Similar articles for PMID: 22220815

Year	Number of Results
2002	1
2003	3
2004	12
2005	12
2006	12
2007	5
2008	10
2009	12
2010	9
2011	12
2012	14
2013	11
2014	10
2015	3
2016	2
2017	2
2019	1
2020	1
2021	1
2024	0

1

Synthesis of new 4,5-dihydrofuranoindoles and their evaluation as HCV NS5B polymerase inhibitors.

Velázquez F, Venkatraman S, Lesburg CA, Duca J, Rosenblum SB, Kozlowski JA, Njoroge FG. Velázquez F, et al. Org Lett. 2012 Jan 20;14(2):556-9. doi: 10.1021/ol203177g. Epub 2012 Jan 5. Org Lett. 2012. PMID: 22220815

2

The discovery and structure-activity relationships of pyrano[3,4-b]indole-based inhibitors of hepatitis C virus NS5B polymerase.

Jackson RW, LaPorte MG, Herbertz T, Draper TL, Gaboury JA, Rippin SR, Patel R, Chunduru SK, Benetatos CA, Young DC, Burns CJ, Condon SM. Jackson RW, et al. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3227-31. doi: 10.1016/j.bmcl.2011.04.052. Epub 2011 Apr 21. Bioorg Med Chem Lett. 2011. PMID: 21550237

3

Parallel synthesis of 5-cyano-6-aryl-2-thiouracil derivatives as inhibitors for hepatitis C viral NS5B RNA-dependent RNA polymerase.

Ding Y, Girardet JL, Smith KL, Larson G, Prigaro B, Wu JZ, Yao N. Ding Y, et al. Bioorg Chem. 2006 Feb;34(1):26-38. doi: 10.1016/j.bioorg.2005.10.001. Epub 2005 Dec 19. Bioorg Chem. 2006. PMID: 16360193

4

Development and preliminary optimization of indole-N-acetamide inhibitors of hepatitis C virus NS5B polymerase.

Harper S, Pacini B, Avolio S, Di Filippo M, Migliaccio G, Laufer R, De Francesco R, Rowley M, Narjes F. Harper S, et al. J Med Chem. 2005 Mar 10;48(5):1314-7. doi: 10.1021/jm049122i. J Med Chem. 2005. PMID: 15743173

5

Further SAR studies on novel small molecule inhibitors of the hepatitis C (HCV) NS5B polymerase.

Reddy TJ, Chan L, Turcotte N, Proulx M, Pereira OZ, Das SK, Siddiqui A, Wang W, Poisson C, Yannopoulos CG, Bilimoria D, L'Heureux L, Alaoui HM, Nguyen-Ba N. Reddy TJ, et al. Bioorg Med Chem Lett. 2003 Oct 6;13(19):3341-4. doi: 10.1016/s0960-894x(03)00670-x. Bioorg Med Chem Lett. 2003. PMID: 12951122

6

Preparation and biological evaluation of 1'-cyano-2'-C-methyl pyrimidine nucleosides as HCV NS5B polymerase inhibitors.

Mish MR, Cho A, Kirschberg T, Xu J, Zonte CS, Fenaux M, Park Y, Babusis D, Feng JY, Ray AS, Kim CU. Mish MR, et al. Bioorg Med Chem Lett. 2014 Jul 15;24(14):3092-5. doi: 10.1016/j.bmcl.2014.05.015. Epub 2014 May 22. Bioorg Med Chem Lett. 2014. PMID: 24907145

7

The discovery of pyrano[3,4-b]indole-based allosteric inhibitors of HCV NS5B polymerase with in vivo activity.

Laporte MG, Jackson RW, Draper TL, Gaboury JA, Galie K, Herbertz T, Hussey AR, Rippin SR, Benetatos CA, Chunduru SK, Christensen JS, Coburn GA, Rizzo CJ, Rhodes G, O'Connell J, Howe AY, Mansour TS, Collett MS, Pevear DC, Young DC, Gao T, Tyrrell DL, Kneteman NM, Burns CJ, Condon SM. Laporte MG, et al. ChemMedChem. 2008 Oct;3(10):1508-15. doi: 10.1002/cmdc.200800168. ChemMedChem. 2008. PMID: 18729128 No abstract available.

8

Current perspective of HCV NS5B inhibitors: a review.

Patil VM, Gupta SP, Samanta S, Masand N. Patil VM, et al. Curr Med Chem. 2011;18(36):5564-97. doi: 10.2174/092986711798347234. Curr Med Chem. 2011. PMID: 22172066 Review.

9

Potent inhibitors of subgenomic hepatitis C virus RNA replication through optimization of indole-N-acetamide allosteric inhibitors of the viral NS5B polymerase.

Harper S, Avolio S, Pacini B, Di Filippo M, Altamura S, Tomei L, Paonessa G, Di Marco S, Carfi A, Giuliano C, Padron J, Bonelli F, Migliaccio G, De Francesco R, Laufer R, Rowley M, Narjes F. Harper S, et al. J Med Chem. 2005 Jul 14;48(14):4547-57. doi: 10.1021/jm050056+. J Med Chem. 2005. PMID: 15999993

10

Discovery of a potent boronic acid derived inhibitor of the HCV RNA-dependent RNA polymerase.

Maynard A, Crosby RM, Ellis B, Hamatake R, Hong Z, Johns BA, Kahler KM, Koble C, Leivers A, Leivers MR, Mathis A, Peat AJ, Pouliot JJ, Roberts CD, Samano V, Schmidt RM, Smith GK, Spaltenstein A, Stewart EL, Thommes P, Turner EM, Voitenleitner C, Walker JT, Waitt G, Weatherhead J, Weaver K, Williams S, Wright L, Xiong ZZ, Haigh D, Shotwell JB. Maynard A, et al. J Med Chem. 2014 Mar 13;57(5):1902-13. doi: 10.1021/jm400317w. Epub 2013 May 29. J Med Chem. 2014. PMID: 23672667

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