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Items: 1 to 20 of 88

1.

Cannabidiol reduces Aβ-induced neuroinflammation and promotes hippocampal neurogenesis through PPARγ involvement.

Esposito G, Scuderi C, Valenza M, Togna GI, Latina V, De Filippis D, Cipriano M, Carratù MR, Iuvone T, Steardo L.

PLoS One. 2011;6(12):e28668. doi: 10.1371/journal.pone.0028668.

2.
3.

Cannabidiol in vivo blunts beta-amyloid induced neuroinflammation by suppressing IL-1beta and iNOS expression.

Esposito G, Scuderi C, Savani C, Steardo L Jr, De Filippis D, Cottone P, Iuvone T, Cuomo V, Steardo L.

Br J Pharmacol. 2007 Aug;151(8):1272-9.

4.

Palmitoylethanolamide exerts neuroprotective effects in mixed neuroglial cultures and organotypic hippocampal slices via peroxisome proliferator-activated receptor-α.

Scuderi C, Valenza M, Stecca C, Esposito G, Carratù MR, Steardo L.

J Neuroinflammation. 2012 Mar 9;9:49. doi: 10.1186/1742-2094-9-21.

5.

Time-dependent vascular actions of cannabidiol in the rat aorta.

O'Sullivan SE, Sun Y, Bennett AJ, Randall MD, Kendall DA.

Eur J Pharmacol. 2009 Jun 10;612(1-3):61-8. doi: 10.1016/j.ejphar.2009.03.010.

PMID:
19285060
6.

The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system.

Campos AC, Ortega Z, Palazuelos J, Fogaça MV, Aguiar DC, Díaz-Alonso J, Ortega-Gutiérrez S, Vázquez-Villa H, Moreira FA, Guzmán M, Galve-Roperh I, Guimarães FS.

Int J Neuropsychopharmacol. 2013 Jul;16(6):1407-19. doi: 10.1017/S1461145712001502.

PMID:
23298518
7.

Cannabidiol protects an in vitro model of the blood-brain barrier from oxygen-glucose deprivation via PPARγ and 5-HT1A receptors.

Hind WH, England TJ, O'Sullivan SE.

Br J Pharmacol. 2016 Mar;173(5):815-25. doi: 10.1111/bph.13368.

8.

Cannabidiol inhibits synaptic transmission in rat hippocampal cultures and slices via multiple receptor pathways.

Ledgerwood CJ, Greenwood SM, Brett RR, Pratt JA, Bushell TJ.

Br J Pharmacol. 2011 Jan;162(1):286-94. doi: 10.1111/j.1476-5381.2010.01015.x.

9.
10.

Peroxisome proliferator-activated receptor gamma up-regulates the Bcl-2 anti-apoptotic protein in neurons and induces mitochondrial stabilization and protection against oxidative stress and apoptosis.

Fuenzalida K, Quintanilla R, Ramos P, Piderit D, Fuentealba RA, Martinez G, Inestrosa NC, Bronfman M.

J Biol Chem. 2007 Dec 21;282(51):37006-15.

11.

Long-term cannabidiol treatment prevents the development of social recognition memory deficits in Alzheimer's disease transgenic mice.

Cheng D, Spiro AS, Jenner AM, Garner B, Karl T.

J Alzheimers Dis. 2014;42(4):1383-96. doi: 10.3233/JAD-140921.

PMID:
25024347
12.

Neuroprotective effect of Chunghyuldan from amyloid beta oligomer induced neuroinflammation in vitro and in vivo.

Kim HG, Kim JY, Whang WW, Oh MS.

Can J Physiol Pharmacol. 2014 Jun;92(6):429-37. doi: 10.1139/cjpp-2013-0229.

PMID:
24820962
13.

Motor effects of the non-psychotropic phytocannabinoid cannabidiol that are mediated by 5-HT1A receptors.

Espejo-Porras F, Fernández-Ruiz J, Pertwee RG, Mechoulam R, García C.

Neuropharmacology. 2013 Dec;75:155-63. doi: 10.1016/j.neuropharm.2013.07.024.

PMID:
23924692
14.

WIN55212-2 attenuates amyloid-beta-induced neuroinflammation in rats through activation of cannabinoid receptors and PPAR-γ pathway.

Fakhfouri G, Ahmadiani A, Rahimian R, Grolla AA, Moradi F, Haeri A.

Neuropharmacology. 2012 Sep;63(4):653-66. doi: 10.1016/j.neuropharm.2012.05.013.

PMID:
22634229
15.

Palmitoylethanolamide counteracts reactive astrogliosis induced by β-amyloid peptide.

Scuderi C, Esposito G, Blasio A, Valenza M, Arietti P, Steardo L Jr, Carnuccio R, De Filippis D, Petrosino S, Iuvone T, Di Marzo V, Steardo L.

J Cell Mol Med. 2011 Dec;15(12):2664-74. doi: 10.1111/j.1582-4934.2011.01267.x.

16.

Ginsenoside Rg1 attenuates β-amyloid generation via suppressing PPARγ-regulated BACE1 activity in N2a-APP695 cells.

Chen LM, Lin ZY, Zhu YG, Lin N, Zhang J, Pan XD, Chen XC.

Eur J Pharmacol. 2012 Jan 30;675(1-3):15-21. doi: 10.1016/j.ejphar.2011.11.039.

PMID:
22166376
17.

Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis.

De Filippis D, Esposito G, Cirillo C, Cipriano M, De Winter BY, Scuderi C, Sarnelli G, Cuomo R, Steardo L, De Man JG, Iuvone T.

PLoS One. 2011;6(12):e28159. doi: 10.1371/journal.pone.0028159.

18.

The marijuana component cannabidiol inhibits beta-amyloid-induced tau protein hyperphosphorylation through Wnt/beta-catenin pathway rescue in PC12 cells.

Esposito G, De Filippis D, Carnuccio R, Izzo AA, Iuvone T.

J Mol Med (Berl). 2006 Mar;84(3):253-8.

PMID:
16389547
19.

Chronic cannabidiol treatment improves social and object recognition in double transgenic APPswe/PS1∆E9 mice.

Cheng D, Low JK, Logge W, Garner B, Karl T.

Psychopharmacology (Berl). 2014 Aug;231(15):3009-17. doi: 10.1007/s00213-014-3478-5.

PMID:
24577515
20.

β-Amyloid exacerbates inflammation in astrocytes lacking fatty acid amide hydrolase through a mechanism involving PPAR-α, PPAR-γ and TRPV1, but not CB₁ or CB₂ receptors.

Benito C, Tolón RM, Castillo AI, Ruiz-Valdepeñas L, Martínez-Orgado JA, Fernández-Sánchez FJ, Vázquez C, Cravatt BF, Romero J.

Br J Pharmacol. 2012 Jun;166(4):1474-89. doi: 10.1111/j.1476-5381.2012.01889.x.

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