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Items: 1 to 20 of 72

1.

BRD4 jump-starts transcription after mitotic silencing.

Voigt P, Reinberg D.

Genome Biol. 2011 Nov 29;12(11):133. doi: 10.1186/gb-2011-12-11-133.

2.

Brd4 marks select genes on mitotic chromatin and directs postmitotic transcription.

Dey A, Nishiyama A, Karpova T, McNally J, Ozato K.

Mol Biol Cell. 2009 Dec;20(23):4899-909. doi: 10.1091/mbc.E09-05-0380. Epub 2009 Oct 7.

3.

Histone acetylation and subcellular localization of chromosomal protein BRD4 during mouse oocyte meiosis and mitosis.

Nagashima T, Maruyama T, Furuya M, Kajitani T, Uchida H, Masuda H, Ono M, Arase T, Ozato K, Yoshimura Y.

Mol Hum Reprod. 2007 Mar;13(3):141-8. Epub 2007 Jan 31.

PMID:
17267518
4.

Gene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation.

Zhao R, Nakamura T, Fu Y, Lazar Z, Spector DL.

Nat Cell Biol. 2011 Oct 9;13(11):1295-304. doi: 10.1038/ncb2341.

5.

The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation.

Wu SY, Chiang CM.

J Biol Chem. 2007 May 4;282(18):13141-5. Epub 2007 Feb 28. Review.

6.

Signal-induced Brd4 release from chromatin is essential for its role transition from chromatin targeting to transcriptional regulation.

Ai N, Hu X, Ding F, Yu B, Wang H, Lu X, Zhang K, Li Y, Han A, Lin W, Liu R, Chen R.

Nucleic Acids Res. 2011 Dec;39(22):9592-604. doi: 10.1093/nar/gkr698. Epub 2011 Sep 2.

7.
8.

Human histone chaperone nucleophosmin enhances acetylation-dependent chromatin transcription.

Swaminathan V, Kishore AH, Febitha KK, Kundu TK.

Mol Cell Biol. 2005 Sep;25(17):7534-45.

9.

Structural basis and binding properties of the second bromodomain of Brd4 with acetylated histone tails.

Liu Y, Wang X, Zhang J, Huang H, Ding B, Wu J, Shi Y.

Biochemistry. 2008 Jun 17;47(24):6403-17. doi: 10.1021/bi8001659. Epub 2008 May 24.

PMID:
18500820
10.

Intracellular delivery of acetyl-histone peptides inhibits native bromodomain-chromatin interactions and impairs mitotic progression.

Nishiyama A, Mochizuki K, Mueller F, Karpova T, McNally JG, Ozato K.

FEBS Lett. 2008 Apr 30;582(10):1501-7. doi: 10.1016/j.febslet.2008.03.044. Epub 2008 Apr 7.

11.

Functional interdependence of BRD4 and DOT1L in MLL leukemia.

Gilan O, Lam EY, Becher I, Lugo D, Cannizzaro E, Joberty G, Ward A, Wiese M, Fong CY, Ftouni S, Tyler D, Stanley K, MacPherson L, Weng CF, Chan YC, Ghisi M, Smil D, Carpenter C, Brown P, Garton N, Blewitt ME, Bannister AJ, Kouzarides T, Huntly BJ, Johnstone RW, Drewes G, Dawson SJ, Arrowsmith CH, Grandi P, Prinjha RK, Dawson MA.

Nat Struct Mol Biol. 2016 Jul;23(7):673-81. doi: 10.1038/nsmb.3249. Epub 2016 Jun 13.

PMID:
27294782
12.

Brd4 links chromatin targeting to HPV transcriptional silencing.

Wu SY, Lee AY, Hou SY, Kemper JK, Erdjument-Bromage H, Tempst P, Chiang CM.

Genes Dev. 2006 Sep 1;20(17):2383-96. Epub 2006 Aug 18.

13.

The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis.

Dey A, Chitsaz F, Abbasi A, Misteli T, Ozato K.

Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8758-63. Epub 2003 Jul 2.

14.

Bromodomain protein Brd4 associated with acetylated chromatin is important for maintenance of higher-order chromatin structure.

Wang R, Li Q, Helfer CM, Jiao J, You J.

J Biol Chem. 2012 Mar 30;287(14):10738-52. doi: 10.1074/jbc.M111.323493. Epub 2012 Feb 10.

15.

Phospho switch triggers Brd4 chromatin binding and activator recruitment for gene-specific targeting.

Wu SY, Lee AY, Lai HT, Zhang H, Chiang CM.

Mol Cell. 2013 Mar 7;49(5):843-57. doi: 10.1016/j.molcel.2012.12.006. Epub 2013 Jan 11.

16.

Aberrant epigenetic regulation of bromodomain BRD4 in human colon cancer.

Rodriguez RM, Huidobro C, Urdinguio RG, Mangas C, Soldevilla B, Domínguez G, Bonilla F, Fernandez AF, Fraga MF.

J Mol Med (Berl). 2012 May;90(5):587-95. doi: 10.1007/s00109-011-0837-0. Epub 2011 Nov 27.

PMID:
22120039
17.

Centromeric histone variant CENP-A represses acetylation-dependent chromatin transcription that is relieved by histone chaperone NPM1.

Shandilya J, Senapati P, Hans F, Menoni H, Bouvet P, Dimitrov S, Angelov D, Kundu TK.

J Biochem. 2014 Oct;156(4):221-7. doi: 10.1093/jb/mvu034. Epub 2014 May 16.

PMID:
24839294
18.

Circadian and light-induced transcription of clock gene Per1 depends on histone acetylation and deacetylation.

Naruse Y, Oh-hashi K, Iijima N, Naruse M, Yoshioka H, Tanaka M.

Mol Cell Biol. 2004 Jul;24(14):6278-87.

19.

A Genetically Encoded FRET Probe to Detect Intranucleosomal Histone H3K9 or H3K14 Acetylation Using BRD4, a BET Family Member.

Nakaoka S, Sasaki K, Ito A, Nakao Y, Yoshida M.

ACS Chem Biol. 2016 Mar 18;11(3):729-33. doi: 10.1021/cb501046t. Epub 2015 May 15.

PMID:
25946208
20.

Brd4-independent transcriptional repression function of the papillomavirus e2 proteins.

Schweiger MR, Ottinger M, You J, Howley PM.

J Virol. 2007 Sep;81(18):9612-22. Epub 2007 Jul 11.

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