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Items: 1 to 20 of 261

1.

Predisposition for disrepair in the aged lung.

Sueblinvong V, Neujahr DC, Mills ST, Roser-Page S, Ritzenthaler JD, Guidot D, Rojas M, Roman J.

Am J Med Sci. 2012 Jul;344(1):41-51. doi: 10.1097/MAJ.0b013e318234c132.

2.

Absence of Thy-1 results in TGF-β induced MMP-9 expression and confers a profibrotic phenotype to human lung fibroblasts.

Ramírez G, Hagood JS, Sanders Y, Ramírez R, Becerril C, Segura L, Barrera L, Selman M, Pardo A.

Lab Invest. 2011 Aug;91(8):1206-18. doi: 10.1038/labinvest.2011.80. Epub 2011 May 16.

3.

Cartilage oligomeric matrix protein in idiopathic pulmonary fibrosis.

Vuga LJ, Milosevic J, Pandit K, Ben-Yehudah A, Chu Y, Richards T, Sciurba J, Myerburg M, Zhang Y, Parwani AV, Gibson KF, Kaminski N.

PLoS One. 2013 Dec 20;8(12):e83120. doi: 10.1371/journal.pone.0083120. eCollection 2013.

4.

The matricellular protein CCN1 enhances TGF-β1/SMAD3-dependent profibrotic signaling in fibroblasts and contributes to fibrogenic responses to lung injury.

Kurundkar AR, Kurundkar D, Rangarajan S, Locy ML, Zhou Y, Liu RM, Zmijewski J, Thannickal VJ.

FASEB J. 2016 Jun;30(6):2135-50. doi: 10.1096/fj.201500173. Epub 2016 Feb 16.

5.

Glycosyltransferases and glycosaminoglycans in bleomycin and transforming growth factor-β1-induced pulmonary fibrosis.

Venkatesan N, Tsuchiya K, Kolb M, Farkas L, Bourhim M, Ouzzine M, Ludwig MS.

Am J Respir Cell Mol Biol. 2014 Mar;50(3):583-94. doi: 10.1165/rcmb.2012-0226OC.

PMID:
24127863
6.

The inhibitory effect of ginsan on TGF-β mediated fibrotic process.

Ahn JY, Kim MH, Lim MJ, Park S, Lee SL, Yun YS, Song JY.

J Cell Physiol. 2011 May;226(5):1241-7. doi: 10.1002/jcp.22452.

PMID:
20945375
7.

Novel Mechanisms for the Antifibrotic Action of Nintedanib.

Rangarajan S, Kurundkar A, Kurundkar D, Bernard K, Sanders YY, Ding Q, Antony VB, Zhang J, Zmijewski J, Thannickal VJ.

Am J Respir Cell Mol Biol. 2016 Jan;54(1):51-9. doi: 10.1165/rcmb.2014-0445OC.

8.

TGF-β1 epigenetically modifies Thy-1 expression in primary lung fibroblasts.

Neveu WA, Mills ST, Staitieh BS, Sueblinvong V.

Am J Physiol Cell Physiol. 2015 Nov 1;309(9):C616-26. doi: 10.1152/ajpcell.00086.2015. Epub 2015 Sep 2.

9.

Lysophosphatidic acid receptor-2 deficiency confers protection against bleomycin-induced lung injury and fibrosis in mice.

Huang LS, Fu P, Patel P, Harijith A, Sun T, Zhao Y, Garcia JG, Chun J, Natarajan V.

Am J Respir Cell Mol Biol. 2013 Dec;49(6):912-22. doi: 10.1165/rcmb.2013-0070OC.

10.

Tubastatin ameliorates pulmonary fibrosis by targeting the TGFβ-PI3K-Akt pathway.

Saito S, Zhuang Y, Shan B, Danchuk S, Luo F, Korfei M, Guenther A, Lasky JA.

PLoS One. 2017 Oct 18;12(10):e0186615. doi: 10.1371/journal.pone.0186615. eCollection 2017.

11.

Compromised peroxisomes in idiopathic pulmonary fibrosis, a vicious cycle inducing a higher fibrotic response via TGF-β signaling.

Oruqaj G, Karnati S, Vijayan V, Kotarkonda LK, Boateng E, Zhang W, Ruppert C, Günther A, Shi W, Baumgart-Vogt E.

Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):E2048-57. doi: 10.1073/pnas.1415111112. Epub 2015 Apr 6.

12.

Arsenic trioxide inhibits transforming growth factor-β1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo.

Luo F, Zhuang Y, Sides MD, Sanchez CG, Shan B, White ES, Lasky JA.

Respir Res. 2014 Apr 24;15:51. doi: 10.1186/1465-9921-15-51.

13.

Human lung parenchyma but not proximal bronchi produces fibroblasts with enhanced TGF-beta signaling and alpha-SMA expression.

Pechkovsky DV, Hackett TL, An SS, Shaheen F, Murray LA, Knight DA.

Am J Respir Cell Mol Biol. 2010 Dec;43(6):641-51. doi: 10.1165/rcmb.2009-0318OC. Epub 2010 Jan 8.

PMID:
20061511
14.

Regulation of TGF-β storage and activation in the human idiopathic pulmonary fibrosis lung.

Leppäranta O, Sens C, Salmenkivi K, Kinnula VL, Keski-Oja J, Myllärniemi M, Koli K.

Cell Tissue Res. 2012 Jun;348(3):491-503. doi: 10.1007/s00441-012-1385-9. Epub 2012 Mar 22.

PMID:
22434388
15.

TGF-β1 induces tissue factor expression in human lung fibroblasts in a PI3K/JNK/Akt-dependent and AP-1-dependent manner.

Wygrecka M, Zakrzewicz D, Taborski B, Didiasova M, Kwapiszewska G, Preissner KT, Markart P.

Am J Respir Cell Mol Biol. 2012 Nov;47(5):614-27. doi: 10.1165/rcmb.2012-0097OC. Epub 2012 Jul 5.

PMID:
22771387
16.

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis.

Liu G, Friggeri A, Yang Y, Milosevic J, Ding Q, Thannickal VJ, Kaminski N, Abraham E.

J Exp Med. 2010 Aug 2;207(8):1589-97. doi: 10.1084/jem.20100035. Epub 2010 Jul 19.

17.

Fibroblasts from idiopathic pulmonary fibrosis and normal lungs differ in growth rate, apoptosis, and tissue inhibitor of metalloproteinases expression.

Ramos C, Montaño M, García-Alvarez J, Ruiz V, Uhal BD, Selman M, Pardo A.

Am J Respir Cell Mol Biol. 2001 May;24(5):591-8.

PMID:
11350829
18.

The antifibrotic effects of relaxin in human renal fibroblasts are mediated in part by inhibition of the Smad2 pathway.

Heeg MH, Koziolek MJ, Vasko R, Schaefer L, Sharma K, Müller GA, Strutz F.

Kidney Int. 2005 Jul;68(1):96-109.

19.

HGF reduces advancing lung fibrosis in mice: a potential role for MMP-dependent myofibroblast apoptosis.

Mizuno S, Matsumoto K, Li MY, Nakamura T.

FASEB J. 2005 Apr;19(6):580-2. Epub 2005 Jan 21.

PMID:
15665032
20.

Protein tyrosine phosphatase α mediates profibrotic signaling in lung fibroblasts through TGF-β responsiveness.

Aschner Y, Khalifah AP, Briones N, Yamashita C, Dolgonos L, Young SK, Campbell MN, Riches DW, Redente EF, Janssen WJ, Henson PM, Sap J, Vacaresse N, Kapus A, McCulloch CA, Zemans RL, Downey GP.

Am J Pathol. 2014 May;184(5):1489-502. doi: 10.1016/j.ajpath.2014.01.016. Epub 2014 Mar 17.

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