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Reduced DICER1 elicits an interferon response in endometrial cancer cells.

Chiappinelli KB, Haynes BC, Brent MR, Goodfellow PJ.

Mol Cancer Res. 2012 Mar;10(3):316-25. doi: 10.1158/1541-7786.MCR-11-0520. Epub 2012 Jan 17.


Cancer-associated somatic DICER1 hotspot mutations cause defective miRNA processing and reverse-strand expression bias to predominantly mature 3p strands through loss of 5p strand cleavage.

Anglesio MS, Wang Y, Yang W, Senz J, Wan A, Heravi-Moussavi A, Salamanca C, Maines-Bandiera S, Huntsman DG, Morin GB.

J Pathol. 2013 Feb;229(3):400-9. doi: 10.1002/path.4135.


Recurrent DICER1 hotspot mutations in endometrial tumours and their impact on microRNA biogenesis.

Chen J, Wang Y, McMonechy MK, Anglesio MS, Yang W, Senz J, Maines-Bandiera S, Rosner J, Trigo-Gonzalez G, Grace Cheng SW, Kim J, Matzuk MM, Morin GB, Huntsman DG.

J Pathol. 2015 Oct;237(2):215-25. doi: 10.1002/path.4569. Epub 2015 Jul 6.


Dicer1-mediated miRNA processing shapes the mRNA profile and function of murine platelets.

Rowley JW, Chappaz S, Corduan A, Chong MM, Campbell R, Khoury A, Manne BK, Wurtzel JG, Michael JV, Goldfinger LE, Mumaw MM, Nieman MT, Kile BT, Provost P, Weyrich AS.

Blood. 2016 Apr 7;127(14):1743-51. doi: 10.1182/blood-2015-07-661371. Epub 2016 Jan 14.


A precursor microRNA in a cancer cell nucleus: get me out of here!

Melo SA, Esteller M.

Cell Cycle. 2011 Mar 15;10(6):922-5. Epub 2011 Mar 15.


miR-130b is an EMT-related microRNA that targets DICER1 for aggression in endometrial cancer.

Li BL, Lu C, Lu W, Yang TT, Qu J, Hong X, Wan XP.

Med Oncol. 2013 Mar;30(1):484. doi: 10.1007/s12032-013-0484-0. Epub 2013 Feb 8.


Comprehensive analysis of microRNA (miRNA) targets in breast cancer cells.

Fan M, Krutilina R, Sun J, Sethuraman A, Yang CH, Wu ZH, Yue J, Pfeffer LM.

J Biol Chem. 2013 Sep 20;288(38):27480-93. doi: 10.1074/jbc.M113.491803. Epub 2013 Aug 6.


Clinicopathological and prognostic significance of microRNA-107 and its relationship to DICER1 mRNA expression in gastric cancer.

Inoue T, Iinuma H, Ogawa E, Inaba T, Fukushima R.

Oncol Rep. 2012 Jun;27(6):1759-64. doi: 10.3892/or.2012.1709. Epub 2012 Mar 7.


Stop the dicing in hematopoiesis: what have we learned?

Alemdehy MF, Erkeland SJ.

Cell Cycle. 2012 Aug 1;11(15):2799-807. doi: 10.4161/cc.21077. Epub 2012 Aug 1.


The use of miRNA microarrays for the analysis of cancer samples with global miRNA decrease.

Wu D, Hu Y, Tong S, Williams BR, Smyth GK, Gantier MP.

RNA. 2013 Jul;19(7):876-88. doi: 10.1261/rna.035055.112. Epub 2013 May 24.


RNA-binding protein AUF1 represses Dicer expression.

Abdelmohsen K, Tominaga-Yamanaka K, Srikantan S, Yoon JH, Kang MJ, Gorospe M.

Nucleic Acids Res. 2012 Dec;40(22):11531-44. doi: 10.1093/nar/gks930. Epub 2012 Oct 11.


Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells.

Ungvari Z, Tucsek Z, Sosnowska D, Toth P, Gautam T, Podlutsky A, Csiszar A, Losonczy G, Valcarcel-Ares MN, Sonntag WE, Csiszar A.

J Gerontol A Biol Sci Med Sci. 2013 Aug;68(8):877-91. doi: 10.1093/gerona/gls242. Epub 2012 Dec 13.


MicroRNA-107, an oncogene microRNA that regulates tumour invasion and metastasis by targeting DICER1 in gastric cancer.

Li X, Zhang Y, Shi Y, Dong G, Liang J, Han Y, Wang X, Zhao Q, Ding J, Wu K, Fan D.

J Cell Mol Med. 2011 Sep;15(9):1887-95. doi: 10.1111/j.1582-4934.2010.01194.x.


Overexpression of DICER1 induced by the upregulation of GATA1 contributes to the proliferation and apoptosis of leukemia cells.

Bai Y, Qiu GR, Zhou F, Gong LY, Gao F, Sun KL.

Int J Oncol. 2013 Apr;42(4):1317-24. doi: 10.3892/ijo.2013.1831. Epub 2013 Feb 19.


Deregulated sex chromosome gene expression with male germ cell-specific loss of Dicer1.

Greenlee AR, Shiao MS, Snyder E, Buaas FW, Gu T, Stearns TM, Sharma M, Murchison EP, Puente GC, Braun RE.

PLoS One. 2012;7(10):e46359. doi: 10.1371/journal.pone.0046359. Epub 2012 Oct 4.


MiR-192 directly binds and regulates Dicer1 expression in neuroblastoma.

Feinberg-Gorenshtein G, Guedj A, Shichrur K, Jeison M, Luria D, Kodman Y, Ash S, Feinmesser M, Edry L, Shomron N, Weizman A, Yaniv I, Avigad S.

PLoS One. 2013 Nov 1;8(11):e78713. doi: 10.1371/journal.pone.0078713. eCollection 2013.


Low DICER1 expression is associated with attenuated neutrophil differentiation and autophagy of NB4 APL cells.

Wampfler J, Federzoni EA, Torbett BE, Fey MF, Tschan MP.

J Leukoc Biol. 2015 Sep;98(3):357-63. doi: 10.1189/jlb.1AB0514-258R. Epub 2015 May 19.


DICER1 regulated let-7 expression levels in p53-induced cancer repression requires cyclin D1.

Sun X, Tang SC, Xu C, Wang C, Qin S, Du N, Liu J, Zhang Y, Li X, Luo G, Zhou J, Xu F, Ren H.

J Cell Mol Med. 2015 Jun;19(6):1357-65. doi: 10.1111/jcmm.12522. Epub 2015 Feb 20.


High copy number variation of cancer-related microRNA genes and frequent amplification of DICER1 and DROSHA in lung cancer.

Czubak K, Lewandowska MA, Klonowska K, Roszkowski K, Kowalewski J, Figlerowicz M, Kozlowski P.

Oncotarget. 2015 Sep 15;6(27):23399-416.


Silencing of Dicer1 temporally separates pro- and anti-apoptotic signaling and confers susceptibility to chemotherapy in p53 mutated cells.

Nekova TS, Kneitz S, Einsele H, Stuhler G.

Cell Cycle. 2014;13(14):2192-8. doi: 10.4161/cc.29216. Epub 2014 May 20.

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