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Items: 1 to 20 of 109

1.

Differential localization of sphingomyelin synthase isoforms in neurons regulates sphingomyelin cluster formation.

Kidani Y, Ohshima K, Sakai H, Kohno T, Baba A, Hattori M.

Biochem Biophys Res Commun. 2012 Jan 20;417(3):1014-7. doi: 10.1016/j.bbrc.2011.12.079. Epub 2011 Dec 22.

PMID:
22209789
2.

Inhibition of sphingomyelin synthase (SMS) affects intracellular sphingomyelin accumulation and plasma membrane lipid organization.

Li Z, Hailemariam TK, Zhou H, Li Y, Duckworth DC, Peake DA, Zhang Y, Kuo MS, Cao G, Jiang XC.

Biochim Biophys Acta. 2007 Sep;1771(9):1186-94. Epub 2007 Jun 6.

3.

SMS overexpression and knockdown: impact on cellular sphingomyelin and diacylglycerol metabolism, and cell apoptosis.

Ding T, Li Z, Hailemariam T, Mukherjee S, Maxfield FR, Wu MP, Jiang XC.

J Lipid Res. 2008 Feb;49(2):376-85. Epub 2007 Nov 2.

4.

Both sphingomyelin synthases SMS1 and SMS2 are required for sphingomyelin homeostasis and growth in human HeLa cells.

Tafesse FG, Huitema K, Hermansson M, van der Poel S, van den Dikkenberg J, Uphoff A, Somerharju P, Holthuis JC.

J Biol Chem. 2007 Jun 15;282(24):17537-47. Epub 2007 Apr 22.

5.

Adenovirus-mediated overexpression of sphingomyelin synthases 1 and 2 increases the atherogenic potential in mice.

Dong J, Liu J, Lou B, Li Z, Ye X, Wu M, Jiang XC.

J Lipid Res. 2006 Jun;47(6):1307-14. Epub 2006 Feb 28.

6.

Sphingomyelin synthase 2 is one of the determinants for plasma and liver sphingomyelin levels in mice.

Liu J, Zhang H, Li Z, Hailemariam TK, Chakraborty M, Jiang K, Qiu D, Bui HH, Peake DA, Kuo MS, Wadgaonkar R, Cao G, Jiang XC.

Arterioscler Thromb Vasc Biol. 2009 Jun;29(6):850-6. doi: 10.1161/ATVBAHA.109.185223. Epub 2009 Mar 12.

7.

Development of a quantitative biochemical and cellular sphingomyelin synthase assay using mass spectrometry.

Chen Y, Yurek DA, Yu L, Wang H, Ehsani ME, Qian YW, Konrad RJ, Jiang XC, Kuo MS, Cao G, Wang J.

Anal Biochem. 2013 Jul 1;438(1):61-6. doi: 10.1016/j.ab.2013.03.016. Epub 2013 Mar 25.

PMID:
23535273
8.

Expression cloning of a human cDNA restoring sphingomyelin synthesis and cell growth in sphingomyelin synthase-defective lymphoid cells.

Yamaoka S, Miyaji M, Kitano T, Umehara H, Okazaki T.

J Biol Chem. 2004 Apr 30;279(18):18688-93. Epub 2004 Feb 19.

9.

Dynamic modification of sphingomyelin in lipid microdomains controls development of obesity, fatty liver, and type 2 diabetes.

Mitsutake S, Zama K, Yokota H, Yoshida T, Tanaka M, Mitsui M, Ikawa M, Okabe M, Tanaka Y, Yamashita T, Takemoto H, Okazaki T, Watanabe K, Igarashi Y.

J Biol Chem. 2011 Aug 12;286(32):28544-55. doi: 10.1074/jbc.M111.255646. Epub 2011 Jun 13.

10.

Role of membrane sphingomyelin and ceramide in platform formation for Fas-mediated apoptosis.

Miyaji M, Jin ZX, Yamaoka S, Amakawa R, Fukuhara S, Sato SB, Kobayashi T, Domae N, Mimori T, Bloom ET, Okazaki T, Umehara H.

J Exp Med. 2005 Jul 18;202(2):249-59. Epub 2005 Jul 11.

11.

Sphingomyelin synthase SMS2 displays dual activity as ceramide phosphoethanolamine synthase.

Ternes P, Brouwers JF, van den Dikkenberg J, Holthuis JC.

J Lipid Res. 2009 Nov;50(11):2270-7. doi: 10.1194/jlr.M900230-JLR200. Epub 2009 May 19.

12.

Subcellular localization of sphingomyelin revealed by two toxin-based probes in mammalian cells.

Yachi R, Uchida Y, Balakrishna BH, Anderluh G, Kobayashi T, Taguchi T, Arai H.

Genes Cells. 2012 Aug;17(8):720-7. doi: 10.1111/j.1365-2443.2012.01621.x. Epub 2012 Jul 2.

13.

Impaired TCR signaling through dysfunction of lipid rafts in sphingomyelin synthase 1 (SMS1)-knockdown T cells.

Jin ZX, Huang CR, Dong L, Goda S, Kawanami T, Sawaki T, Sakai T, Tong XP, Masaki Y, Fukushima T, Tanaka M, Mimori T, Tojo H, Bloom ET, Okazaki T, Umehara H.

Int Immunol. 2008 Nov;20(11):1427-37. doi: 10.1093/intimm/dxn100. Epub 2008 Sep 26.

PMID:
18820264
14.

All members in the sphingomyelin synthase gene family have ceramide phosphoethanolamine synthase activity.

Ding T, Kabir I, Li Y, Lou C, Yazdanyar A, Xu J, Dong J, Zhou H, Park T, Boutjdir M, Li Z, Jiang XC.

J Lipid Res. 2015 Mar;56(3):537-45. doi: 10.1194/jlr.M054627. Epub 2015 Jan 20.

16.

Identification of a family of animal sphingomyelin synthases.

Huitema K, van den Dikkenberg J, Brouwers JF, Holthuis JC.

EMBO J. 2004 Jan 14;23(1):33-44. Epub 2003 Dec 18.

17.

Sphingomyelin synthase 2 deficiency attenuates NFkappaB activation.

Hailemariam TK, Huan C, Liu J, Li Z, Roman C, Kalbfeisch M, Bui HH, Peake DA, Kuo MS, Cao G, Wadgaonkar R, Jiang XC.

Arterioscler Thromb Vasc Biol. 2008 Aug;28(8):1519-26. doi: 10.1161/ATVBAHA.108.168682. Epub 2008 Jun 19.

18.

A sensitive cell-based method to screen for selective inhibitors of SMS1 or SMS2 using HPLC and a fluorescent substrate.

Zama K, Mitsutake S, Watanabe K, Okazaki T, Igarashi Y.

Chem Phys Lipids. 2012 Oct;165(7):760-8. doi: 10.1016/j.chemphyslip.2012.09.003. Epub 2012 Oct 11.

PMID:
23063490
19.

The domain responsible for sphingomyelin synthase (SMS) activity.

Yeang C, Varshney S, Wang R, Zhang Y, Ye D, Jiang XC.

Biochim Biophys Acta. 2008 Oct;1781(10):610-7. doi: 10.1016/j.bbalip.2008.07.002. Epub 2008 Jul 23.

20.

Sphingomyelin synthase 2 is palmitoylated at the COOH-terminal tail, which is involved in its localization in plasma membranes.

Tani M, Kuge O.

Biochem Biophys Res Commun. 2009 Apr 10;381(3):328-32. doi: 10.1016/j.bbrc.2009.02.063. Epub 2009 Feb 20.

PMID:
19233134

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