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Items: 1 to 20 of 113

1.
3.

Capsaicin is a novel blocker of constitutive and interleukin-6-inducible STAT3 activation.

Bhutani M, Pathak AK, Nair AS, Kunnumakkara AB, Guha S, Sethi G, Aggarwal BB.

Clin Cancer Res. 2007 May 15;13(10):3024-32.

4.

Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis.

Badr G, Lefevre EA, Mohany M.

PLoS One. 2011;6(9):e23741. doi: 10.1371/journal.pone.0023741. Epub 2011 Sep 1.

5.

Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2- and Src‑mediated phosphorylation of EGF receptor tyrosine kinase.

Kundu J, Choi BY, Jeong CH, Kundu JK, Chun KS.

Oncol Rep. 2014 Aug;32(2):821-8. doi: 10.3892/or.2014.3223. Epub 2014 May 29.

PMID:
24890449
6.

Thymoquinone inhibits proliferation in gastric cancer via the STAT3 pathway in vivo and in vitro.

Zhu WQ, Wang J, Guo XF, Liu Z, Dong WG.

World J Gastroenterol. 2016 Apr 28;22(16):4149-59. doi: 10.3748/wjg.v22.i16.4149.

7.

Oleanane triterpenoid CDDO-Me induces apoptosis in multidrug resistant osteosarcoma cells through inhibition of Stat3 pathway.

Ryu K, Susa M, Choy E, Yang C, Hornicek FJ, Mankin HJ, Duan Z.

BMC Cancer. 2010 May 10;10:187. doi: 10.1186/1471-2407-10-187.

8.

Inhibitory effect of baicalein on IL-6-mediated signaling cascades in human myeloma cells.

Liu S, Ma Z, Cai H, Li Q, Rong W, Kawano M.

Eur J Haematol. 2010 Feb 1;84(2):137-44. doi: 10.1111/j.1600-0609.2009.01365.x. Epub 2009 Oct 28.

PMID:
19878271
9.

[Effects of siltuximab on the interleukin-6/Stat3 signaling pathway in ovarian cancer].

Guo YQ, Lu P, Duan ZF, Zhang Z.

Zhonghua Fu Chan Ke Za Zhi. 2010 Nov;45(11):854-9. Chinese.

PMID:
21211286
10.

Tanshinone IIA inhibits constitutive STAT3 activation, suppresses proliferation, and induces apoptosis in rat C6 glioma cells.

Tang C, Xue HL, Huang HB, Wang XG.

Neurosci Lett. 2010 Feb 12;470(2):126-9. doi: 10.1016/j.neulet.2009.12.069. Epub 2010 Jan 5.

PMID:
20045721
11.

STAT3 mRNA and protein expression in colorectal cancer: effects on STAT3-inducible targets linked to cell survival and proliferation.

Lassmann S, Schuster I, Walch A, Göbel H, Jütting U, Makowiec F, Hopt U, Werner M.

J Clin Pathol. 2007 Feb;60(2):173-9.

12.

A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells.

Lin L, Hutzen B, Li PK, Ball S, Zuo M, DeAngelis S, Foust E, Sobo M, Friedman L, Bhasin D, Cen L, Li C, Lin J.

Neoplasia. 2010 Jan;12(1):39-50.

13.

Thymoquinone from Nigella sativa was more potent than cisplatin in eliminating of SiHa cells via apoptosis with down-regulation of Bcl-2 protein.

Ng WK, Yazan LS, Ismail M.

Toxicol In Vitro. 2011 Oct;25(7):1392-8. doi: 10.1016/j.tiv.2011.04.030. Epub 2011 May 15.

PMID:
21609759
14.

Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein.

Kotha A, Sekharam M, Cilenti L, Siddiquee K, Khaled A, Zervos AS, Carter B, Turkson J, Jove R.

Mol Cancer Ther. 2006 Mar;5(3):621-9.

15.

Anticancer activity of thymoquinone in breast cancer cells: possible involvement of PPAR-γ pathway.

Woo CC, Loo SY, Gee V, Yap CW, Sethi G, Kumar AP, Tan KH.

Biochem Pharmacol. 2011 Sep 1;82(5):464-75. doi: 10.1016/j.bcp.2011.05.030. Epub 2011 Jun 14.

PMID:
21679698
16.

Prokineticin-1/endocrine gland-derived vascular endothelial growth factor is a survival factor for human multiple myeloma cells.

Li QF, Zhu HY, Yang YF, Liu J, Xiao FJ, Zhang QW, Wu CT, Wang H, Wang LS.

Leuk Lymphoma. 2010 Oct;51(10):1902-12. doi: 10.3109/10428194.2010.512963.

PMID:
20795791
17.

Patrinia scabiosaefolia extract suppresses proliferation and promotes apoptosis by inhibiting the STAT3 pathway in human multiple myeloma cells.

Peng J, Chen Y, Lin J, Zhuang Q, Xu W, Hong Z, Sferra TJ.

Mol Med Rep. 2011 Mar-Apr;4(2):313-8. doi: 10.3892/mmr.2011.413. Epub 2011 Jan 3.

PMID:
21468570
18.

Thymoquinone up-regulates PTEN expression and induces apoptosis in doxorubicin-resistant human breast cancer cells.

Arafa el-SA, Zhu Q, Shah ZI, Wani G, Barakat BM, Racoma I, El-Mahdy MA, Wani AA.

Mutat Res. 2011 Jan 10;706(1-2):28-35. doi: 10.1016/j.mrfmmm.2010.10.007. Epub 2010 Oct 30.

19.

Kahweol blocks STAT3 phosphorylation and induces apoptosis in human lung adenocarcinoma A549 cells.

Kim HG, Hwang YP, Jeong HG.

Toxicol Lett. 2009 May 22;187(1):28-34. doi: 10.1016/j.toxlet.2009.01.022. Epub 2009 Jan 24.

PMID:
19429240
20.

Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism.

Gali-Muhtasib H, Diab-Assaf M, Boltze C, Al-Hmaira J, Hartig R, Roessner A, Schneider-Stock R.

Int J Oncol. 2004 Oct;25(4):857-66.

PMID:
15375533

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