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Items: 1 to 20 of 98

1.

The C terminus of Bax inhibitor-1 forms a Ca2+-permeable channel pore.

Bultynck G, Kiviluoto S, Henke N, Ivanova H, Schneider L, Rybalchenko V, Luyten T, Nuyts K, De Borggraeve W, Bezprozvanny I, Parys JB, De Smedt H, Missiaen L, Methner A.

J Biol Chem. 2012 Jan 20;287(4):2544-57. doi: 10.1074/jbc.M111.275354. Epub 2011 Nov 28.

2.

Bax Inhibitor-1-mediated Ca2+ leak is decreased by cytosolic acidosis.

Kiviluoto S, Luyten T, Schneider L, Lisak D, Rojas-Rivera D, Welkenhuyzen K, Missaen L, De Smedt H, Parys JB, Hetz C, Methner A, Bultynck G.

Cell Calcium. 2013 Sep;54(3):186-92. doi: 10.1016/j.ceca.2013.06.002. Epub 2013 Jul 16.

PMID:
23867001
3.

Bax inhibitor-1 is likely a pH-sensitive calcium leak channel, not a H+/Ca2+ exchanger.

Bultynck G, Kiviluoto S, Methner A.

Sci Signal. 2014 Sep 16;7(343):pe22. doi: 10.1126/scisignal.2005764.

PMID:
25227609
4.
5.

Bax Inhibitor-1 Is a pH-dependent regulator of Ca2+ channel activity in the endoplasmic reticulum.

Kim HR, Lee GH, Ha KC, Ahn T, Moon JY, Lee BJ, Cho SG, Kim S, Seo YR, Shin YJ, Chae SW, Reed JC, Chae HJ.

J Biol Chem. 2008 Jun 6;283(23):15946-55. doi: 10.1074/jbc.M800075200. Epub 2008 Mar 31.

6.

Calmodulin regulation of the calcium-leak channel Sec61 is unique to vertebrates.

Harsman A, Kopp A, Wagner R, Zimmermann R, Jung M.

Channels (Austin). 2011 Jul-Aug;5(4):293-8. Epub 2011 Jul 1.

PMID:
21558796
7.

Biogenesis and topology of the transient receptor potential Ca2+ channel TRPC1.

Dohke Y, Oh YS, Ambudkar IS, Turner RJ.

J Biol Chem. 2004 Mar 26;279(13):12242-8. Epub 2004 Jan 5.

8.

BI-1 regulates endoplasmic reticulum Ca2+ homeostasis downstream of Bcl-2 family proteins.

Xu C, Xu W, Palmer AE, Reed JC.

J Biol Chem. 2008 Apr 25;283(17):11477-84. doi: 10.1074/jbc.M708385200. Epub 2008 Feb 25.

9.

Ribosome-translocon complex mediates calcium leakage from endoplasmic reticulum stores.

Van Coppenolle F, Vanden Abeele F, Slomianny C, Flourakis M, Hesketh J, Dewailly E, Prevarskaya N.

J Cell Sci. 2004 Aug 15;117(Pt 18):4135-42. Epub 2004 Jul 27.

10.

Presenilins as endoplasmic reticulum calcium leak channels and Alzheimer's disease pathogenesis.

Supnet C, Bezprozvanny I.

Sci China Life Sci. 2011 Aug;54(8):744-51. doi: 10.1007/s11427-011-4201-y. Epub 2011 Jul 24. Review.

PMID:
21786197
11.
12.

Familial Alzheimer disease-linked mutations specifically disrupt Ca2+ leak function of presenilin 1.

Nelson O, Tu H, Lei T, Bentahir M, de Strooper B, Bezprozvanny I.

J Clin Invest. 2007 May;117(5):1230-9. Epub 2007 Apr 12.

13.

Sec61 complexes form ubiquitous ER Ca2+ leak channels.

Lang S, Erdmann F, Jung M, Wagner R, Cavalie A, Zimmermann R.

Channels (Austin). 2011 May-Jun;5(3):228-35. Epub 2011 May 1.

PMID:
21406962
14.

Evolutionarily conserved cytoprotection provided by Bax Inhibitor-1 homologs from animals, plants, and yeast.

Chae HJ, Ke N, Kim HR, Chen S, Godzik A, Dickman M, Reed JC.

Gene. 2003 Dec 24;323:101-13.

PMID:
14659883
16.

Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum.

Oakes SA, Scorrano L, Opferman JT, Bassik MC, Nishino M, Pozzan T, Korsmeyer SJ.

Proc Natl Acad Sci U S A. 2005 Jan 4;102(1):105-10. Epub 2004 Dec 21.

17.

Molecular characterization of two plant BI-1 homologues which suppress Bax-induced apoptosis in human 293 cells.

Bolduc N, Ouellet M, Pitre F, Brisson LF.

Planta. 2003 Jan;216(3):377-86. Epub 2002 Oct 8.

PMID:
12520328
18.

Lack of evidence for presenilins as endoplasmic reticulum Ca2+ leak channels.

Shilling D, Mak DO, Kang DE, Foskett JK.

J Biol Chem. 2012 Mar 30;287(14):10933-44. doi: 10.1074/jbc.M111.300491. Epub 2012 Feb 6.

19.

The homocysteine-inducible endoplasmic reticulum stress protein counteracts calcium store depletion and induction of CCAAT enhancer-binding protein homologous protein in a neurotoxin model of Parkinson disease.

Chigurupati S, Wei Z, Belal C, Vandermey M, Kyriazis GA, Arumugam TV, Chan SL.

J Biol Chem. 2009 Jul 3;284(27):18323-33. doi: 10.1074/jbc.M109.020891. Epub 2009 May 15.

20.

Modulation of ER stress and apoptosis by endoplasmic reticulum calcium leak via translocon during unfolded protein response: involvement of GRP78.

Hammadi M, Oulidi A, Gackière F, Katsogiannou M, Slomianny C, Roudbaraki M, Dewailly E, Delcourt P, Lepage G, Lotteau S, Ducreux S, Prevarskaya N, Van Coppenolle F.

FASEB J. 2013 Apr;27(4):1600-9. doi: 10.1096/fj.12-218875. Epub 2013 Jan 15.

PMID:
23322163

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