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Items: 1 to 20 of 152

1.

Genome-wide profiling of liver X receptor, retinoid X receptor, and peroxisome proliferator-activated receptor α in mouse liver reveals extensive sharing of binding sites.

Boergesen M, Pedersen TÅ, Gross B, van Heeringen SJ, Hagenbeek D, Bindesbøll C, Caron S, Lalloyer F, Steffensen KR, Nebb HI, Gustafsson JÅ, Stunnenberg HG, Staels B, Mandrup S.

Mol Cell Biol. 2012 Feb;32(4):852-67. doi: 10.1128/MCB.06175-11. Epub 2011 Dec 12.

2.

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. II. LXRs suppress lipid degradation gene promoters through inhibition of PPAR signaling.

Ide T, Shimano H, Yoshikawa T, Yahagi N, Amemiya-Kudo M, Matsuzaka T, Nakakuki M, Yatoh S, Iizuka Y, Tomita S, Ohashi K, Takahashi A, Sone H, Gotoda T, Osuga J, Ishibashi S, Yamada N.

Mol Endocrinol. 2003 Jul;17(7):1255-67. Epub 2003 May 1.

PMID:
12730332
3.

Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling.

Yoshikawa T, Ide T, Shimano H, Yahagi N, Amemiya-Kudo M, Matsuzaka T, Yatoh S, Kitamine T, Okazaki H, Tamura Y, Sekiya M, Takahashi A, Hasty AH, Sato R, Sone H, Osuga J, Ishibashi S, Yamada N.

Mol Endocrinol. 2003 Jul;17(7):1240-54. Epub 2003 May 1.

PMID:
12730331
4.

Overlapping transcriptional programs regulated by the nuclear receptors peroxisome proliferator-activated receptor alpha, retinoid X receptor, and liver X receptor in mouse liver.

Anderson SP, Dunn C, Laughter A, Yoon L, Swanson C, Stulnig TM, Steffensen KR, Chandraratna RA, Gustafsson JA, Corton JC.

Mol Pharmacol. 2004 Dec;66(6):1440-52. Epub 2004 Sep 15.

5.

A systems biology approach to the hepatic role of the oxysterol receptor LXR in the regulation of lipogenesis highlights a cross-talk with PPARα.

Ducheix S, Podechard N, Lasserre F, Polizzi A, Pommier A, Murzilli S, Di Lisio C, D'Amore S, Bertrand-Michel J, Montagner A, Pineau T, Loiseau N, Lobaccaro JM, Martin PG, Guillou H.

Biochimie. 2013 Mar;95(3):556-67. doi: 10.1016/j.biochi.2012.09.028. Epub 2012 Oct 10.

PMID:
23063693
6.

Rexinoid bexarotene modulates triglyceride but not cholesterol metabolism via gene-specific permissivity of the RXR/LXR heterodimer in the liver.

Lalloyer F, Pedersen TA, Gross B, Lestavel S, Yous S, Vallez E, Gustafsson JA, Mandrup S, Fiévet C, Staels B, Tailleux A.

Arterioscler Thromb Vasc Biol. 2009 Oct;29(10):1488-95. doi: 10.1161/ATVBAHA.109.189506. Epub 2009 Jul 10.

7.

Intestine-specific regulation of PPARalpha gene transcription by liver X receptors.

Colin S, Bourguignon E, Boullay AB, Tousaint JJ, Huet S, Caira F, Staels B, Lestavel S, Lobaccaro JM, Delerive P.

Endocrinology. 2008 Oct;149(10):5128-35. doi: 10.1210/en.2008-0637. Epub 2008 Jun 19.

PMID:
18566121
8.

A naturally occurring rexinoid, honokiol, can serve as a regulator of various retinoid x receptor heterodimers.

Kotani H, Tanabe H, Mizukami H, Amagaya S, Inoue M.

Biol Pharm Bull. 2012;35(1):1-9.

9.

Molecular determinants of the interactions between SRC-1 and LXR/RXR heterodimers.

Son YL, Lee YC.

FEBS Lett. 2010 Sep 24;584(18):3862-6. doi: 10.1016/j.febslet.2010.07.056. Epub 2010 Aug 1.

10.

Liver X receptor-alpha gene expression is positively regulated by thyroid hormone.

Hashimoto K, Matsumoto S, Yamada M, Satoh T, Mori M.

Endocrinology. 2007 Oct;148(10):4667-75. Epub 2007 Jul 12.

PMID:
17628006
11.

Research resource: transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte-derived dendritic cells.

Széles L, Póliska S, Nagy G, Szatmari I, Szanto A, Pap A, Lindstedt M, Santegoets SJ, Rühl R, Dezsö B, Nagy L.

Mol Endocrinol. 2010 Nov;24(11):2218-31. doi: 10.1210/me.2010-0215. Epub 2010 Sep 22.

12.

Inhibition of liver x receptor/retinoid X receptor-mediated transcription contributes to the proatherogenic effects of arsenic in macrophages in vitro.

Padovani AM, Molina MF, Mann KK.

Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1228-36. doi: 10.1161/ATVBAHA.110.205500. Epub 2010 Mar 25.

13.
14.

Activation of the retinoid X receptor modulates angiotensin II-induced smooth muscle gene expression and inflammation in vascular smooth muscle cells.

Lehman AM, Montford JR, Horita H, Ostriker AC, Weiser-Evans MC, Nemenoff RA, Furgeson SB.

Mol Pharmacol. 2014 Nov;86(5):570-9. doi: 10.1124/mol.114.092163. Epub 2014 Aug 28.

15.

Liver X receptor-retinoid X receptor (LXR-RXR) heterodimer cistrome reveals coordination of LXR and AP1 signaling in keratinocytes.

Shen Q, Bai Y, Chang KC, Wang Y, Burris TP, Freedman LP, Thompson CC, Nagpal S.

J Biol Chem. 2011 Apr 22;286(16):14554-63. doi: 10.1074/jbc.M110.165704. Epub 2011 Feb 24.

16.
17.

The acute phase response is associated with retinoid X receptor repression in rodent liver.

Beigneux AP, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR.

J Biol Chem. 2000 May 26;275(21):16390-9.

18.

PPARα-LXR as a novel metabolostatic signalling axis in skeletal muscle that acts to optimize substrate selection in response to nutrient status.

Caton PW, Holness MJ, Bishop-Bailey D, Sugden MC.

Biochem J. 2011 Aug 1;437(3):521-30. doi: 10.1042/BJ20110702.

PMID:
21609322
19.

Effect of synthetic ligands of PPAR α, β/δ, γ, RAR, RXR and LXR on the fatty acid composition of phospholipids in mice.

Weiss K, Mihály J, Liebisch G, Marosvölgyi T, Schmitz G, Decsi T, Rühl R.

Lipids. 2011 Nov;46(11):1013-20. doi: 10.1007/s11745-011-3593-6. Epub 2011 Jul 27.

PMID:
21792736

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