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Items: 1 to 20 of 110

1.

Protein kinase C (PKC)ζ-mediated Gαq stimulation of ERK5 protein pathway in cardiomyocytes and cardiac fibroblasts.

García-Hoz C, Sánchez-Fernández G, García-Escudero R, Fernández-Velasco M, Palacios-García J, Ruiz-Meana M, Díaz-Meco MT, Leitges M, Moscat J, García-Dorado D, Boscá L, Mayor F Jr, Ribas C.

J Biol Chem. 2012 Mar 2;287(10):7792-802. doi: 10.1074/jbc.M111.282210. Epub 2012 Jan 9.

2.

G alpha(q) acts as an adaptor protein in protein kinase C zeta (PKCzeta)-mediated ERK5 activation by G protein-coupled receptors (GPCR).

García-Hoz C, Sánchez-Fernández G, Díaz-Meco MT, Moscat J, Mayor F, Ribas C.

J Biol Chem. 2010 Apr 30;285(18):13480-9. doi: 10.1074/jbc.M109.098699. Epub 2010 Mar 3.

3.

Protein Kinase C ζ Interacts with a Novel Binding Region of Gαq to Act as a Functional Effector.

Sánchez-Fernández G, Cabezudo S, Caballero Á, García-Hoz C, Tall GG, Klett J, Michnick SW, Mayor F Jr, Ribas C.

J Biol Chem. 2016 Apr 29;291(18):9513-25. doi: 10.1074/jbc.M115.684308. Epub 2016 Feb 17.

4.

ERK5 activation by Gq-coupled muscarinic receptors is independent of receptor internalization and β-arrestin recruitment.

Sánchez-Fernández G, Cabezudo S, García-Hoz C, Tobin AB, Mayor F Jr, Ribas C.

PLoS One. 2013 Dec 17;8(12):e84174. doi: 10.1371/journal.pone.0084174. eCollection 2013.

5.

G alpha(q)-mediated activation of GRK2 by mechanical stretch in cardiac myocytes: the role of protein kinase C.

Malhotra R, D'Souza KM, Staron ML, Birukov KG, Bodi I, Akhter SA.

J Biol Chem. 2010 Apr 30;285(18):13748-60. doi: 10.1074/jbc.M110.109272. Epub 2010 Mar 1. Retraction in: Malhotra R, D'Souza KM, Staron ML, Birukov KG, Bodi I, Akhter SA. J Biol Chem. 2016 Jul 1;291(27):14390.

8.

Selective loss of fine tuning of Gq/11 signaling by RGS2 protein exacerbates cardiomyocyte hypertrophy.

Zhang W, Anger T, Su J, Hao J, Xu X, Zhu M, Gach A, Cui L, Liao R, Mende U.

J Biol Chem. 2006 Mar 3;281(9):5811-20. Epub 2005 Dec 26.

10.

G(13)-mediated signaling pathway is required for pressure overload-induced cardiac remodeling and heart failure.

Takefuji M, Wirth A, Lukasova M, Takefuji S, Boettger T, Braun T, Althoff T, Offermanns S, Wettschureck N.

Circulation. 2012 Oct 16;126(16):1972-82. doi: 10.1161/CIRCULATIONAHA.112.109256. Epub 2012 Sep 12.

11.

PKCzeta decreases eNOS protein stability via inhibitory phosphorylation of ERK5.

Nigro P, Abe J, Woo CH, Satoh K, McClain C, O'Dell MR, Lee H, Lim JH, Li JD, Heo KS, Fujiwara K, Berk BC.

Blood. 2010 Sep 16;116(11):1971-9. doi: 10.1182/blood-2010-02-269134. Epub 2010 Jun 10.

12.

Protein kinase C epsilon-dependent extracellular signal-regulated kinase 5 phosphorylation and nuclear translocation involved in cardiomyocyte hypertrophy with angiotensin II stimulation.

Zhao Z, Wang W, Geng J, Wang L, Su G, Zhang Y, Ge Z, Kang W.

J Cell Biochem. 2010 Mar 1;109(4):653-62. doi: 10.1002/jcb.22441.

PMID:
20052676
13.

Galpha(12/13) mediates alpha(1)-adrenergic receptor-induced cardiac hypertrophy.

Maruyama Y, Nishida M, Sugimoto Y, Tanabe S, Turner JH, Kozasa T, Wada T, Nagao T, Kurose H.

Circ Res. 2002 Nov 15;91(10):961-9.

14.

Arrestin orchestrates crosstalk between G protein-coupled receptors to modulate the spatiotemporal activation of ERK MAPK.

Cervantes D, Crosby C, Xiang Y.

Circ Res. 2010 Jan 8;106(1):79-88. doi: 10.1161/CIRCRESAHA.109.198580. Epub 2009 Nov 19.

15.

Protein kinase D mediates mitogenic signaling by Gq-coupled receptors through protein kinase C-independent regulation of activation loop Ser744 and Ser748 phosphorylation.

Sinnett-Smith J, Jacamo R, Kui R, Wang YM, Young SH, Rey O, Waldron RT, Rozengurt E.

J Biol Chem. 2009 May 15;284(20):13434-45. doi: 10.1074/jbc.M806554200. Epub 2009 Mar 16.

16.

Cardiac-specific overexpression of diacylglycerol kinase zeta prevents Gq protein-coupled receptor agonist-induced cardiac hypertrophy in transgenic mice.

Arimoto T, Takeishi Y, Takahashi H, Shishido T, Niizeki T, Koyama Y, Shiga R, Nozaki N, Nakajima O, Nishimaru K, Abe J, Endoh M, Walsh RA, Goto K, Kubota I.

Circulation. 2006 Jan 3;113(1):60-6. Epub 2005 Dec 27.

17.

Diacylglycerol kinase zeta rescues G alpha q-induced heart failure in transgenic mice.

Niizeki T, Takeishi Y, Kitahara T, Arimoto T, Koyama Y, Goto K, Mende U, Kubota I.

Circ J. 2008 Feb;72(2):309-17.

18.

Gq-coupled receptor agonists mediate cardiac hypertrophy via the vasculature.

Keys JR, Greene EA, Koch WJ, Eckhart AD.

Hypertension. 2002 Nov;40(5):660-6.

19.

Fluid shear stress promotes osteoblast proliferation via the Gαq-ERK5 signaling pathway.

Bo Z, Bin G, Jing W, Cuifang W, Liping A, Jinglin M, Jin J, Xiaoyi T, Cong C, Ning D, Yayi X.

Connect Tissue Res. 2016 Jul;57(4):299-306. doi: 10.1080/03008207.2016.1181063. Epub 2016 Apr 26.

PMID:
27115838
20.

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