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Items: 1 to 20 of 134

1.

Molecular signatures associated with Mx1-mediated resistance to highly pathogenic influenza virus infection: mechanisms of survival.

Cilloniz C, Pantin-Jackwood MJ, Ni C, Carter VS, Korth MJ, Swayne DE, Tumpey TM, Katze MG.

J Virol. 2012 Mar;86(5):2437-46. doi: 10.1128/JVI.06156-11. Epub 2011 Dec 21.

2.

Protection from Severe Influenza Virus Infections in Mice Carrying the Mx1 Influenza Virus Resistance Gene Strongly Depends on Genetic Background.

Shin DL, Hatesuer B, Bergmann S, Nedelko T, Schughart K.

J Virol. 2015 Oct;89(19):9998-10009. doi: 10.1128/JVI.01305-15. Epub 2015 Jul 22.

3.

The Mx1 gene protects mice against the pandemic 1918 and highly lethal human H5N1 influenza viruses.

Tumpey TM, Szretter KJ, Van Hoeven N, Katz JM, Kochs G, Haller O, García-Sastre A, Staeheli P.

J Virol. 2007 Oct;81(19):10818-21. Epub 2007 Jul 25.

4.

Early regulation of viral infection reduces inflammation and rescues mx-positive mice from lethal avian influenza infection.

Song MS, Cho YH, Park SJ, Pascua PN, Baek YH, Kwon HI, Lee OJ, Kong BW, Kim H, Shin EC, Kim CJ, Choi YK.

Am J Pathol. 2013 Apr;182(4):1308-21. doi: 10.1016/j.ajpath.2012.12.022. Epub 2013 Feb 8.

PMID:
23395090
5.

Mx1 gene protects mice against the highly lethal human H5N1 influenza virus.

Salomon R, Staeheli P, Kochs G, Yen HL, Franks J, Rehg JE, Webster RG, Hoffmann E.

Cell Cycle. 2007 Oct 1;6(19):2417-21. Epub 2007 Jul 22.

PMID:
17700072
6.

Replication fitness determines high virulence of influenza A virus in mice carrying functional Mx1 resistance gene.

Grimm D, Staeheli P, Hufbauer M, Koerner I, Martínez-Sobrido L, Solórzano A, García-Sastre A, Haller O, Kochs G.

Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6806-11. Epub 2007 Apr 10.

7.

Lethal synergism of 2009 pandemic H1N1 influenza virus and Streptococcus pneumoniae coinfection is associated with loss of murine lung repair responses.

Kash JC, Walters KA, Davis AS, Sandouk A, Schwartzman LM, Jagger BW, Chertow DS, Li Q, Kuestner RE, Ozinsky A, Taubenberger JK.

MBio. 2011 Sep 20;2(5). pii: e00172-11. doi: 10.1128/mBio.00172-11. Print 2011.

8.

Influenza A virus strains differ in sensitivity to the antiviral action of Mx-GTPase.

Dittmann J, Stertz S, Grimm D, Steel J, García-Sastre A, Haller O, Kochs G.

J Virol. 2008 Apr;82(7):3624-31. doi: 10.1128/JVI.01753-07. Epub 2008 Jan 16.

9.

Influenza Virus Susceptibility of Wild-Derived CAST/EiJ Mice Results from Two Amino Acid Changes in the MX1 Restriction Factor.

Nürnberger C, Zimmermann V, Gerhardt M, Staeheli P.

J Virol. 2016 Nov 14;90(23):10682-10692. Print 2016 Dec 1.

10.

Association of Mx1 Asn631 variant alleles with reductions in morbidity, early mortality, viral shedding, and cytokine responses in chickens infected with a highly pathogenic avian influenza virus.

Ewald SJ, Kapczynski DR, Livant EJ, Suarez DL, Ralph J, McLeod S, Miller C.

Immunogenetics. 2011 Jun;63(6):363-75. doi: 10.1007/s00251-010-0509-1. Epub 2011 Feb 1.

PMID:
21286706
11.

Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus.

Kobasa D, Jones SM, Shinya K, Kash JC, Copps J, Ebihara H, Hatta Y, Kim JH, Halfmann P, Hatta M, Feldmann F, Alimonti JB, Fernando L, Li Y, Katze MG, Feldmann H, Kawaoka Y.

Nature. 2007 Jan 18;445(7125):319-23.

PMID:
17230189
12.

Type I interferon limits influenza virus-induced acute lung injury by regulation of excessive inflammation in mice.

Arimori Y, Nakamura R, Yamada H, Shibata K, Maeda N, Kase T, Yoshikai Y.

Antiviral Res. 2013 Sep;99(3):230-7. doi: 10.1016/j.antiviral.2013.05.007. Epub 2013 May 28.

PMID:
23721943
13.

Interferon-inducible Mx gene expression in cotton rats: cloning, characterization, and expression during influenza viral infection.

Pletneva LM, Haller O, Porter DD, Prince GA, Blanco JC.

J Interferon Cytokine Res. 2006 Dec;26(12):914-21.

PMID:
17238834
14.

Age-related sensitivity and pathological differences in infections by 2009 pandemic influenza A (H1N1) virus.

Sun S, Zhao G, Xiao W, Hu J, Guo Y, Yu H, Wu X, Tan Y, Zhou Y.

Virol J. 2011 Feb 8;8:52. doi: 10.1186/1743-422X-8-52.

16.

The viral nucleoprotein determines Mx sensitivity of influenza A viruses.

Zimmermann P, Mänz B, Haller O, Schwemmle M, Kochs G.

J Virol. 2011 Aug;85(16):8133-40. doi: 10.1128/JVI.00712-11. Epub 2011 Jun 15.

17.

Mx1 but not MxA confers resistance against tick-borne Dhori virus in mice.

Thimme R, Frese M, Kochs G, Haller O.

Virology. 1995 Aug 1;211(1):296-301.

18.

Interferon-inducible protein Mx1 inhibits influenza virus by interfering with functional viral ribonucleoprotein complex assembly.

Verhelst J, Parthoens E, Schepens B, Fiers W, Saelens X.

J Virol. 2012 Dec;86(24):13445-55. doi: 10.1128/JVI.01682-12. Epub 2012 Sep 26.

19.

Activity of ultra-low doses of antibodies to gamma-interferon against lethal influenza A(H1N1)2009 virus infection in mice.

Tarasov SA, Zarubaev VV, Gorbunov EA, Sergeeva SA, Epstein OI.

Antiviral Res. 2012 Feb;93(2):219-24. doi: 10.1016/j.antiviral.2011.11.018. Epub 2011 Dec 8.

PMID:
22178245
20.

Functional Comparison of Mx1 from Two Different Mouse Species Reveals the Involvement of Loop L4 in the Antiviral Activity against Influenza A Viruses.

Verhelst J, Spitaels J, Nürnberger C, De Vlieger D, Ysenbaert T, Staeheli P, Fiers W, Saelens X.

J Virol. 2015 Nov;89(21):10879-90. doi: 10.1128/JVI.01744-15. Epub 2015 Aug 19.

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