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Items: 1 to 20 of 345

1.

SerpinB9 expression in human renal tubular epithelial cells is induced by triggering of the viral dsRNA sensors TLR3, MDA5 and RIG-I.

Heutinck KM, Kassies J, Florquin S, ten Berge IJ, Hamann J, Rowshani AT.

Nephrol Dial Transplant. 2012 Jul;27(7):2746-54. doi: 10.1093/ndt/gfr690. Epub 2011 Dec 13.

PMID:
22167597
2.

Viral double-stranded RNA sensors induce antiviral, pro-inflammatory, and pro-apoptotic responses in human renal tubular epithelial cells.

Heutinck KM, Rowshani AT, Kassies J, Claessen N, van Donselaar-van der Pant KA, Bemelman FJ, Eldering E, van Lier RA, Florquin S, Ten Berge IJ, Hamann J.

Kidney Int. 2012 Sep;82(6):664-75. doi: 10.1038/ki.2012.206. Epub 2012 May 30.

3.

Activation of innate immune defense mechanisms contributes to polyomavirus BK-associated nephropathy.

Ribeiro A, Wörnle M, Motamedi N, Anders HJ, Gröne EF, Nitschko H, Kurktschiev P, Debiec H, Kretzler M, Cohen CD, Gröne HJ, Schlöndorff D, Schmid H.

Kidney Int. 2012 Jan;81(1):100-11. doi: 10.1038/ki.2011.311. Epub 2011 Sep 14.

4.

Novel role of toll-like receptor 3, RIG-I and MDA5 in poly (I:C) RNA-induced mesothelial inflammation.

Wörnle M, Sauter M, Kastenmüller K, Ribeiro A, Roeder M, Schmid H, Krötz F, Mussack T, Ladurner R, Sitter T.

Mol Cell Biochem. 2009 Feb;322(1-2):193-206. doi: 10.1007/s11010-008-9957-4. Epub 2008 Nov 13.

PMID:
19005739
5.

TLR3/TRIF signalling pathway regulates IL-32 and IFN-β secretion through activation of RIP-1 and TRAF in the human cornea.

Park GB, Hur DY, Kim YS, Lee HK, Yang JW, Kim D.

J Cell Mol Med. 2015 May;19(5):1042-54. doi: 10.1111/jcmm.12495. Epub 2015 Mar 6.

6.

Melanoma differentiation-associated gene 5 regulates the expression of a chemokine CXCL10 in human mesangial cells: implications for chronic inflammatory renal diseases.

Imaizumi T, Aizawa-Yashiro T, Tsuruga K, Tanaka H, Matsumiya T, Yoshida H, Tatsuta T, Xing F, Hayakari R, Satoh K.

Tohoku J Exp Med. 2012 Sep;228(1):17-26.

7.

Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses.

Wang Q, Nagarkar DR, Bowman ER, Schneider D, Gosangi B, Lei J, Zhao Y, McHenry CL, Burgens RV, Miller DJ, Sajjan U, Hershenson MB.

J Immunol. 2009 Dec 1;183(11):6989-97. doi: 10.4049/jimmunol.0901386. Epub 2009 Nov 4.

8.

Role of RIG-I, MDA-5, and PKR on the expression of inflammatory chemokines induced by synthetic dsRNA in airway epithelial cells.

Matsukura S, Kokubu F, Kurokawa M, Kawaguchi M, Ieki K, Kuga H, Odaka M, Suzuki S, Watanabe S, Homma T, Takeuchi H, Nohtomi K, Adachi M.

Int Arch Allergy Immunol. 2007;143 Suppl 1:80-3. Epub 2007 May 1.

PMID:
17541283
9.

Triggering of the dsRNA sensors TLR3, MDA5, and RIG-I induces CD55 expression in synovial fibroblasts.

Karpus ON, Heutinck KM, Wijnker PJ, Tak PP, Hamann J.

PLoS One. 2012;7(5):e35606. doi: 10.1371/journal.pone.0035606. Epub 2012 May 10.

10.

Regulation and function of the cytosolic viral RNA sensor RIG-I in pancreatic beta cells.

García M, Dogusan Z, Moore F, Sato S, Hartmann G, Eizirik DL, Rasschaert J.

Biochim Biophys Acta. 2009 Nov;1793(11):1768-75. doi: 10.1016/j.bbamcr.2009.09.005. Epub 2009 Sep 10.

11.

Interaction between interferon-stimulated gene 56 and melanoma differentiation-associated gene 5 in Toll-like receptor 3 signaling in normal human mesangial cells.

Imaizumi T, Aizawa-Yashiro T, Matsumiya T, Yoshida H, Watanabe S, Tsuruga K, Tatsuta T, Xing F, Hayakari R, Meng P, Tanaka H.

Am J Nephrol. 2013;37(2):118-25. doi: 10.1159/000346415. Epub 2013 Jan 29.

PMID:
23363937
12.

Innate immune response to double-stranded RNA in biliary epithelial cells is associated with the pathogenesis of biliary atresia.

Harada K, Sato Y, Itatsu K, Isse K, Ikeda H, Yasoshima M, Zen Y, Matsui A, Nakanuma Y.

Hepatology. 2007 Oct;46(4):1146-54.

PMID:
17661372
13.

Induction of interferon-λ contributes to TLR3 and RIG-I activation-mediated inhibition of herpes simplex virus type 2 replication in human cervical epithelial cells.

Zhou L, Li JL, Zhou Y, Liu JB, Zhuang K, Gao JF, Liu S, Sang M, Wu JG, Ho WZ.

Mol Hum Reprod. 2015 Dec;21(12):917-29. doi: 10.1093/molehr/gav058. Epub 2015 Oct 26.

14.

Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium.

Slater L, Bartlett NW, Haas JJ, Zhu J, Message SD, Walton RP, Sykes A, Dahdaleh S, Clarke DL, Belvisi MG, Kon OM, Fujita T, Jeffery PK, Johnston SL, Edwards MR.

PLoS Pathog. 2010 Nov 4;6(11):e1001178. doi: 10.1371/journal.ppat.1001178. Erratum in: PLoS Pathog. 2012 Apr;8(4): doi/10.1371/annotation/c3f58c59-a42f-495b-a4f2-d74d55d72166.

15.

MDA5 complements TLR3 in suppression of neuroblastoma.

Hsu WM, Huang CC, Lee HY, Wu PY, Wu MT, Chuang HC, Lin LL, Chuang JH.

Oncotarget. 2015 Sep 22;6(28):24935-46. doi: 10.18632/oncotarget.4511.

16.

Double-stranded RNA induces an antiviral defense status in epidermal keratinocytes through TLR3-, PKR-, and MDA5/RIG-I-mediated differential signaling.

Kalali BN, Köllisch G, Mages J, Müller T, Bauer S, Wagner H, Ring J, Lang R, Mempel M, Ollert M.

J Immunol. 2008 Aug 15;181(4):2694-704.

17.

Contribution of IPS-1 to polyI:C-induced cytokine production in conjunctival epithelial cells.

Ueta M, Kawai T, Yokoi N, Akira S, Kinoshita S.

Biochem Biophys Res Commun. 2011 Jan 7;404(1):419-23. doi: 10.1016/j.bbrc.2010.11.136. Epub 2010 Dec 3.

PMID:
21130742
18.

DDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signaling.

Miyashita M, Oshiumi H, Matsumoto M, Seya T.

Mol Cell Biol. 2011 Sep;31(18):3802-19. doi: 10.1128/MCB.01368-10. Epub 2011 Jul 26.

19.

Narrowband ultraviolet B inhibits innate cytosolic double-stranded RNA receptors in psoriatic skin and keratinocytes.

Rácz E, Prens EP, Kant M, Florencia E, Jaspers NG, Laman JD, de Ridder D, van der Fits L.

Br J Dermatol. 2011 Apr;164(4):838-47. doi: 10.1111/j.1365-2133.2010.10169.x.

PMID:
21143460
20.

Role of viral receptors TLR3, RIG-I and MDA5 in mesothelial tissue-type plasminogen activator and plasminogen activator inhibitor-1 synthesis.

Wörnle M, Sauter M, Kastenmüller K, Ribeiro A, Mussack T, Ladurner R, Sitter T.

Thromb Haemost. 2009 Jun;101(6):1128-37.

PMID:
19492158

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