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[The role and mechanism of high expression of cyclin B2 in MEN1 insulinoma].

Wu T, Huang XH.

Sheng Li Xue Bao. 2011 Dec 25;63(6):555-64. Chinese.


Regulation of cyclin B2 expression and cell cycle G2/m transition by menin.

Wu T, Zhang X, Huang X, Yang Y, Hua X.

J Biol Chem. 2010 Jun 11;285(24):18291-300. doi: 10.1074/jbc.M110.106575. Epub 2010 Apr 19.


Gene expression profiling in insulinomas of Men1 beta-cell mutant mice reveals early genetic and epigenetic events involved in pancreatic beta-cell tumorigenesis.

Fontanière S, Tost J, Wierinckx A, Lachuer J, Lu J, Hussein N, Busato F, Gut I, Wang ZQ, Zhang CX.

Endocr Relat Cancer. 2006 Dec;13(4):1223-36.


Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c.

Karnik SK, Hughes CM, Gu X, Rozenblatt-Rosen O, McLean GW, Xiong Y, Meyerson M, Kim SK.

Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14659-64. Epub 2005 Sep 29.


Mechanisms of disease: multiple endocrine neoplasia type 1-relation to chromatin modifications and transcription regulation.

Dreijerink KM, Höppener JW, Timmers HM, Lips CJ.

Nat Clin Pract Endocrinol Metab. 2006 Oct;2(10):562-70. Review.


Analysis of p27(Kip1) expression in insulinomas developed in pancreatic beta-cell specific Men1 mutant mice.

Fontanière S, Casse H, Bertolino P, Zhang CX.

Fam Cancer. 2006;5(1):49-54.


Multiple endocrine neoplasia type 1: a chromatin writer's block.

Dreijerink KM, Lips CJ, Timmers HT.

J Intern Med. 2009 Jul;266(1):53-9. doi: 10.1111/j.1365-2796.2009.02115.x. Review.


The multiple endocrine neoplasia type 1 gene product, menin, inhibits insulin production in rat insulinoma cells.

Sayo Y, Murao K, Imachi H, Cao WM, Sato M, Dobashi H, Wong NC, Ishida T.

Endocrinology. 2002 Jun;143(6):2437-40.


Menin promotes the Wnt signaling pathway in pancreatic endocrine cells.

Chen G, A J, Wang M, Farley S, Lee LY, Lee LC, Sawicki MP.

Mol Cancer Res. 2008 Dec;6(12):1894-907. doi: 10.1158/1541-7786.MCR-07-2206.


The Cell Death Inhibitor ARC Is Induced in a Tissue-Specific Manner by Deletion of the Tumor Suppressor Gene Men1, but Not Required for Tumor Development and Growth.

McKimpson WM, Yuan Z, Zheng M, Crabtree JS, Libutti SK, Kitsis RN.

PLoS One. 2015 Dec 28;10(12):e0145792. doi: 10.1371/journal.pone.0145792. eCollection 2015.


The role of tumor suppressor menin in IL-6 regulation in mouse islet tumor cells.

Song TY, Lim J, Kim B, Han JW, Youn HD, Cho EJ.

Biochem Biophys Res Commun. 2014 Aug 22;451(2):308-13. doi: 10.1016/j.bbrc.2014.07.113. Epub 2014 Aug 1.


MEN1 in pancreatic endocrine tumors: analysis of gene and protein status in 169 sporadic neoplasms reveals alterations in the vast majority of cases.

Corbo V, Dalai I, Scardoni M, Barbi S, Beghelli S, Bersani S, Albarello L, Doglioni C, Schott C, Capelli P, Chilosi M, Boninsegna L, Becker KF, Falconi M, Scarpa A.

Endocr Relat Cancer. 2010 Aug 16;17(3):771-83. doi: 10.1677/ERC-10-0028. Print 2010 Sep.


Menin expression is regulated by transforming growth factor beta signaling in leukemia cells.

Zhang H, Liu ZG, Hua XX.

Chin Med J (Engl). 2011 May;124(10):1556-62.


Conditional inactivation of the MEN1 gene leads to pancreatic and pituitary tumorigenesis but does not affect normal development of these tissues.

Biondi CA, Gartside MG, Waring P, Loffler KA, Stark MS, Magnuson MA, Kay GF, Hayward NK.

Mol Cell Biol. 2004 Apr;24(8):3125-31.


MEN1 missense mutations impair sensitization to apoptosis induced by wild-type menin in endocrine pancreatic tumor cells.

Bazzi W, Renon M, Vercherat C, Hamze Z, Lacheretz-Bernigaud A, Wang H, Blanc M, Roche C, Calender A, Chayvialle JA, Scoazec JY, Cordier-Bussat M.

Gastroenterology. 2008 Nov;135(5):1698-1709.e2. doi: 10.1053/j.gastro.2008.07.031. Epub 2008 Jul 31.


Menin epigenetically represses Hedgehog signaling in MEN1 tumor syndrome.

Gurung B, Feng Z, Iwamoto DV, Thiel A, Jin G, Fan CM, Ng JM, Curran T, Hua X.

Cancer Res. 2013 Apr 15;73(8):2650-8. doi: 10.1158/0008-5472.CAN-12-3158. Epub 2013 Apr 11.


Mutation of the MENIN gene in sporadic pancreatic endocrine tumors.

Wang EH, Ebrahimi SA, Wu AY, Kashefi C, Passaro E Jr, Sawicki MP.

Cancer Res. 1998 Oct 1;58(19):4417-20.


The gene for multiple endocrine neoplasia type 1: recent findings.

Marx SJ, Agarwal SK, Heppner C, Kim YS, Kester MB, Goldsmith PK, Skarulis MC, Spiegel AM, Burns AL, Debelenko LV, Zhuang Z, Lubensky IA, Liotta LA, Emmert-Buck MR, Guru SC, Manickam P, Crabtree JS, Collins FS, Chandrasekharappa SC.

Bone. 1999 Jul;25(1):119-22. Review.


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