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Items: 1 to 20 of 189

1.

The mGluR7 allosteric agonist AMN082 produces antidepressant-like effects by modulating glutamatergic signaling.

Bradley SR, Uslaner JM, Flick RB, Lee A, Groover KM, Hutson PH.

Pharmacol Biochem Behav. 2012 Mar;101(1):35-40. doi: 10.1016/j.pbb.2011.11.006. Epub 2011 Nov 25.

PMID:
22138407
2.

The antidepressant-like action of metabotropic glutamate 7 receptor agonist N,N'-bis(diphenylmethyl)-1,2-ethanediamine (AMN082) is serotonin-dependent.

Pałucha-Poniewiera A, Brański P, Lenda T, Pilc A.

J Pharmacol Exp Ther. 2010 Sep 1;334(3):1066-74. doi: 10.1124/jpet.110.169730. Epub 2010 Jun 18.

3.

Activation of the mTOR signaling pathway in the antidepressant-like activity of the mGlu5 antagonist MTEP and the mGlu7 agonist AMN082 in the FST in rats.

Pałucha-Poniewiera A, Szewczyk B, Pilc A.

Neuropharmacology. 2014 Jul;82:59-68. doi: 10.1016/j.neuropharm.2014.03.001. Epub 2014 Mar 12.

PMID:
24631968
4.

The metabotropic glutamate receptor 7 allosteric modulator AMN082: a monoaminergic agent in disguise?

Sukoff Rizzo SJ, Leonard SK, Gilbert A, Dollings P, Smith DL, Zhang MY, Di L, Platt BJ, Neal S, Dwyer JM, Bender CN, Zhang J, Lock T, Kowal D, Kramer A, Randall A, Huselton C, Vishwanathan K, Tse SY, Butera J, Ring RH, Rosenzweig-Lipson S, Hughes ZA, Dunlop J.

J Pharmacol Exp Ther. 2011 Jul;338(1):345-52. doi: 10.1124/jpet.110.177378. Epub 2011 Apr 20.

5.
6.

AMPA glutamate receptors mediate the antidepressant-like effects of N-acetylcysteine in the mouse tail suspension test.

Linck VM, Costa-Campos L, Pilz LK, Garcia CR, Elisabetsky E.

Behav Pharmacol. 2012 Apr;23(2):171-7. doi: 10.1097/FBP.0b013e3283512c3a.

PMID:
22327021
7.

Involvement of AMPA receptor in both the rapid and sustained antidepressant-like effects of ketamine in animal models of depression.

Koike H, Iijima M, Chaki S.

Behav Brain Res. 2011 Oct 10;224(1):107-11. doi: 10.1016/j.bbr.2011.05.035. Epub 2011 Jun 6.

PMID:
21669235
8.
9.

Activation of the mGlu7 receptor elicits antidepressant-like effects in mice.

Palucha A, Klak K, Branski P, van der Putten H, Flor PJ, Pilc A.

Psychopharmacology (Berl). 2007 Nov;194(4):555-62. Epub 2007 Jul 12.

PMID:
17622518
10.

The selective metabotropic glutamate receptor 7 allosteric agonist AMN082 prevents reinstatement of extinguished ethanol-induced conditioned place preference in mice.

Bahi A.

Pharmacol Biochem Behav. 2012 Apr;101(2):193-200. doi: 10.1016/j.pbb.2012.01.008. Epub 2012 Jan 16.

PMID:
22269296
11.

A selective mGlu7 receptor antagonist MMPIP reversed antidepressant-like effects of AMN082 in rats.

Pałucha-Poniewiera A, Pilc A.

Behav Brain Res. 2013 Feb 1;238:109-12. doi: 10.1016/j.bbr.2012.10.004. Epub 2012 Oct 17.

PMID:
23085340
12.

In vitro pharmacological characterization of novel isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists.

Suzuki G, Tsukamoto N, Fushiki H, Kawagishi A, Nakamura M, Kurihara H, Mitsuya M, Ohkubo M, Ohta H.

J Pharmacol Exp Ther. 2007 Oct;323(1):147-56. Epub 2007 Jul 3.

13.

AMN082, an allosteric mGluR7 agonist that inhibits afferent glutamatergic transmission in rat basolateral amygdala.

Ugolini A, Large CH, Corsi M.

Neuropharmacology. 2008 Sep;55(4):532-6. doi: 10.1016/j.neuropharm.2008.04.020. Epub 2008 Apr 30.

PMID:
18533198
14.

Pharmacological modulation of mGluR7 with AMN082 and MMPIP exerts specific influences on alcohol consumption and preference in rats.

Bahi A, Fizia K, Dietz M, Gasparini F, Flor PJ.

Addict Biol. 2012 Mar;17(2):235-47. doi: 10.1111/j.1369-1600.2010.00310.x. Epub 2011 Mar 11.

PMID:
21392179
15.

Does increasing the ratio of AMPA-to-NMDA receptor mediated neurotransmission engender antidepressant action? Studies in the mouse forced swim and tail suspension tests.

Andreasen JT, Gynther M, Rygaard A, Bøgelund T, Nielsen SD, Clausen RP, Mogensen J, Pickering DS.

Neurosci Lett. 2013 Jun 24;546:6-10. doi: 10.1016/j.neulet.2013.04.045. Epub 2013 May 2.

PMID:
23643996
16.

The antidepressant-like effects of glutamatergic drugs ketamine and AMPA receptor potentiator LY 451646 are preserved in bdnf⁺/⁻ heterozygous null mice.

Lindholm JS, Autio H, Vesa L, Antila H, Lindemann L, Hoener MC, Skolnick P, Rantamäki T, Castrén E.

Neuropharmacology. 2012 Jan;62(1):391-7. doi: 10.1016/j.neuropharm.2011.08.015. Epub 2011 Aug 16.

PMID:
21867718
17.

A selective metabotropic glutamate receptor 7 agonist: activation of receptor signaling via an allosteric site modulates stress parameters in vivo.

Mitsukawa K, Yamamoto R, Ofner S, Nozulak J, Pescott O, Lukic S, Stoehr N, Mombereau C, Kuhn R, McAllister KH, van der Putten H, Cryan JF, Flor PJ.

Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18712-7. Epub 2005 Dec 9.

18.

NMDA receptor blockade by ketamine abrogates lipopolysaccharide-induced depressive-like behavior in C57BL/6J mice.

Walker AK, Budac DP, Bisulco S, Lee AW, Smith RA, Beenders B, Kelley KW, Dantzer R.

Neuropsychopharmacology. 2013 Aug;38(9):1609-16. doi: 10.1038/npp.2013.71. Epub 2013 Mar 19.

19.

Requirement of AMPA receptor stimulation for the sustained antidepressant activity of ketamine and LY341495 during the forced swim test in rats.

Koike H, Chaki S.

Behav Brain Res. 2014 Sep 1;271:111-5. doi: 10.1016/j.bbr.2014.05.065. Epub 2014 Jun 5.

PMID:
24909673
20.

Ketamine, but not MK-801, produces antidepressant-like effects in rats responding on a differential-reinforcement-of-low-rate operant schedule.

Hillhouse TM, Porter JH.

Behav Pharmacol. 2014 Feb;25(1):80-91. doi: 10.1097/FBP.0000000000000014.

PMID:
24370559

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