Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 89


The human cytomegalovirus UL11 protein interacts with the receptor tyrosine phosphatase CD45, resulting in functional paralysis of T cells.

Gabaev I, Steinbrück L, Pokoyski C, Pich A, Stanton RJ, Schwinzer R, Schulz TF, Jacobs R, Messerle M, Kay-Fedorov PC.

PLoS Pathog. 2011 Dec;7(12):e1002432. doi: 10.1371/journal.ppat.1002432. Epub 2011 Dec 8.


The human cytomegalovirus glycoprotein pUL11 acts via CD45 to induce T cell IL-10 secretion.

Zischke J, Mamareli P, Pokoyski C, Gabaev I, Buyny S, Jacobs R, Falk CS, Lochner M, Sparwasser T, Schulz TF, Kay-Fedorov PC.

PLoS Pathog. 2017 Jun 19;13(6):e1006454. doi: 10.1371/journal.ppat.1006454. eCollection 2017 Jun.


Expression of the human cytomegalovirus UL11 glycoprotein in viral infection and evaluation of its effect on virus-specific CD8 T cells.

Gabaev I, Elbasani E, Ameres S, Steinbrück L, Stanton R, Döring M, Lenac Rovis T, Kalinke U, Jonjic S, Moosmann A, Messerle M.

J Virol. 2014 Dec;88(24):14326-39. doi: 10.1128/JVI.01691-14. Epub 2014 Oct 1.


CD45-associated kinase activity requires lck but not T cell receptor expression in the Jurkat T cell line.

Koretzky GA, Kohmetscher M, Ross S.

J Biol Chem. 1993 Apr 25;268(12):8958-64.


CD45 and RPTPalpha display different protein tyrosine phosphatase activities in T lymphocytes.

Ng DH, Jabali MD, Maiti A, Borodchak P, Harder KW, Brocker T, Malissen B, Jirik FR, Johnson P.

Biochem J. 1997 Nov 1;327 ( Pt 3):867-76.


CD45 down-regulates Lck-mediated CD44 signaling and modulates actin rearrangement in T cells.

Wong NK, Lai JC, Birkenhead D, Shaw AS, Johnson P.

J Immunol. 2008 Nov 15;181(10):7033-43.


The association between CD45 and lck does not require CD4 or CD8 and is independent of T cell receptor stimulation.

Ross SE, Schraven B, Goldman FD, Crabtree J, Koretzky GA.

Biochem Biophys Res Commun. 1994 Jan 14;198(1):88-96.


Interaction between CD45-AP and protein-tyrosine kinases involved in T cell receptor signaling.

Motoya S, Kitamura K, Matsuda A, Maizel AL, Yamamoto H, Takeda A.

J Biol Chem. 1999 Jan 15;274(3):1407-14.


Aberrant TCR-mediated signaling in CD45-null thymocytes involves dysfunctional regulation of Lck, Fyn, TCR-zeta, and ZAP-70.

Stone JD, Conroy LA, Byth KF, Hederer RA, Howlett S, Takemoto Y, Holmes N, Alexander DR.

J Immunol. 1997 Jun 15;158(12):5773-82.


Targeting of CD45 protein tyrosine phosphatase activity to lipid microdomains on the T cell surface inhibits TCR signaling.

He X, Woodford-Thomas TA, Johnson KG, Shah DD, Thomas ML.

Eur J Immunol. 2002 Sep;32(9):2578-87.


CD44-initiated cell spreading induces Pyk2 phosphorylation, is mediated by Src family kinases, and is negatively regulated by CD45.

Li R, Wong N, Jabali MD, Johnson P.

J Biol Chem. 2001 Aug 3;276(31):28767-73. Epub 2001 May 21.


Stimulatory effects of the protein tyrosine phosphatase inhibitor, pervanadate, on T-cell activation events.

Secrist JP, Burns LA, Karnitz L, Koretzky GA, Abraham RT.

J Biol Chem. 1993 Mar 15;268(8):5886-93.


Interactions of CD45-associated protein with the antigen receptor signaling machinery in T-lymphocytes.

Veillette A, Soussou D, Latour S, Davidson D, Gervais FG.

J Biol Chem. 1999 May 14;274(20):14392-9.


Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase.

Desai DM, Sap J, Schlessinger J, Weiss A.

Cell. 1993 May 7;73(3):541-54.


Supplemental Content

Support Center