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Items: 1 to 20 of 116

1.

Loss of Dnmt3b function upregulates the tumor modifier Ment and accelerates mouse lymphomagenesis.

Hlady RA, Novakova S, Opavska J, Klinkebiel D, Peters SL, Bies J, Hannah J, Iqbal J, Anderson KM, Siebler HM, Smith LM, Greiner TC, Bastola D, Joshi S, Lockridge O, Simpson MA, Felsher DW, Wagner KU, Chan WC, Christman JK, Opavsky R.

J Clin Invest. 2012 Jan;122(1):163-77. doi: 10.1172/JCI57292. Epub 2011 Dec 1.

2.

DNMT3B7 expression related to MENT expression and its promoter methylation in human lymphomas.

Alkebsi L, Handa H, Sasaki Y, Osaki Y, Yanagisawa K, Ogawa Y, Yokohama A, Hattori H, Koiso H, Saitoh T, Mitsui T, Tsukamoto N, Nojima Y, Murakami H.

Leuk Res. 2013 Dec;37(12):1662-7. doi: 10.1016/j.leukres.2013.09.014. Epub 2013 Sep 21.

PMID:
24094886
3.

Methylation-independent repression of Dnmt3b contributes to oncogenic activity of Dnmt3a in mouse MYC-induced T-cell lymphomagenesis.

Haney SL, Hlady RA, Opavska J, Klinkebiel D, Pirruccello SJ, Dutta S, Datta K, Simpson MA, Wu L, Opavsky R.

Oncogene. 2015 Oct;34(43):5436-5446. doi: 10.1038/onc.2014.472. Epub 2015 Feb 2.

4.

DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis.

Shah MY, Vasanthakumar A, Barnes NY, Figueroa ME, Kamp A, Hendrick C, Ostler KR, Davis EM, Lin S, Anastasi J, Le Beau MM, Moskowitz IP, Melnick A, Pytel P, Godley LA.

Cancer Res. 2010 Jul 15;70(14):5840-50. doi: 10.1158/0008-5472.CAN-10-0847. Epub 2010 Jun 29.

5.

Essential role for Dnmt1 in the prevention and maintenance of MYC-induced T-cell lymphomas.

Peters SL, Hlady RA, Opavska J, Klinkebiel D, Novakova S, Smith LM, Lewis RE, Karpf AR, Simpson MA, Wu L, Opavsky R.

Mol Cell Biol. 2013 Nov;33(21):4321-33. doi: 10.1128/MCB.00776-13. Epub 2013 Sep 3.

6.

Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis.

Vasanthakumar A, Lepore JB, Zegarek MH, Kocherginsky M, Singh M, Davis EM, Link PA, Anastasi J, Le Beau MM, Karpf AR, Godley LA.

Blood. 2013 Mar 14;121(11):2059-63. doi: 10.1182/blood-2012-04-421065. Epub 2013 Jan 11.

7.

∆ DNMT3B4-del Contributes to Aberrant DNA Methylation Patterns in Lung Tumorigenesis.

Ma MZ, Lin R, Carrillo J, Bhutani M, Pathak A, Ren H, Li Y, Song J, Mao L.

EBioMedicine. 2015 Sep 7;2(10):1340-50. doi: 10.1016/j.ebiom.2015.09.002. eCollection 2015 Oct.

8.

MTSS1, a novel target of DNA methyltransferase 3B, functions as a tumor suppressor in hepatocellular carcinoma.

Fan H, Chen L, Zhang F, Quan Y, Su X, Qiu X, Zhao Z, Kong KL, Dong S, Song Y, Chan TH, Guan XY.

Oncogene. 2012 May 3;31(18):2298-308. doi: 10.1038/onc.2011.411. Epub 2011 Sep 12.

PMID:
21909138
9.

Loss of Dnmt3b accelerates MLL-AF9 leukemia progression.

Zheng Y, Zhang H, Wang Y, Li X, Lu P, Dong F, Pang Y, Ma S, Cheng H, Hao S, Tang F, Yuan W, Zhang X, Cheng T.

Leukemia. 2016 Dec;30(12):2373-2384. doi: 10.1038/leu.2016.112. Epub 2016 May 2.

PMID:
27133822
10.

Antiproliferative effects of DNA methyltransferase 3B depletion are not associated with DNA demethylation.

Hagemann S, Kuck D, Stresemann C, Prinz F, Brueckner B, Mund C, Mumberg D, Sommer A.

PLoS One. 2012;7(5):e36125. doi: 10.1371/journal.pone.0036125. Epub 2012 May 1.

11.

HOXB13, a target of DNMT3B, is methylated at an upstream CpG island, and functions as a tumor suppressor in primary colorectal tumors.

Ghoshal K, Motiwala T, Claus R, Yan P, Kutay H, Datta J, Majumder S, Bai S, Majumder A, Huang T, Plass C, Jacob ST.

PLoS One. 2010 Apr 29;5(4):e10338. doi: 10.1371/journal.pone.0010338.

12.

DNMT3B overexpression by deregulation of FOXO3a-mediated transcription repression and MDM2 overexpression in lung cancer.

Yang YC, Tang YA, Shieh JM, Lin RK, Hsu HS, Wang YC.

J Thorac Oncol. 2014 Sep;9(9):1305-15. doi: 10.1097/JTO.0000000000000240.

13.

Suppression of intestinal neoplasia by deletion of Dnmt3b.

Lin H, Yamada Y, Nguyen S, Linhart H, Jackson-Grusby L, Meissner A, Meletis K, Lo G, Jaenisch R.

Mol Cell Biol. 2006 Apr;26(8):2976-83.

15.

Global identification of genes targeted by DNMT3b for epigenetic silencing in lung cancer.

Teneng I, Tellez CS, Picchi MA, Klinge DM, Yingling CM, Snider AM, Liu Y, Belinsky SA.

Oncogene. 2015 Jan 29;34(5):621-30. doi: 10.1038/onc.2013.580. Epub 2014 Jan 27.

PMID:
24469050
16.

Polymorphisms in the DNA methyltransferase 3b gene and prostate cancer risk.

Singal R, Das PM, Manoharan M, Reis IM, Schlesselman JJ.

Oncol Rep. 2005 Aug;14(2):569-73.

PMID:
16012746
17.

Analysis of DNA methylation change induced by Dnmt3b in mouse hepatocytes.

Takahashi M, Kamei Y, Ehara T, Yuan X, Suganami T, Takai-Igarashi T, Hatada I, Ogawa Y.

Biochem Biophys Res Commun. 2013 May 17;434(4):873-8. doi: 10.1016/j.bbrc.2013.04.041. Epub 2013 Apr 20.

PMID:
23611774
18.
19.

A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA methylation patterns and displays altered DNA binding.

Gopalakrishnan S, Van Emburgh BO, Shan J, Su Z, Fields CR, Vieweg J, Hamazaki T, Schwartz PH, Terada N, Robertson KD.

Mol Cancer Res. 2009 Oct;7(10):1622-34. doi: 10.1158/1541-7786.MCR-09-0018. Epub 2009 Oct 13.

20.

Kaempferol Modulates DNA Methylation and Downregulates DNMT3B in Bladder Cancer.

Qiu W, Lin J, Zhu Y, Zhang J, Zeng L, Su M, Tian Y.

Cell Physiol Biochem. 2017;41(4):1325-1335. doi: 10.1159/000464435. Epub 2017 Mar 8.

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