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Items: 1 to 20 of 102

1.

Effect of cigarette smoke exposure and structural modifications on the α-1 Antitrypsin interaction with caspases.

Lockett AD, Van Demark M, Gu Y, Schweitzer KS, Sigua N, Kamocki K, Fijalkowska I, Garrison J, Fisher AJ, Serban K, Wise RA, Flotte TR, Mueller C, Presson RG Jr, Petrache HI, Tuder RM, Petrache I.

Mol Med. 2012 May 9;18:445-54. doi: 10.2119/molmed.2011.00207.

2.

alpha-1 antitrypsin inhibits caspase-3 activity, preventing lung endothelial cell apoptosis.

Petrache I, Fijalkowska I, Medler TR, Skirball J, Cruz P, Zhen L, Petrache HI, Flotte TR, Tuder RM.

Am J Pathol. 2006 Oct;169(4):1155-66.

3.

Lung disease associated with alpha1-antitrypsin deficiency.

Tuder RM, Janciauskiene SM, Petrache I.

Proc Am Thorac Soc. 2010 Nov;7(6):381-6. doi: 10.1513/pats.201002-020AW. Review.

4.

Mechanism of alpha-1 antitrypsin endocytosis by lung endothelium.

Sohrab S, Petrusca DN, Lockett AD, Schweitzer KS, Rush NI, Gu Y, Kamocki K, Garrison J, Petrache I.

FASEB J. 2009 Sep;23(9):3149-58. doi: 10.1096/fj.09-129304. Epub 2009 May 7.

5.

Alpha-1 Antitrypsin and Lung Cell Apoptosis.

Serban KA, Petrache I.

Ann Am Thorac Soc. 2016 Apr;13 Suppl 2:S146-9. doi: 10.1513/AnnalsATS.201505-312KV.

6.

Scavenger receptor class B, type I-mediated uptake of A1AT by pulmonary endothelial cells.

Lockett AD, Petrusca DN, Justice MJ, Poirier C, Serban KA, Rush NI, Kamocka M, Predescu D, Predescu S, Petrache I.

Am J Physiol Lung Cell Mol Physiol. 2015 Aug 15;309(4):L425-34. doi: 10.1152/ajplung.00376.2014. Epub 2015 Jun 19.

7.
8.

Alpha-1 antitrypsin supplementation improves alveolar macrophages efferocytosis and phagocytosis following cigarette smoke exposure.

Serban KA, Petrusca DN, Mikosz A, Poirier C, Lockett AD, Saint L, Justice MJ, Twigg HL 3rd, Campos MA, Petrache I.

PLoS One. 2017 Apr 27;12(4):e0176073. doi: 10.1371/journal.pone.0176073. eCollection 2017.

9.

TLR4 deficiency promotes autophagy during cigarette smoke-induced pulmonary emphysema.

An CH, Wang XM, Lam HC, Ifedigbo E, Washko GR, Ryter SW, Choi AM.

Am J Physiol Lung Cell Mol Physiol. 2012 Nov 1;303(9):L748-57. doi: 10.1152/ajplung.00102.2012. Epub 2012 Sep 14.

10.

α1-Antitrypsin activates protein phosphatase 2A to counter lung inflammatory responses.

Geraghty P, Eden E, Pillai M, Campos M, McElvaney NG, Foronjy RF.

Am J Respir Crit Care Med. 2014 Dec 1;190(11):1229-42. doi: 10.1164/rccm.201405-0872OC.

11.

alpha-1-Antitrypsin ameliorates cigarette smoke-induced emphysema in the mouse.

Churg A, Wang RD, Xie C, Wright JL.

Am J Respir Crit Care Med. 2003 Jul 15;168(2):199-207. Epub 2003 Apr 10.

PMID:
12689849
12.

The Anti-inflammatory Effect of Alpha-1 Antitrypsin in Rhinovirus-infected Human Airway Epithelial Cells.

Jiang D, Berman R, Wu Q, Stevenson C, Chu HW.

J Clin Cell Immunol. 2016 Dec;7(6). pii: 475. doi: 10.4172/2155-9899.1000475. Epub 2016 Dec 5.

13.

T cell depletion protects against alveolar destruction due to chronic cigarette smoke exposure in mice.

Podolin PL, Foley JP, Carpenter DC, Bolognese BJ, Logan GA, Long E 3rd, Harrison OJ, Walsh PT.

Am J Physiol Lung Cell Mol Physiol. 2013 Mar 1;304(5):L312-23. doi: 10.1152/ajplung.00152.2012. Epub 2013 Jan 4.

14.
15.

Oncostatin M and TNF-α Induce Alpha-1 Antitrypsin Production in Undifferentiated Adipose Stromal Cells.

Ni K, Umair Mukhtar Mian M, Meador C, Gill A, Barwinska D, Cao D, Justice MJ, Jiang D, Schaefer N, Schweitzer KS, Chu HW, March KL, Petrache I.

Stem Cells Dev. 2017 Oct 15;26(20):1468-1476. doi: 10.1089/scd.2017.0099. Epub 2017 Sep 21.

PMID:
28825379
16.

Alpha 1-antitrypsin does not inhibit human monocyte caspase-1.

Rahman MA, Mitra S, Sarkar A, Wewers MD.

PLoS One. 2015 Feb 6;10(2):e0117330. doi: 10.1371/journal.pone.0117330. eCollection 2015.

17.

Alpha1-antitrypsin suppresses TNF-alpha and MMP-12 production by cigarette smoke-stimulated macrophages.

Churg A, Wang X, Wang RD, Meixner SC, Pryzdial EL, Wright JL.

Am J Respir Cell Mol Biol. 2007 Aug;37(2):144-51. Epub 2007 Mar 29.

PMID:
17395890
18.

Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke-induced emphysema in mice.

Clauss M, Voswinckel R, Rajashekhar G, Sigua NL, Fehrenbach H, Rush NI, Schweitzer KS, Yildirim AÖ, Kamocki K, Fisher AJ, Gu Y, Safadi B, Nikam S, Hubbard WC, Tuder RM, Twigg HL 3rd, Presson RG, Sethi S, Petrache I.

J Clin Invest. 2011 Jun;121(6):2470-9. doi: 10.1172/JCI43881. Epub 2011 May 16. Erratum in: J Clin Invest. 2012 Jul 2;122(7):2703.

19.

Protective role for club cell secretory protein-16 (CC16) in the development of COPD.

Laucho-Contreras ME, Polverino F, Gupta K, Taylor KL, Kelly E, Pinto-Plata V, Divo M, Ashfaq N, Petersen H, Stripp B, Pilon AL, Tesfaigzi Y, Celli BR, Owen CA.

Eur Respir J. 2015 Jun;45(6):1544-56. doi: 10.1183/09031936.00134214. Epub 2015 Feb 19.

20.

PiSZ alpha-1 antitrypsin deficiency (AATD): pulmonary phenotype and prognosis relative to PiZZ AATD and PiMM COPD.

Green CE, Vayalapra S, Hampson JA, Mukherjee D, Stockley RA, Turner AM.

Thorax. 2015 Oct;70(10):939-45. doi: 10.1136/thoraxjnl-2015-206906. Epub 2015 Jul 3.

PMID:
26141072

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