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Items: 1 to 20 of 232


JAK/STAT/SOCS-signaling pathway and colon and rectal cancer.

Slattery ML, Lundgreen A, Kadlubar SA, Bondurant KL, Wolff RK.

Mol Carcinog. 2013 Feb;52(2):155-66. doi: 10.1002/mc.21841.


Genetic variation in the JAK/STAT/SOCS signaling pathway influences breast cancer-specific mortality through interaction with cigarette smoking and use of aspirin/NSAIDs: the Breast Cancer Health Disparities Study.

Slattery ML, Lundgreen A, Hines LM, Torres-Mejia G, Wolff RK, Stern MC, John EM.

Breast Cancer Res Treat. 2014 Aug;147(1):145-58. doi: 10.1007/s10549-014-3071-y.


Polymorphisms in JAK/STAT signaling pathway genes and risk of non-Hodgkin lymphoma.

Chen Y, Lan Q, Zheng T, Zhao N, Holford TR, Lerro C, Dai M, Huang H, Liang J, Ma S, Leaderer B, Boyle P, Chanock S, Rothman N, Zhang Y.

Leuk Res. 2013 Sep;37(9):1120-4. doi: 10.1016/j.leukres.2013.05.003.


Suppressors of cytokine signaling modulate JAK/STAT-mediated cell responses during atherosclerosis.

Ortiz-Muñoz G, Martin-Ventura JL, Hernandez-Vargas P, Mallavia B, Lopez-Parra V, Lopez-Franco O, Muñoz-Garcia B, Fernandez-Vizarra P, Ortega L, Egido J, Gomez-Guerrero C.

Arterioscler Thromb Vasc Biol. 2009 Apr;29(4):525-31. doi: 10.1161/ATVBAHA.108.173781.


JAK kinases overexpression promotes in vitro cell transformation.

Knoops L, Hornakova T, Royer Y, Constantinescu SN, Renauld JC.

Oncogene. 2008 Mar 6;27(11):1511-9.


Interleukin genes and associations with colon and rectal cancer risk and overall survival.

Bondurant KL, Lundgreen A, Herrick JS, Kadlubar S, Wolff RK, Slattery ML.

Int J Cancer. 2013 Feb 15;132(4):905-15. doi: 10.1002/ijc.27660.


Acute alcohol intake induces SOCS1 and SOCS3 and inhibits cytokine-induced STAT1 and STAT3 signaling in human monocytes.

Norkina O, Dolganiuc A, Catalano D, Kodys K, Mandrekar P, Syed A, Efros M, Szabo G.

Alcohol Clin Exp Res. 2008 Sep;32(9):1565-73. doi: 10.1111/j.1530-0277.2008.00726.x.


Genetic variation in selenoprotein genes, lifestyle, and risk of colon and rectal cancer.

Slattery ML, Lundgreen A, Welbourn B, Corcoran C, Wolff RK.

PLoS One. 2012;7(5):e37312. doi: 10.1371/journal.pone.0037312.


"Activated" STAT proteins: a paradoxical consequence of inhibited JAK-STAT signaling in cytomegalovirus-infected cells.

Trilling M, Le VT, Rashidi-Alavijeh J, Katschinski B, Scheller J, Rose-John S, Androsiac GE, Jonjic S, Poli V, Pfeffer K, Hengel H.

J Immunol. 2014 Jan 1;192(1):447-58. doi: 10.4049/jimmunol.1203516.


A novel requirement for Janus kinases as mediators of drug resistance induced by fibroblast growth factor-2 in human cancer cells.

Carmo CR, Lyons-Lewis J, Seckl MJ, Costa-Pereira AP.

PLoS One. 2011;6(5):e19861. doi: 10.1371/journal.pone.0019861.


IL28B inhibits hepatitis C virus replication through the JAK-STAT pathway.

Zhang L, Jilg N, Shao RX, Lin W, Fusco DN, Zhao H, Goto K, Peng LF, Chen WC, Chung RT.

J Hepatol. 2011 Aug;55(2):289-98. doi: 10.1016/j.jhep.2010.11.019.


JAK and STAT proteins are expressed and activated by IFN-gamma in rat pancreatic acinar cells.

Gallmeier E, Schäfer C, Moubarak P, Tietz A, Plössl I, Huss R, Göke B, Wagner AC.

J Cell Physiol. 2005 Apr;203(1):209-16.


Functional conservation of suppressors of cytokine signaling proteins between teleosts and mammals: Atlantic salmon SOCS1 binds to JAK/STAT family members and suppresses type I and II IFN signaling.

Skjesol A, Liebe T, Iliev DB, Thomassen EI, Tollersrud LG, Sobhkhez M, Lindenskov Joensen L, Secombes CJ, Jørgensen JB.

Dev Comp Immunol. 2014 Jul;45(1):177-89. doi: 10.1016/j.dci.2014.02.009.


Histone deacetylases inhibitor sodium butyrate inhibits JAK2/STAT signaling through upregulation of SOCS1 and SOCS3 mediated by HDAC8 inhibition in myeloproliferative neoplasms.

Gao SM, Chen CQ, Wang LY, Hong LL, Wu JB, Dong PH, Yu FJ.

Exp Hematol. 2013 Mar;41(3):261-70.e4. doi: 10.1016/j.exphem.2012.10.012.


The JAK-inhibitor, JAB/SOCS-1 selectively inhibits cytokine-induced, but not v-Src induced JAK-STAT activation.

Iwamoto T, Senga T, Naito Y, Matsuda S, Miyake Y, Yoshimura A, Hamaguchi M.

Oncogene. 2000 Sep 28;19(41):4795-801.


Association of JAK-STAT pathway related genes with lymphoma risk: results of a European case-control study (EpiLymph).

Butterbach K, Beckmann L, de Sanjosé S, Benavente Y, Becker N, Foretova L, Maynadie M, Cocco P, Staines A, Boffetta P, Brennan P, Nieters A.

Br J Haematol. 2011 May;153(3):318-33. doi: 10.1111/j.1365-2141.2011.08632.x.


A pathway approach to evaluating the association between the CHIEF pathway and risk of colorectal cancer.

Slattery ML, Wolff RK, Lundgreen A.

Carcinogenesis. 2015 Jan;36(1):49-59. doi: 10.1093/carcin/bgu213.

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