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Items: 1 to 20 of 116

1.

The in vitro and in vivo comet assays.

Burlinson B.

Methods Mol Biol. 2012;817:143-63. doi: 10.1007/978-1-61779-421-6_8.

PMID:
22147572
2.

The comet assay with multiple mouse organs: comparison of comet assay results and carcinogenicity with 208 chemicals selected from the IARC monographs and U.S. NTP Carcinogenicity Database.

Sasaki YF, Sekihashi K, Izumiyama F, Nishidate E, Saga A, Ishida K, Tsuda S.

Crit Rev Toxicol. 2000 Nov;30(6):629-799. Review.

PMID:
11145306
3.

Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing.

Tice RR, Agurell E, Anderson D, Burlinson B, Hartmann A, Kobayashi H, Miyamae Y, Rojas E, Ryu JC, Sasaki YF.

Environ Mol Mutagen. 2000;35(3):206-21.

PMID:
10737956
4.

Improvement of in vivo genotoxicity assessment: combination of acute tests and integration into standard toxicity testing.

Rothfuss A, Honma M, Czich A, Aardema MJ, Burlinson B, Galloway S, Hamada S, Kirkland D, Heflich RH, Howe J, Nakajima M, O'Donovan M, Plappert-Helbig U, Priestley C, Recio L, Schuler M, Uno Y, Martus HJ.

Mutat Res. 2011 Aug 16;723(2):108-20. doi: 10.1016/j.mrgentox.2010.12.005. Epub 2010 Dec 21.

PMID:
21182982
5.

Testing strategies in mutagenicity and genetic toxicology: an appraisal of the guidelines of the European Scientific Committee for Cosmetics and Non-Food Products for the evaluation of hair dyes.

Kirkland DJ, Henderson L, Marzin D, Müller L, Parry JM, Speit G, Tweats DJ, Williams GM.

Mutat Res. 2005 Dec 30;588(2):88-105. Epub 2005 Dec 2. Review.

PMID:
16326131
6.

Genotoxicity studies of 2,6-dinitrotoluene (2,6-DNT).

Suzuki H, Imamura T, Koeda A, Morimoto K, Wakasa Y, Takei Y, Amemiya R, Hatakeyama H, Satoh H, Sato S.

J Toxicol Sci. 2011 Aug;36(4):499-505.

7.

Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens III. Appropriate follow-up testing in vivo.

Kirkland D, Speit G.

Mutat Res. 2008 Jul 31;654(2):114-32. doi: 10.1016/j.mrgentox.2008.05.002. Epub 2008 May 16.

PMID:
18585956
8.

Evaluation of a multi-endpoint assay in rats, combining the bone-marrow micronucleus test, the Comet assay and the flow-cytometric peripheral blood micronucleus test.

Bowen DE, Whitwell JH, Lillford L, Henderson D, Kidd D, Mc Garry S, Pearce G, Beevers C, Kirkland DJ; Work conducted at Covance Laboratories Ltd., Harrogate.

Mutat Res. 2011 May 18;722(1):7-19. doi: 10.1016/j.mrgentox.2011.02.009. Epub 2011 Feb 25.

PMID:
21356328
9.

Genetic toxicity of naphthalene: a review.

Schreiner CA.

J Toxicol Environ Health B Crit Rev. 2003 Mar-Apr;6(2):161-83. Review.

PMID:
12554433
10.

How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop.

Kirkland D, Pfuhler S, Tweats D, Aardema M, Corvi R, Darroudi F, Elhajouji A, Glatt H, Hastwell P, Hayashi M, Kasper P, Kirchner S, Lynch A, Marzin D, Maurici D, Meunier JR, Müller L, Nohynek G, Parry J, Parry E, Thybaud V, Tice R, van Benthem J, Vanparys P, White P.

Mutat Res. 2007 Mar 30;628(1):31-55. Epub 2007 Jan 13.

PMID:
17293159
11.

Experiences with the in vivo and in vitro comet assay in regulatory testing.

Frötschl R.

Mutagenesis. 2015 Jan;30(1):51-7. doi: 10.1093/mutage/geu069.

PMID:
25527728
12.

Collaborative study on fifteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies.

Rothfuss A, O'Donovan M, De Boeck M, Brault D, Czich A, Custer L, Hamada S, Plappert-Helbig U, Hayashi M, Howe J, Kraynak AR, van der Leede BJ, Nakajima M, Priestley C, Thybaud V, Saigo K, Sawant S, Shi J, Storer R, Struwe M, Vock E, Galloway S.

Mutat Res. 2010 Sep 30;702(1):40-69. doi: 10.1016/j.mrgentox.2010.07.006. Epub 2010 Jul 23.

PMID:
20656055
14.

Assessment of genotoxicity induced by 7,12-dimethylbenz(a)anthracene or diethylnitrosamine in the Pig-a, micronucleus and Comet assays integrated into 28-day repeat dose studies.

Shi J, Krsmanovic L, Bruce S, Kelly T, Paranjpe M, Szabo K, Arevalo M, Atta-Safoh S, Debelie F, LaForce MK, Sly J, Springer S.

Environ Mol Mutagen. 2011 Dec;52(9):711-20. doi: 10.1002/em.20678. Epub 2011 Oct 4.

PMID:
21976072
15.

Aloe-emodin-induced DNA fragmentation in the mouse in vivo comet assay.

Nesslany F, Simar-Meintières S, Ficheux H, Marzin D.

Mutat Res. 2009 Aug;678(1):13-9. doi: 10.1016/j.mrgentox.2009.06.004. Epub 2009 Jun 24.

PMID:
19559101
16.

The in vivo comet assay: use and status in genotoxicity testing.

Brendler-Schwaab S, Hartmann A, Pfuhler S, Speit G.

Mutagenesis. 2005 Jul;20(4):245-54. Epub 2005 May 17. Review.

PMID:
15899933
17.

The comet assay as an indicator test for germ cell genotoxicity.

Speit G, Vasquez M, Hartmann A.

Mutat Res. 2009 Jan-Feb;681(1):3-12. doi: 10.1016/j.mrrev.2008.03.005. Epub 2008 Mar 30. Review.

PMID:
18462987
18.

Combining the in vivo comet and micronucleus assays: a practical approach to genotoxicity testing and data interpretation.

Vasquez MZ.

Mutagenesis. 2010 Mar;25(2):187-99. doi: 10.1093/mutage/gep060. Epub 2009 Dec 6.

19.

In vivo Comet assay on isolated kidney cells to distinguish genotoxic carcinogens from epigenetic carcinogens or cytotoxic compounds.

Nesslany F, Zennouche N, Simar-Meintières S, Talahari I, Nkili-Mboui EN, Marzin D.

Mutat Res. 2007 Jun 15;630(1-2):28-41. Epub 2007 Apr 19.

PMID:
17507283
20.

Methyleugenol genotoxicity in the Fischer 344 rat using the comet assay and pathway-focused gene expression profiling.

Ding W, Levy DD, Bishop ME, Lyn-Cook Lascelles E, Kulkarni R, Chang CW, Aidoo A, Manjanatha MG.

Toxicol Sci. 2011 Sep;123(1):103-12. doi: 10.1093/toxsci/kfr153. Epub 2011 Jun 9.

PMID:
21659616

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