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Items: 1 to 20 of 98

1.

Prevalence of single nucleotide polymorphisms in the Plasmodium falciparum multidrug resistance gene (Pfmdr-1) in Korogwe District in Tanzania before and after introduction of artemisinin-based combination therapy.

Thomsen TT, Ishengoma DS, Mmbando BP, Lusingu JP, Vestergaard LS, Theander TG, Lemnge MM, Bygbjerg IC, Alifrangis M.

Am J Trop Med Hyg. 2011 Dec;85(6):979-83. doi: 10.4269/ajtmh.2011.11-0071.

2.

Temporal trends of molecular markers associated with artemether-lumefantrine tolerance/resistance in Bagamoyo district, Tanzania.

Malmberg M, Ngasala B, Ferreira PE, Larsson E, Jovel I, Hjalmarsson A, Petzold M, Premji Z, Gil JP, Björkman A, Mårtensson A.

Malar J. 2013 Mar 18;12:103. doi: 10.1186/1475-2875-12-103.

3.

Rapid selection of Plasmodium falciparum chloroquine resistance transporter gene and multidrug resistance gene-1 haplotypes associated with past chloroquine and present artemether-lumefantrine use in Inhambane District, southern Mozambique.

Thomsen TT, Madsen LB, Hansson HH, Tomás EV, Charlwood D, Bygbjerg IC, Alifrangis M.

Am J Trop Med Hyg. 2013 Mar;88(3):536-41. doi: 10.4269/ajtmh.12-0525. Epub 2013 Feb 4.

4.

Efficacy of artesunate plus amodiaquine versus that of artemether-lumefantrine for the treatment of uncomplicated childhood Plasmodium falciparum malaria in Zanzibar, Tanzania.

Mårtensson A, Strömberg J, Sisowath C, Msellem MI, Gil JP, Montgomery SM, Olliaro P, Ali AS, Björkman A.

Clin Infect Dis. 2005 Oct 15;41(8):1079-86. Epub 2005 Sep 13.

PMID:
16163624
5.

The role of pfmdr1 in Plasmodium falciparum tolerance to artemether-lumefantrine in Africa.

Sisowath C, Ferreira PE, Bustamante LY, Dahlström S, Mårtensson A, Björkman A, Krishna S, Gil JP.

Trop Med Int Health. 2007 Jun;12(6):736-42.

6.

Therapeutic efficacy of artemether-lumefantrine in uncomplicated falciparum malaria in India.

Valecha N, Srivastava P, Mohanty SS, Mittra P, Sharma SK, Tyagi PK, Pradhan K, Dev V, Singh R, Dash AP, Sharma YD.

Malar J. 2009 May 19;8:107. doi: 10.1186/1475-2875-8-107.

7.

Temporal trends in prevalence of Plasmodium falciparum molecular markers selected for by artemether-lumefantrine treatment in pre-ACT and post-ACT parasites in western Kenya.

Achieng AO, Muiruri P, Ingasia LA, Opot BH, Juma DW, Yeda R, Ngalah BS, Ogutu BR, Andagalu B, Akala HM, Kamau E.

Int J Parasitol Drugs Drug Resist. 2015 Jun 29;5(3):92-9. doi: 10.1016/j.ijpddr.2015.05.005. eCollection 2015 Dec.

8.

Prevalence of pfmdr1 alleles associated with artemether-lumefantrine tolerance/resistance in Maputo before and after the implementation of artemisinin-based combination therapy.

Lobo E, de Sousa B, Rosa S, Figueiredo P, Lobo L, Pateira S, Fernandes N, Nogueira F.

Malar J. 2014 Aug 6;13:300. doi: 10.1186/1475-2875-13-300.

9.

Surveillance of artemether-lumefantrine associated Plasmodium falciparum multidrug resistance protein-1 gene polymorphisms in Tanzania.

Kavishe RA, Paulo P, Kaaya RD, Kalinga A, van Zwetselaar M, Chilongola J, Roper C, Alifrangis M.

Malar J. 2014 Jul 9;13:264. doi: 10.1186/1475-2875-13-264.

10.

In Vitro and Molecular Surveillance for Antimalarial Drug Resistance in Plasmodium falciparum Parasites in Western Kenya Reveals Sustained Artemisinin Sensitivity and Increased Chloroquine Sensitivity.

Lucchi NW, Komino F, Okoth SA, Goldman I, Onyona P, Wiegand RE, Juma E, Shi YP, Barnwell JW, Udhayakumar V, Kariuki S.

Antimicrob Agents Chemother. 2015 Dec;59(12):7540-7. doi: 10.1128/AAC.01894-15. Epub 2015 Sep 21.

11.

Molecular and pharmacological determinants of the therapeutic response to artemether-lumefantrine in multidrug-resistant Plasmodium falciparum malaria.

Price RN, Uhlemann AC, van Vugt M, Brockman A, Hutagalung R, Nair S, Nash D, Singhasivanon P, Anderson TJ, Krishna S, White NJ, Nosten F.

Clin Infect Dis. 2006 Jun 1;42(11):1570-7. Epub 2006 Apr 26.

12.

Plasmodium falciparum population dynamics during the early phase of anti-malarial drug treatment in Tanzanian children with acute uncomplicated malaria.

Carlsson AM, Ngasala BE, Dahlström S, Membi C, Veiga IM, Rombo L, Abdulla S, Premji Z, Gil JP, Björkman A, Mårtensson A.

Malar J. 2011 Dec 20;10:380. doi: 10.1186/1475-2875-10-380.

13.

In vivo selection of Plasmodium falciparum parasites carrying the chloroquine-susceptible pfcrt K76 allele after treatment with artemether-lumefantrine in Africa.

Sisowath C, Petersen I, Veiga MI, Mårtensson A, Premji Z, Björkman A, Fidock DA, Gil JP.

J Infect Dis. 2009 Mar 1;199(5):750-7. doi: 10.1086/596738.

14.

Comparative efficacies of artemisinin combination therapies in Plasmodium falciparum malaria and polymorphism of pfATPase6, pfcrt, pfdhfr, and pfdhps genes in tea gardens of Jalpaiguri District, India.

Saha P, Guha SK, Das S, Mullick S, Ganguly S, Biswas A, Bera DK, Chattopadhyay G, Das M, Kundu PK, Ray K, Maji AK.

Antimicrob Agents Chemother. 2012 May;56(5):2511-7. doi: 10.1128/AAC.05388-11. Epub 2012 Feb 6.

15.

Assessment of the therapeutic efficacy of artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in northern KwaZulu-Natal: an observational cohort study.

Vaughan-Williams CH, Raman J, Raswiswi E, Immelman E, Reichel H, Gate K, Knight S.

Malar J. 2012 Dec 28;11:434. doi: 10.1186/1475-2875-11-434.

16.

Coartem (artemether-lumefantrine) in Africa: the beginning of the end?

Hastings IM, Ward SA.

J Infect Dis. 2005 Oct 1;192(7):1303-4; author reply 1304-5. No abstract available.

PMID:
16136476
17.

In vivo selection of Plasmodium falciparum pfmdr1 86N coding alleles by artemether-lumefantrine (Coartem).

Sisowath C, Strömberg J, Mårtensson A, Msellem M, Obondo C, Björkman A, Gil JP.

J Infect Dis. 2005 Mar 15;191(6):1014-7. Epub 2005 Feb 8.

PMID:
15717281
18.

Selection of known Plasmodium falciparum resistance-mediating polymorphisms by artemether-lumefantrine and amodiaquine-sulfadoxine-pyrimethamine but not dihydroartemisinin-piperaquine in Burkina Faso.

Somé AF, Séré YY, Dokomajilar C, Zongo I, Rouamba N, Greenhouse B, Ouédraogo JB, Rosenthal PJ.

Antimicrob Agents Chemother. 2010 May;54(5):1949-54. doi: 10.1128/AAC.01413-09. Epub 2010 Mar 15.

19.

Increased prevalence of the Plasmodium falciparum Pfmdr1 86N genotype among field isolates from Franceville, Gabon after replacement of chloroquine by artemether-lumefantrine and artesunate-mefloquine.

Lekana-Douki JB, Dinzouna Boutamba SD, Zatra R, Zang Edou SE, Ekomy H, Bisvigou U, Toure-Ndouo FS.

Infect Genet Evol. 2011 Mar;11(2):512-7. doi: 10.1016/j.meegid.2011.01.003. Epub 2011 Jan 17.

PMID:
21251998
20.

Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin.

Sidhu AB, Uhlemann AC, Valderramos SG, Valderramos JC, Krishna S, Fidock DA.

J Infect Dis. 2006 Aug 15;194(4):528-35. Epub 2006 Jul 11.

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