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Items: 1 to 20 of 149

1.

Jmjd5, an H3K36me2 histone demethylase, modulates embryonic cell proliferation through the regulation of Cdkn1a expression.

Ishimura A, Minehata K, Terashima M, Kondoh G, Hara T, Suzuki T.

Development. 2012 Feb;139(4):749-59. doi: 10.1242/dev.074138. Epub 2012 Jan 12.

2.

Jmjd5 functions as a regulator of p53 signaling during mouse embryogenesis.

Ishimura A, Terashima M, Tange S, Suzuki T.

Cell Tissue Res. 2016 Mar;363(3):723-33. doi: 10.1007/s00441-015-2276-7. Epub 2015 Sep 3.

PMID:
26334721
3.

Epigenetic silencing of JMJD5 promotes the proliferation of hepatocellular carcinoma cells by down-regulating the transcription of CDKN1A 686.

Wu BH, Chen H, Cai CM, Fang JZ, Wu CC, Huang LY, Wang L, Han ZG.

Oncotarget. 2016 Feb 9;7(6):6847-63. doi: 10.18632/oncotarget.6867.

4.

Histone demethylase JMJD5 is essential for embryonic development.

Oh S, Janknecht R.

Biochem Biophys Res Commun. 2012 Mar 30;420(1):61-5. doi: 10.1016/j.bbrc.2012.02.115. Epub 2012 Feb 28. Erratum in: Biochem Biophys Res Commun. 2015 Sep 11;465(1):166.

PMID:
22402282
5.

Histone demethylase JMJD2B is required for tumor cell proliferation and survival and is overexpressed in gastric cancer.

Li W, Zhao L, Zang W, Liu Z, Chen L, Liu T, Xu D, Jia J.

Biochem Biophys Res Commun. 2011 Dec 16;416(3-4):372-8. doi: 10.1016/j.bbrc.2011.11.045. Epub 2011 Nov 19.

PMID:
22133676
6.

Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice.

Inagaki T, Tachibana M, Magoori K, Kudo H, Tanaka T, Okamura M, Naito M, Kodama T, Shinkai Y, Sakai J.

Genes Cells. 2009 Aug;14(8):991-1001. doi: 10.1111/j.1365-2443.2009.01326.x. Epub 2009 Jul 15.

7.

The histone demethylase Fbxl11/Kdm2a plays an essential role in embryonic development by repressing cell-cycle regulators.

Kawakami E, Tokunaga A, Ozawa M, Sakamoto R, Yoshida N.

Mech Dev. 2015 Feb;135:31-42. doi: 10.1016/j.mod.2014.10.001. Epub 2014 Oct 30.

8.

JMJD5 regulates cell cycle and pluripotency in human embryonic stem cells.

Zhu H, Hu S, Baker J.

Stem Cells. 2014 Aug;32(8):2098-110. doi: 10.1002/stem.1724.

9.

The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.

Toyokawa G, Cho HS, Iwai Y, Yoshimatsu M, Takawa M, Hayami S, Maejima K, Shimizu N, Tanaka H, Tsunoda T, Field HI, Kelly JD, Neal DE, Ponder BA, Maehara Y, Nakamura Y, Hamamoto R.

Cancer Prev Res (Phila). 2011 Dec;4(12):2051-61. doi: 10.1158/1940-6207.CAPR-11-0290. Epub 2011 Sep 19.

10.

Clipping of arginine-methylated histone tails by JMJD5 and JMJD7.

Liu H, Wang C, Lee S, Deng Y, Wither M, Oh S, Ning F, Dege C, Zhang Q, Liu X, Johnson AM, Zang J, Chen Z, Janknecht R, Hansen K, Marrack P, Li CY, Kappler JW, Hagman J, Zhang G.

Proc Natl Acad Sci U S A. 2017 Sep 12;114(37):E7717-E7726. doi: 10.1073/pnas.1706831114. Epub 2017 Aug 28.

11.

Structure of the JmjC-domain-containing protein JMJD5.

Wang H, Zhou X, Wu M, Wang C, Zhang X, Tao Y, Chen N, Zang J.

Acta Crystallogr D Biol Crystallogr. 2013 Oct;69(Pt 10):1911-20. doi: 10.1107/S0907444913016600. Epub 2013 Sep 20.

PMID:
24100311
12.

Role of yeast JmjC-domain containing histone demethylases in actively transcribed regions.

Kwon DW, Ahn SH.

Biochem Biophys Res Commun. 2011 Jul 8;410(3):614-9. doi: 10.1016/j.bbrc.2011.06.039. Epub 2011 Jun 12.

PMID:
21684259
13.

Fbxl10/Kdm2b deficiency accelerates neural progenitor cell death and leads to exencephaly.

Fukuda T, Tokunaga A, Sakamoto R, Yoshida N.

Mol Cell Neurosci. 2011 Mar;46(3):614-24. doi: 10.1016/j.mcn.2011.01.001. Epub 2011 Jan 8.

PMID:
21220025
14.

KR-POK interacts with p53 and represses its ability to activate transcription of p21WAF1/CDKN1A.

Jeon BN, Kim MK, Choi WI, Koh DI, Hong SY, Kim KS, Kim M, Yun CO, Yoon J, Choi KY, Lee KR, Nephew KP, Hur MW.

Cancer Res. 2012 Mar 1;72(5):1137-48. doi: 10.1158/0008-5472.CAN-11-2433. Epub 2012 Jan 17.

15.

The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36.

Klose RJ, Yamane K, Bae Y, Zhang D, Erdjument-Bromage H, Tempst P, Wong J, Zhang Y.

Nature. 2006 Jul 20;442(7100):312-6. Epub 2006 May 28.

PMID:
16732292
16.

Identification and functional implication of nuclear localization signals in the N-terminal domain of JMJD5.

Huang X, Zhang L, Qi H, Shao J, Shen J.

Biochimie. 2013 Nov;95(11):2114-22. doi: 10.1016/j.biochi.2013.08.002. Epub 2013 Aug 12.

PMID:
23948433
17.

KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation.

Hsia DA, Tepper CG, Pochampalli MR, Hsia EY, Izumiya C, Huerta SB, Wright ME, Chen HW, Kung HJ, Izumiya Y.

Proc Natl Acad Sci U S A. 2010 May 25;107(21):9671-6. doi: 10.1073/pnas.1000401107. Epub 2010 May 10.

18.

JMJD5, a Jumonji C (JmjC) domain-containing protein, negatively regulates osteoclastogenesis by facilitating NFATc1 protein degradation.

Youn MY, Yokoyama A, Fujiyama-Nakamura S, Ohtake F, Minehata K, Yasuda H, Suzuki T, Kato S, Imai Y.

J Biol Chem. 2012 Apr 13;287(16):12994-3004. doi: 10.1074/jbc.M111.323105. Epub 2012 Feb 28.

19.

Crystal structure and functional analysis of JMJD5 indicate an alternate specificity and function.

Del Rizzo PA, Krishnan S, Trievel RC.

Mol Cell Biol. 2012 Oct;32(19):4044-52. doi: 10.1128/MCB.00513-12. Epub 2012 Jul 30.

20.

Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression.

Wissmann M, Yin N, Müller JM, Greschik H, Fodor BD, Jenuwein T, Vogler C, Schneider R, Günther T, Buettner R, Metzger E, Schüle R.

Nat Cell Biol. 2007 Mar;9(3):347-53. Epub 2007 Feb 4.

PMID:
17277772

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