Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 96


Functional and biochemical characterization of the baculovirus caspase inhibitor MaviP35.

Brand IL, Green MM, Civciristov S, Pantaki-Eimany D, George C, Gort TR, Huang N, Clem RJ, Hawkins CJ.

Cell Death Dis. 2011 Dec 15;2:e242. doi: 10.1038/cddis.2011.127.


Caspase inhibitors of the P35 family are more active when purified from yeast than bacteria.

Brand IL, Civciristov S, Taylor NL, Talbo GH, Pantaki-Eimany D, Levina V, Clem RJ, Perugini MA, Kvansakul M, Hawkins CJ.

PLoS One. 2012;7(6):e39248. doi: 10.1371/journal.pone.0039248. Epub 2012 Jun 14.


Reactive-site cleavage residues confer target specificity to baculovirus P49, a dimeric member of the P35 family of caspase inhibitors.

Guy MP, Friesen PD.

J Virol. 2008 Aug;82(15):7504-14. doi: 10.1128/JVI.00231-08. Epub 2008 May 28.


Characterization of the apoptosis suppressor protein P49 from the Spodoptera littoralis nucleopolyhedrovirus.

Pei Z, Reske G, Huang Q, Hammock BD, Qi Y, Chejanovsky N.

J Biol Chem. 2002 Dec 13;277(50):48677-84. Epub 2002 Sep 24.


Crystal structure of baculovirus P35 reveals a novel conformational change in the reactive site loop after caspase cleavage.

dela Cruz WP, Friesen PD, Fisher AJ.

J Biol Chem. 2001 Aug 31;276(35):32933-9. Epub 2001 Jun 11.


The p35 relative, p49, inhibits mammalian and Drosophila caspases including DRONC and protects against apoptosis.

Jabbour AM, Ekert PG, Coulson EJ, Knight MJ, Ashley DM, Hawkins CJ.

Cell Death Differ. 2002 Dec;9(12):1311-20.


The Drosophila inhibitor of apoptosis D-IAP1 suppresses cell death induced by the caspase drICE.

Kaiser WJ, Vucic D, Miller LK.

FEBS Lett. 1998 Nov 27;440(1-2):243-8.


Cloning and characterization of a dronc homologue in the silkworm, Bombyx mori.

Suganuma I, Ushiyama T, Yamada H, Iwamoto A, Kobayashi M, Ikeda M.

Insect Biochem Mol Biol. 2011 Nov;41(11):909-21. doi: 10.1016/j.ibmb.2011.08.005. Epub 2011 Sep 8.


Interaction of the baculovirus anti-apoptotic protein p35 with caspases. Specificity, kinetics, and characterization of the caspase/p35 complex.

Zhou Q, Krebs JF, Snipas SJ, Price A, Alnemri ES, Tomaselli KJ, Salvesen GS.

Biochemistry. 1998 Jul 28;37(30):10757-65.


Apoptosis in motion. An apical, P35-insensitive caspase mediates programmed cell death in insect cells.

Manji GA, Friesen PD.

J Biol Chem. 2001 May 18;276(20):16704-10. Epub 2001 Feb 23.


Baculovirus apoptotic suppressor P49 is a substrate inhibitor of initiator caspases resistant to P35 in vivo.

Zoog SJ, Schiller JJ, Wetter JA, Chejanovsky N, Friesen PD.

EMBO J. 2002 Oct 1;21(19):5130-40.


SfDronc, an initiator caspase involved in apoptosis in the fall armyworm Spodoptera frugiperda.

Huang N, Civciristov S, Hawkins CJ, Clem RJ.

Insect Biochem Mol Biol. 2013 May;43(5):444-54. doi: 10.1016/j.ibmb.2013.02.005. Epub 2013 Mar 5.


Apoptotic suppression by baculovirus P35 involves cleavage by and inhibition of a virus-induced CED-3/ICE-like protease.

Bertin J, Mendrysa SM, LaCount DJ, Gaur S, Krebs JF, Armstrong RC, Tomaselli KJ, Friesen PD.

J Virol. 1996 Sep;70(9):6251-9.


Identification of the apoptosis inhibitor gene p49 of Spodoptera litura multicapsid nucleopolyhedrovirus.

Yu M, Li Z, Yang K, Lin T, Gong Y, Pan L, Pang Y.

Virus Genes. 2005 Oct;31(2):145-51.


Novel apoptosis suppressor Apsup from the baculovirus Lymantria dispar multiple nucleopolyhedrovirus precludes apoptosis by preventing proteolytic processing of initiator caspase Dronc.

Yamada H, Kitaguchi K, Hamajima R, Kobayashi M, Ikeda M.

J Virol. 2013 Dec;87(23):12925-34. doi: 10.1128/JVI.02065-13. Epub 2013 Sep 25.

Supplemental Content

Support Center