 2-hydroxylisoquinoline-1,3-diones: dual inhibition against HIV reverse transcriptase-associated RNase H and polymerase with antiviral activities.

Vernekar SK, Liu Z, Nagy E, Miller L, Kirby KA, Wilson DJ, Kankanala J, Sarafianos SG, Parniak MA, Wang Z.

J Med Chem. 2015 Jan 22;58(2):651-64. doi: 10.1021/jm501132s. Epub 2014 Dec 30.

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