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Items: 1 to 20 of 187

1.

The NLRP3 inflammasome is active but not essential in endotoxin-induced uveitis.

Rosenzweig HL, Woods A, Clowers JS, Planck SR, Rosenbaum JT.

Inflamm Res. 2012 Mar;61(3):225-31. doi: 10.1007/s00011-011-0404-8.

2.

Caspase-1 autoproteolysis is differentially required for NLRP1b and NLRP3 inflammasome function.

Guey B, Bodnar M, Manié SN, Tardivel A, Petrilli V.

Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17254-9. doi: 10.1073/pnas.1415756111.

3.

Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux.

Karmakar M, Katsnelson M, Malak HA, Greene NG, Howell SJ, Hise AG, Camilli A, Kadioglu A, Dubyak GR, Pearlman E.

J Immunol. 2015 Feb 15;194(4):1763-75. doi: 10.4049/jimmunol.1401624.

4.

The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response.

Baroja-Mazo A, Martín-Sánchez F, Gomez AI, Martínez CM, Amores-Iniesta J, Compan V, Barberà-Cremades M, Yagüe J, Ruiz-Ortiz E, Antón J, Buján S, Couillin I, Brough D, Arostegui JI, Pelegrín P.

Nat Immunol. 2014 Aug;15(8):738-48. doi: 10.1038/ni.2919.

PMID:
24952504
5.

Mechanisms that lead to the regulation of NLRP3 inflammasome expression and activation in human dental pulp fibroblasts.

Zhang A, Wang P, Ma X, Yin X, Li J, Wang H, Jiang W, Jia Q, Ni L.

Mol Immunol. 2015 Aug;66(2):253-62. doi: 10.1016/j.molimm.2015.03.009.

6.

The NLRP3/ASC/Caspase-1 axis regulates IL-1β processing in neutrophils.

Mankan AK, Dau T, Jenne D, Hornung V.

Eur J Immunol. 2012 Mar;42(3):710-5. doi: 10.1002/eji.201141921.

7.

Apoptosis-associated speck-like protein containing a caspase recruitment domain inflammasomes mediate IL-1β response and host resistance to Trypanosoma cruzi infection.

Silva GK, Costa RS, Silveira TN, Caetano BC, Horta CV, Gutierrez FR, Guedes PM, Andrade WA, De Niz M, Gazzinelli RT, Zamboni DS, Silva JS.

J Immunol. 2013 Sep 15;191(6):3373-83. doi: 10.4049/jimmunol.1203293.

8.

Shiga Toxins Activate the NLRP3 Inflammasome Pathway To Promote Both Production of the Proinflammatory Cytokine Interleukin-1β and Apoptotic Cell Death.

Lee MS, Kwon H, Lee EY, Kim DJ, Park JH, Tesh VL, Oh TK, Kim MH.

Infect Immun. 2015 Oct 26;84(1):172-86. doi: 10.1128/IAI.01095-15.

9.

An inflammasome-independent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury.

Shigeoka AA, Mueller JL, Kambo A, Mathison JC, King AJ, Hall WF, Correia Jda S, Ulevitch RJ, Hoffman HM, McKay DB.

J Immunol. 2010 Nov 15;185(10):6277-85. doi: 10.4049/jimmunol.1002330. Erratum in: J Immunol. 2011 Feb 1;186(3):1880.

10.

A Yersinia effector with enhanced inhibitory activity on the NF-κB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages.

Zheng Y, Lilo S, Brodsky IE, Zhang Y, Medzhitov R, Marcu KB, Bliska JB.

PLoS Pathog. 2011 Apr;7(4):e1002026. doi: 10.1371/journal.ppat.1002026.

11.

Alcohol-induced IL-1β in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation.

Lippai D, Bala S, Petrasek J, Csak T, Levin I, Kurt-Jones EA, Szabo G.

J Leukoc Biol. 2013 Jul;94(1):171-82. doi: 10.1189/jlb.1212659.

12.

Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome.

Duncan JA, Gao X, Huang MT, O'Connor BP, Thomas CE, Willingham SB, Bergstralh DT, Jarvis GA, Sparling PF, Ting JP.

J Immunol. 2009 May 15;182(10):6460-9. doi: 10.4049/jimmunol.0802696.

13.

Histones trigger sterile inflammation by activating the NLRP3 inflammasome.

Allam R, Darisipudi MN, Tschopp J, Anders HJ.

Eur J Immunol. 2013 Dec;43(12):3336-42. doi: 10.1002/eji.201243224.

14.

Critical role for the NLRP3 inflammasome during acute lung injury.

Grailer JJ, Canning BA, Kalbitz M, Haggadone MD, Dhond RM, Andjelkovic AV, Zetoune FS, Ward PA.

J Immunol. 2014 Jun 15;192(12):5974-83. doi: 10.4049/jimmunol.1400368.

15.

MicroRNA-133a-1 regulates inflammasome activation through uncoupling protein-2.

Bandyopadhyay S, Lane T, Venugopal R, Parthasarathy PT, Cho Y, Galam L, Lockey R, Kolliputi N.

Biochem Biophys Res Commun. 2013 Sep 27;439(3):407-12. doi: 10.1016/j.bbrc.2013.08.056.

16.

Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production.

Hu Y, Mao K, Zeng Y, Chen S, Tao Z, Yang C, Sun S, Wu X, Meng G, Sun B.

J Immunol. 2010 Dec 15;185(12):7699-705. doi: 10.4049/jimmunol.1001099.

17.

Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasome.

Kailasan Vanaja S, Rathinam VA, Atianand MK, Kalantari P, Skehan B, Fitzgerald KA, Leong JM.

Proc Natl Acad Sci U S A. 2014 May 27;111(21):7765-70. doi: 10.1073/pnas.1400075111.

18.

Internalized Cryptococcus neoformans Activates the Canonical Caspase-1 and the Noncanonical Caspase-8 Inflammasomes.

Chen M, Xing Y, Lu A, Fang W, Sun B, Chen C, Liao W, Meng G.

J Immunol. 2015 Nov 15;195(10):4962-72. doi: 10.4049/jimmunol.1500865.

19.

Caspase-11 activates a canonical NLRP3 inflammasome by promoting K(+) efflux.

Rühl S, Broz P.

Eur J Immunol. 2015 Oct;45(10):2927-36. doi: 10.1002/eji.201545772.

20.

The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury.

Sandanger Ø, Ranheim T, Vinge LE, Bliksøen M, Alfsnes K, Finsen AV, Dahl CP, Askevold ET, Florholmen G, Christensen G, Fitzgerald KA, Lien E, Valen G, Espevik T, Aukrust P, Yndestad A.

Cardiovasc Res. 2013 Jul 1;99(1):164-74. doi: 10.1093/cvr/cvt091.

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