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Items: 1 to 20 of 169

1.

A novel role for the NLRC4 inflammasome in mucosal defenses against the fungal pathogen Candida albicans.

Tomalka J, Ganesan S, Azodi E, Patel K, Majmudar P, Hall BA, Fitzgerald KA, Hise AG.

PLoS Pathog. 2011 Dec;7(12):e1002379. doi: 10.1371/journal.ppat.1002379. Epub 2011 Dec 8.

2.

Pathogenic NLRP3 Inflammasome Activity during Candida Infection Is Negatively Regulated by IL-22 via Activation of NLRC4 and IL-1Ra.

Borghi M, De Luca A, Puccetti M, Jaeger M, Mencacci A, Oikonomou V, Pariano M, Garlanda C, Moretti S, Bartoli A, Sobel J, van de Veerdonk FL, Dinarello CA, Netea MG, Romani L.

Cell Host Microbe. 2015 Aug 12;18(2):198-209. doi: 10.1016/j.chom.2015.07.004.

3.

β-arrestin1 is critical for the full activation of NLRP3 and NLRC4 inflammasomes.

Mao K, Chen S, Wang Y, Zeng Y, Ma Y, Hu Y, Zhang H, Sun S, Wu X, Meng G, Pei G, Sun B.

J Immunol. 2015 Feb 15;194(4):1867-73. doi: 10.4049/jimmunol.1401989. Epub 2015 Jan 12.

4.

Inflammasome-dependent pyroptosis and IL-18 protect against Burkholderia pseudomallei lung infection while IL-1β is deleterious.

Ceballos-Olvera I, Sahoo M, Miller MA, Del Barrio L, Re F.

PLoS Pathog. 2011 Dec;7(12):e1002452. doi: 10.1371/journal.ppat.1002452. Epub 2011 Dec 29.

5.

Caspase-8 modulates dectin-1 and complement receptor 3-driven IL-1β production in response to β-glucans and the fungal pathogen, Candida albicans.

Ganesan S, Rathinam VAK, Bossaller L, Army K, Kaiser WJ, Mocarski ES, Dillon CP, Green DR, Mayadas TN, Levitz SM, Hise AG, Silverman N, Fitzgerald KA.

J Immunol. 2014 Sep 1;193(5):2519-2530. doi: 10.4049/jimmunol.1400276. Epub 2014 Jul 25.

6.

An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans.

Hise AG, Tomalka J, Ganesan S, Patel K, Hall BA, Brown GD, Fitzgerald KA.

Cell Host Microbe. 2009 May 8;5(5):487-97. doi: 10.1016/j.chom.2009.05.002.

7.

Chlamydia pneumoniae harness host NLRP3 inflammasome-mediated caspase-1 activation for optimal intracellular growth in murine macrophages.

Itoh R, Murakami I, Chou B, Ishii K, Soejima T, Suzuki T, Hiromatsu K.

Biochem Biophys Res Commun. 2014 Sep 26;452(3):689-94. doi: 10.1016/j.bbrc.2014.08.128. Epub 2014 Sep 1.

PMID:
25193701
8.

Genipin inhibits NLRP3 and NLRC4 inflammasome activation via autophagy suppression.

Yu SX, Du CT, Chen W, Lei QQ, Li N, Qi S, Zhang XJ, Hu GQ, Deng XM, Han WY, Yang YJ.

Sci Rep. 2015 Dec 11;5:17935. doi: 10.1038/srep17935.

9.

Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii.

Gorfu G, Cirelli KM, Melo MB, Mayer-Barber K, Crown D, Koller BH, Masters S, Sher A, Leppla SH, Moayeri M, Saeij JP, Grigg ME.

MBio. 2014 Feb 18;5(1). pii: e01117-13. doi: 10.1128/mBio.01117-13.

10.

Transcriptomic analysis of vulvovaginal candidiasis identifies a role for the NLRP3 inflammasome.

Bruno VM, Shetty AC, Yano J, Fidel PL Jr, Noverr MC, Peters BM.

MBio. 2015 Apr 21;6(2). pii: e00182-15. doi: 10.1128/mBio.00182-15.

11.

β-Defensin 1 plays a role in acute mucosal defense against Candida albicans.

Tomalka J, Azodi E, Narra HP, Patel K, O'Neill S, Cardwell C, Hall BA, Wilson JM, Hise AG.

J Immunol. 2015 Feb 15;194(4):1788-95. doi: 10.4049/jimmunol.1203239. Epub 2015 Jan 16.

12.

IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis.

Iannitti RG, Napolioni V, Oikonomou V, De Luca A, Galosi C, Pariano M, Massi-Benedetti C, Borghi M, Puccetti M, Lucidi V, Colombo C, Fiscarelli E, Lass-Flörl C, Majo F, Cariani L, Russo M, Porcaro L, Ricciotti G, Ellemunter H, Ratclif L, De Benedictis FM, Talesa VN, Dinarello CA, van de Veerdonk FL, Romani L.

Nat Commun. 2016 Mar 14;7:10791. doi: 10.1038/ncomms10791.

13.

Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.

Sester DP, Sagulenko V, Thygesen SJ, Cridland JA, Loi YS, Cridland SO, Masters SL, Genske U, Hornung V, Andoniou CE, Sweet MJ, Degli-Esposti MA, Schroder K, Stacey KJ.

J Immunol. 2015 Aug 1;195(3):1233-41. doi: 10.4049/jimmunol.1402859. Epub 2015 Jun 26.

14.

Histones activate the NLRP3 inflammasome in Kupffer cells during sterile inflammatory liver injury.

Huang H, Chen HW, Evankovich J, Yan W, Rosborough BR, Nace GW, Ding Q, Loughran P, Beer-Stolz D, Billiar TR, Esmon CT, Tsung A.

J Immunol. 2013 Sep 1;191(5):2665-79. doi: 10.4049/jimmunol.1202733. Epub 2013 Jul 31.

15.

Cutting edge: Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome.

Joly S, Ma N, Sadler JJ, Soll DR, Cassel SL, Sutterwala FS.

J Immunol. 2009 Sep 15;183(6):3578-81. doi: 10.4049/jimmunol.0901323. Epub 2009 Aug 14.

16.

NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages.

Moon JS, Nakahira K, Chung KP, DeNicola GM, Koo MJ, Pabón MA, Rooney KT, Yoon JH, Ryter SW, Stout-Delgado H, Choi AM.

Nat Med. 2016 Sep;22(9):1002-12. doi: 10.1038/nm.4153. Epub 2016 Jul 25.

17.

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.

Zhao Y, Yang J, Shi J, Gong YN, Lu Q, Xu H, Liu L, Shao F.

Nature. 2011 Sep 14;477(7366):596-600. doi: 10.1038/nature10510.

PMID:
21918512
18.

Caspase-11 activation in response to bacterial secretion systems that access the host cytosol.

Casson CN, Copenhaver AM, Zwack EE, Nguyen HT, Strowig T, Javdan B, Bradley WP, Fung TC, Flavell RA, Brodsky IE, Shin S.

PLoS Pathog. 2013;9(6):e1003400. doi: 10.1371/journal.ppat.1003400. Epub 2013 Jun 6.

19.

Involvement of the AIM2, NLRC4, and NLRP3 inflammasomes in caspase-1 activation by Listeria monocytogenes.

Wu J, Fernandes-Alnemri T, Alnemri ES.

J Clin Immunol. 2010 Sep;30(5):693-702. doi: 10.1007/s10875-010-9425-2. Epub 2010 May 20.

20.

Cutting edge: Nlrp10 is essential for protective antifungal adaptive immunity against Candida albicans.

Joly S, Eisenbarth SC, Olivier AK, Williams A, Kaplan DH, Cassel SL, Flavell RA, Sutterwala FS.

J Immunol. 2012 Nov 15;189(10):4713-7. doi: 10.4049/jimmunol.1201715. Epub 2012 Oct 15.

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