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Items: 1 to 20 of 299

1.

Contribution of organic anion transporting polypeptide (OATP) 1B1 and OATP1B3 to hepatic uptake of nateglinide, and the prediction of drug-drug interactions via these transporters.

Takanohashi T, Kubo S, Arisaka H, Shinkai K, Ubukata K.

J Pharm Pharmacol. 2012 Feb;64(2):199-206. doi: 10.1111/j.2042-7158.2011.01389.x. Epub 2011 Nov 10.

PMID:
22221095
2.

Prediction of organic anion-transporting polypeptide 1B1- and 1B3-mediated hepatic uptake of statins based on transporter protein expression and activity data.

Kunze A, Huwyler J, Camenisch G, Poller B.

Drug Metab Dispos. 2014 Sep;42(9):1514-21. doi: 10.1124/dmd.114.058412. Epub 2014 Jul 2.

3.

Influence of non-steroidal anti-inflammatory drugs on organic anion transporting polypeptide (OATP) 1B1- and OATP1B3-mediated drug transport.

Kindla J, Müller F, Mieth M, Fromm MF, König J.

Drug Metab Dispos. 2011 Jun;39(6):1047-53. doi: 10.1124/dmd.110.037622. Epub 2011 Mar 9.

4.
6.

Interaction of digitalis-like compounds with liver uptake transporters NTCP, OATP1B1, and OATP1B3.

Gozalpour E, Greupink R, Wortelboer HM, Bilos A, Schreurs M, Russel FG, Koenderink JB.

Mol Pharm. 2014 Jun 2;11(6):1844-55. doi: 10.1021/mp400699p. Epub 2014 May 6.

PMID:
24754247
7.
8.

Sodium fluorescein is a probe substrate for hepatic drug transport mediated by OATP1B1 and OATP1B3.

De Bruyn T, Fattah S, Stieger B, Augustijns P, Annaert P.

J Pharm Sci. 2011 Nov;100(11):5018-30. doi: 10.1002/jps.22694. Epub 2011 Aug 11.

PMID:
21837650
9.

Predominant contribution of OATP1B3 to the hepatic uptake of telmisartan, an angiotensin II receptor antagonist, in humans.

Ishiguro N, Maeda K, Kishimoto W, Saito A, Harada A, Ebner T, Roth W, Igarashi T, Sugiyama Y.

Drug Metab Dispos. 2006 Jul;34(7):1109-15. Epub 2006 Apr 12.

10.

Expression and transport function of drug uptake transporters in differentiated HepaRG cells.

Kotani N, Maeda K, Debori Y, Camus S, Li R, Chesne C, Sugiyama Y.

Mol Pharm. 2012 Dec 3;9(12):3434-41. doi: 10.1021/mp300171p. Epub 2012 Nov 6.

PMID:
22897388
11.

Inhibition of hepatic uptake transporters by flavonoids.

Mandery K, Balk B, Bujok K, Schmidt I, Fromm MF, Glaeser H.

Eur J Pharm Sci. 2012 May 12;46(1-2):79-85. doi: 10.1016/j.ejps.2012.02.014. Epub 2012 Feb 28.

PMID:
22394605
12.

The eighth and ninth transmembrane domains in organic anion transporting polypeptide 1B1 affect the transport kinetics of estrone-3-sulfate and estradiol-17beta-D-glucuronide.

Miyagawa M, Maeda K, Aoyama A, Sugiyama Y.

J Pharmacol Exp Ther. 2009 May;329(2):551-7. doi: 10.1124/jpet.108.148411. Epub 2009 Feb 24.

13.

Preclinical Mouse Models To Study Human OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions in Vivo.

Durmus S, Lozano-Mena G, van Esch A, Wagenaar E, van Tellingen O, Schinkel AH.

Mol Pharm. 2015 Dec 7;12(12):4259-69. doi: 10.1021/acs.molpharmaceut.5b00453. Epub 2015 Oct 29.

PMID:
26474710
14.

Generation of Bayesian prediction models for OATP-mediated drug-drug interactions based on inhibition screen of OATP1B1, OATP1B1∗15 and OATP1B3.

van de Steeg E, Venhorst J, Jansen HT, Nooijen IH, DeGroot J, Wortelboer HM, Vlaming ML.

Eur J Pharm Sci. 2015 Apr 5;70:29-36. doi: 10.1016/j.ejps.2015.01.004. Epub 2015 Jan 17.

PMID:
25603031
15.

Involvement of transporters in the hepatic uptake and biliary excretion of valsartan, a selective antagonist of the angiotensin II AT1-receptor, in humans.

Yamashiro W, Maeda K, Hirouchi M, Adachi Y, Hu Z, Sugiyama Y.

Drug Metab Dispos. 2006 Jul;34(7):1247-54. Epub 2006 Apr 19.

16.

Investigation of the impact of substrate selection on in vitro organic anion transporting polypeptide 1B1 inhibition profiles for the prediction of drug-drug interactions.

Izumi S, Nozaki Y, Maeda K, Komori T, Takenaka O, Kusuhara H, Sugiyama Y.

Drug Metab Dispos. 2015 Feb;43(2):235-47. doi: 10.1124/dmd.114.059105. Epub 2014 Nov 20.

17.

Contribution of OATP (organic anion-transporting polypeptide) family transporters to the hepatic uptake of fexofenadine in humans.

Shimizu M, Fuse K, Okudaira K, Nishigaki R, Maeda K, Kusuhara H, Sugiyama Y.

Drug Metab Dispos. 2005 Oct;33(10):1477-81. Epub 2005 Jul 13.

18.

Drug-drug interaction between pitavastatin and various drugs via OATP1B1.

Hirano M, Maeda K, Shitara Y, Sugiyama Y.

Drug Metab Dispos. 2006 Jul;34(7):1229-36. Epub 2006 Apr 4.

19.

Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the hepatic uptake of pitavastatin in humans.

Hirano M, Maeda K, Shitara Y, Sugiyama Y.

J Pharmacol Exp Ther. 2004 Oct;311(1):139-46. Epub 2004 May 24.

20.

Establishment of a set of double transfectants coexpressing organic anion transporting polypeptide 1B3 and hepatic efflux transporters for the characterization of the hepatobiliary transport of telmisartan acylglucuronide.

Ishiguro N, Maeda K, Saito A, Kishimoto W, Matsushima S, Ebner T, Roth W, Igarashi T, Sugiyama Y.

Drug Metab Dispos. 2008 Apr;36(4):796-805. doi: 10.1124/dmd.107.018903. Epub 2008 Jan 7.

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