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Items: 1 to 20 of 160

1.

A naturally occurring rexinoid, honokiol, can serve as a regulator of various retinoid x receptor heterodimers.

Kotani H, Tanabe H, Mizukami H, Amagaya S, Inoue M.

Biol Pharm Bull. 2012;35(1):1-9.

2.

Rexinoids isolated from Sophora tonkinensis with a gene expression profile distinct from the synthetic rexinoid bexarotene.

Inoue M, Tanabe H, Nakashima K, Ishida Y, Kotani H.

J Nat Prod. 2014 Jul 25;77(7):1670-7. doi: 10.1021/np5002016. Epub 2014 Jun 24.

PMID:
24959987
3.

Identification of a naturally occurring rexinoid, honokiol, that activates the retinoid X receptor.

Kotani H, Tanabe H, Mizukami H, Makishima M, Inoue M.

J Nat Prod. 2010 Aug 27;73(8):1332-6. doi: 10.1021/np100120c.

PMID:
20695472
4.

Research resource: transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte-derived dendritic cells.

Széles L, Póliska S, Nagy G, Szatmari I, Szanto A, Pap A, Lindstedt M, Santegoets SJ, Rühl R, Dezsö B, Nagy L.

Mol Endocrinol. 2010 Nov;24(11):2218-31. doi: 10.1210/me.2010-0215. Epub 2010 Sep 22.

5.

Activation of the retinoid X receptor modulates angiotensin II-induced smooth muscle gene expression and inflammation in vascular smooth muscle cells.

Lehman AM, Montford JR, Horita H, Ostriker AC, Weiser-Evans MC, Nemenoff RA, Furgeson SB.

Mol Pharmacol. 2014 Nov;86(5):570-9. doi: 10.1124/mol.114.092163. Epub 2014 Aug 28.

6.

Modulation of RXR function through ligand design.

Pérez E, Bourguet W, Gronemeyer H, de Lera AR.

Biochim Biophys Acta. 2012 Jan;1821(1):57-69. doi: 10.1016/j.bbalip.2011.04.003. Epub 2011 Apr 16. Review.

PMID:
21515403
7.

Rexinoid bexarotene modulates triglyceride but not cholesterol metabolism via gene-specific permissivity of the RXR/LXR heterodimer in the liver.

Lalloyer F, Pedersen TA, Gross B, Lestavel S, Yous S, Vallez E, Gustafsson JA, Mandrup S, Fiévet C, Staels B, Tailleux A.

Arterioscler Thromb Vasc Biol. 2009 Oct;29(10):1488-95. doi: 10.1161/ATVBAHA.109.189506. Epub 2009 Jul 10.

8.

Retinoid and thiazolidinedione therapies in melanoma: an analysis of differential response based on nuclear hormone receptor expression.

Klopper JP, Sharma V, Berenz A, Hays WR, Loi M, Pugazhenthi U, Said S, Haugen BR.

Mol Cancer. 2009 Mar 6;8:16. doi: 10.1186/1476-4598-8-16.

9.

The rexinoid LG100754 is a novel RXR:PPARgamma agonist and decreases glucose levels in vivo.

Cesario RM, Klausing K, Razzaghi H, Crombie D, Rungta D, Heyman RA, Lala DS.

Mol Endocrinol. 2001 Aug;15(8):1360-9.

PMID:
11463859
10.

Genome-wide profiling of liver X receptor, retinoid X receptor, and peroxisome proliferator-activated receptor α in mouse liver reveals extensive sharing of binding sites.

Boergesen M, Pedersen TÅ, Gross B, van Heeringen SJ, Hagenbeek D, Bindesbøll C, Caron S, Lalloyer F, Steffensen KR, Nebb HI, Gustafsson JÅ, Stunnenberg HG, Staels B, Mandrup S.

Mol Cell Biol. 2012 Feb;32(4):852-67. doi: 10.1128/MCB.06175-11. Epub 2011 Dec 12.

11.

Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists.

Mukherjee R, Davies PJ, Crombie DL, Bischoff ED, Cesario RM, Jow L, Hamann LG, Boehm MF, Mondon CE, Nadzan AM, Paterniti JR Jr, Heyman RA.

Nature. 1997 Mar 27;386(6623):407-10.

PMID:
9121558
12.

Honokiol: a non-adipogenic PPARγ agonist from nature.

Atanasov AG, Wang JN, Gu SP, Bu J, Kramer MP, Baumgartner L, Fakhrudin N, Ladurner A, Malainer C, Vuorinen A, Noha SM, Schwaiger S, Rollinger JM, Schuster D, Stuppner H, Dirsch VM, Heiss EH.

Biochim Biophys Acta. 2013 Oct;1830(10):4813-9. doi: 10.1016/j.bbagen.2013.06.021. Epub 2013 Jun 27.

13.

Limited cooperation between peroxisome proliferator-activated receptors and retinoid X receptor agonists in sebocyte growth and development.

Kim MJ, Deplewski D, Ciletti N, Michel S, Reichert U, Rosenfield RL.

Mol Genet Metab. 2001 Nov;74(3):362-9.

PMID:
11708867
14.

Activation of RXR/PPARγ underlies neuroprotection by bexarotene in ischemic stroke.

Certo M, Endo Y, Ohta K, Sakurada S, Bagetta G, Amantea D.

Pharmacol Res. 2015 Dec;102:298-307. doi: 10.1016/j.phrs.2015.10.009. Epub 2015 Nov 4.

PMID:
26546745
15.

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling.

Yoshikawa T, Ide T, Shimano H, Yahagi N, Amemiya-Kudo M, Matsuzaka T, Yatoh S, Kitamine T, Okazaki H, Tamura Y, Sekiya M, Takahashi A, Hasty AH, Sato R, Sone H, Osuga J, Ishibashi S, Yamada N.

Mol Endocrinol. 2003 Jul;17(7):1240-54. Epub 2003 May 1.

PMID:
12730331
16.

Effects on gene expression in rat liver after administration of RXR agonists: UAB30, 4-methyl-UAB30, and Targretin (Bexarotene).

Vedell PT, Lu Y, Grubbs CJ, Yin Y, Jiang H, Bland KI, Muccio DD, Cvetkovic D, You M, Lubet R.

Mol Pharmacol. 2013 Mar;83(3):698-708. doi: 10.1124/mol.112.082404. Epub 2013 Jan 4.

17.

Distinct mechanisms of glucose lowering by specific agonists for peroxisomal proliferator activated receptor gamma and retinoic acid X receptors.

Li X, Hansen PA, Xi L, Chandraratna RA, Burant CF.

J Biol Chem. 2005 Nov 18;280(46):38317-27. Epub 2005 Sep 22.

18.

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling.

Ide T, Shimano H, Yoshikawa T, Yahagi N, Amemiya-Kudo M, Matsuzaka T, Nakakuki M, Yatoh S, Iizuka Y, Tomita S, Ohashi K, Takahashi A, Sone H, Gotoda T, Osuga J, Ishibashi S, Yamada N.

Mol Endocrinol. 2003 Jul;17(7):1255-67. Epub 2003 May 1.

PMID:
12730332
19.

Induced differentiation of acute myeloid leukemia cells by activation of retinoid X and liver X receptors.

Sanchez PV, Glantz ST, Scotland S, Kasner MT, Carroll M.

Leukemia. 2014 Apr;28(4):749-60. doi: 10.1038/leu.2013.202. Epub 2013 Jul 4.

PMID:
23823656
20.

Retinoid X Receptor Selective Agonists and their Synthetic Methods.

Wagner CE, Jurutka PW, Marshall PA, Heck MC.

Curr Top Med Chem. 2017;17(6):742-767. Review.

PMID:
27320333

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